Zinc and the Developing Nervous System: Toxic Effects of Zinc on the Central Nervous System of the Preweanling Rabbit

Brain ◽  
1977 ◽  
pp. 124-136
Author(s):  
Arthur L. Prensky ◽  
Laura Hillman
Development ◽  
1959 ◽  
Vol 7 (2) ◽  
pp. 128-145
Author(s):  
Arthur Hughes

In 1913 G. E. Coghill initiated a series of papers on the neuro-embryology of the Urodele Ambystoma with a description of the earliest stages of the motor system of the trunk (Coghill, 1913). His main conclusion is stated early in the paper in these words: The neurones … which establish the earliest contact with the cells of the myotome are found in Amblystoma to be at the same time the neurones of the motor tract in the central nervous system. The primary ventral root fibre is a collateral of the tract cell. (Coghill, 1913, p. 121.) Thirteen years later, among a group of other papers on the developing nervous system of Ambystoma, he returned to this theme, and in a series of examples described the form of the first nerve process within the basal plate of the cord.


Oncoreview ◽  
2016 ◽  
Vol 6 (4) ◽  
pp. 0-0 ◽  
Author(s):  
Łukasz Galus

Ifosfamide is a cytostatic drug commonly used in chemotherapy. One of the common adverse effects resulting from the treatment with ifosfamide is encephalopathy. This paper describes a case study of a 64-year-old patient who suffered from a full-blown encephalopathy as a result of chemotherapy administered during the treatment of fibrosarcoma of the femur. It provides a hypothesis of the mechanism behind toxic effects of ifosfamide on the central nervous system and elaborates on a number of documented ways of preventing aforementioned complications.


Author(s):  
Kohei Shiota

ABSTRACT The organogenesis of the central nervous system (CNS) begins during the third week of development, but its maturation requires a considerably long period of time until after birth. Therefore the developing nervous system is vulnerable to the deleterious effects of environmental factors during the pre- and perinatal periods. In addition, molecular studies have revealed various gene mutations that are responsible for congenital CNS disorders. This chapter provides an overview of the prenatal development of the human brain and spinal cord. How to cite this article Shiota K. Prenatal Development of the Human Central Nervous System, Normal and Abnormal. Donald School J Ultrasound Obstet Gynecol 2015;9(1):61-66.


1954 ◽  
Vol 100 (420) ◽  
pp. 670-677 ◽  
Author(s):  
M. C. H. Dodgson

In view of the importance of prenatal pathology at the present time, a useful purpose may be served by attempting to review the peculiar weaknesses and strengths of the developing nervous system. As a result of personal inclinations, this presentation of the various problems involved will have a structural bias; the subject would, no doubt, be approached very differently by a physiologist, for instance, or by a biochemist. Nevertheless we should all be describing different aspects of the same series of phenomena, aiming at an understanding of the events which must occur before the central nervous system can function.


1983 ◽  
Vol 61 (3-4) ◽  
pp. 291-299 ◽  
Author(s):  
L. Bigotte ◽  
Y. Olsson

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