Structural and Functional Analysis of the FAS1 Gene Encoding Fatty Acid Synthase β-Subunit in Methylotrophic Yeast Hansenula Polymorpha

2003 ◽  
pp. 61-64 ◽  
Author(s):  
Y. Kaneko ◽  
K. Rueksomtawin ◽  
T. Maekawa ◽  
S. Harashima
Keyword(s):  
Functional Analysis ◽  
Fatty Acid ◽  
Fatty Acid Synthase ◽  
Hansenula Polymorpha ◽  
Methylotrophic Yeast ◽  
Β Subunit ◽  
Gene Encoding

Cloning, sequencing, and functional analysis of H-OLE1 gene encoding Δ9-fatty acid desaturase in Hansenula polymorpha

2000 ◽  
Vol 54 (4) ◽  
pp. 499-509 ◽  
Author(s):  
S.-F. Lu ◽  
I. I. Tolstorukov ◽  
S. Anamnart ◽  
Y. Kaneko ◽  
S. Harashima
Keyword(s):  
Functional Analysis ◽  
Fatty Acid ◽  
Hansenula Polymorpha ◽  
Fatty Acid Desaturase ◽  
Gene Encoding ◽  
Ole1 Gene

Functional analysis of very long-chain fatty acid elongase gene, HpELO2, in the methylotrophic yeast Hansenula polymorpha

2007 ◽  
Vol 76 (2) ◽  
pp. 417-427 ◽  
Author(s):  
Phatthanon Prasitchoke ◽  
Yoshinobu Kaneko ◽  
Minetaka Sugiyama ◽  
Takeshi Bamba ◽  
Eiichiro Fukusaki ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Fatty Acid ◽  
Hansenula Polymorpha ◽  
Methylotrophic Yeast ◽  
Chain Fatty Acid ◽  
Long Chain Fatty Acid ◽  
Fatty Acid Elongase ◽  
Long Chain

scholarly journals A Fatty Acid Synthase Gene in Cochliobolus carbonum Required for Production of HC-Toxin, Cyclo(d-Prolyl-l-Alanyl- d-Alanyl- l-2-Amino-9,10-Epoxi-8-Oxodecanoyl)

1997 ◽  
Vol 10 (2) ◽  
pp. 207-214 ◽  
Author(s):  
Joong-Hoon Ahn ◽  
Jonathan D. Walton
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Synthase ◽  
Cyclic Peptide ◽  
Decanoic Acid ◽  
Toxin Production ◽  
Gene Encoding ◽  
Cochliobolus Carbonum ◽  
Primary Amino ◽  
Hc Toxin

The fungal maize pathogen Cochliobolus carbonum produces a phytotoxic and cytostatic cyclic peptide, HC-toxin, of structure cyclo(D-prolyl-L-alanyl-D-alanyl-L-Aeo), in which Aeo stands for 2-amino-9,10-epoxi-8-oxodecanoic acid. Here we report the isolation of a gene, TOXC, that is present only in HC-toxin-producing (Tox2+) fungal strains. TOXC is present in most Tox2+ strains in three functional copies, all of which are on the same chromosome as the gene encoding HC-toxin synthetase. When all copies of TOXC are mutated by targeted gene disruption, the fungus grows and sporulates normally in vitro but no longer makes HC-toxin and is not pathogenic, indicating that TOXC has a specific role in HC-toxin production and hence virulence. The TOXC mRNA is 6.5 kb and the predicted product has 2,080 amino acids and a molecular weight of 233,000. The primary amino acid sequence is highly similar (45 to 47% identity) to the β subunit of fatty acid synthase from several lower eukaryotes, and contains, in the same order as in other β subunits, domains predicted to encode acetyl transferase, enoyl reductase, dehydratase, and malonyl-palmityl transferase. The most plausible function of TOXC is to contribute to the synthesis of the decanoic acid backbone of Aeo.

scholarly journals Campylobacter jejuni fatty acid synthase II: Structural and functional analysis of β-hydroxyacyl-ACP dehydratase (FabZ)

2009 ◽  
Vol 380 (2) ◽  
pp. 407-412 ◽  
Author(s):  
Andrew S. Kirkpatrick ◽  
Takeshi Yokoyama ◽  
Kyoung-Jae Choi ◽  
Hye-Jeong Yeo
Keyword(s):  
Functional Analysis ◽  
Fatty Acid ◽  
Campylobacter Jejuni ◽  
Fatty Acid Synthase

scholarly journals Elongation of C16:0 to C18:0 fatty acids in methylotrophic yeast Hansenula polymorpha CBS 1976 and fatty acid auxotrophic mutants

2004 ◽  
Vol 237 (2) ◽  
pp. 213-218
Author(s):  
Wanida Wongsumpanchai ◽  
Sarintip Anamnart ◽  
Kobkul Laoteng ◽  
Amorn Petsom
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Hansenula Polymorpha ◽  
Methylotrophic Yeast ◽  
Auxotrophic Mutants

scholarly journals Identification and functional analysis of the cyclopropane fatty acid synthase of Brucella abortus

Microbiology ◽  
2012 ◽  
Vol 158 (4) ◽  
pp. 1037-1044 ◽  
Author(s):  
Leyre Palacios-Chaves ◽  
Amaia Zúñiga-Ripa ◽  
Ana Gutiérrez ◽  
Yolanda Gil-Ramírez ◽  
Raquel Conde-Álvarez ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Fatty Acid ◽  
Brucella Abortus ◽  
Fatty Acid Synthase ◽  
Cyclopropane Fatty Acid

Cloning and characterization of the gene encoding a repressible acid phosphatase ( PHO1 ) from the methylotrophic yeast Hansenula polymorpha

1998 ◽  
Vol 50 (1) ◽  
pp. 77-84 ◽  
Author(s):  
A. Phongdara ◽  
A. Merckelbach ◽  
P. Keup ◽  
G. Gellissen ◽  
C. P. Hollenberg
Keyword(s):  
Acid Phosphatase ◽  
Hansenula Polymorpha ◽  
Methylotrophic Yeast ◽  
Gene Encoding

Functional analysis of Mpk1-mediated cell wall integrity signaling pathway in the thermotolerant methylotrophic yeast Hansenula polymorpha

2018 ◽  
Vol 56 (1) ◽  
pp. 72-82 ◽  
Author(s):  
Hyunah Kim ◽  
Eun Jung Thak ◽  
Ji Yoon Yeon ◽  
Min Jeong Sohn ◽  
Jin Ho Choo ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Cell Wall ◽  
Signaling Pathway ◽  
Hansenula Polymorpha ◽  
Methylotrophic Yeast ◽  
Cell Wall Integrity

Cloning and functional analysis of HpFAD2 and HpFAD3 genes encoding Δ12- and Δ15-fatty acid desaturases in Hansenula polymorpha

Gene ◽  
2014 ◽  
Vol 533 (1) ◽  
pp. 110-118 ◽  
Author(s):  
Juthaporn Sangwallek ◽  
Yoshinobu Kaneko ◽  
Tomoya Tsukamoto ◽  
Makoto Marui ◽  
Minetaka Sugiyama ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Fatty Acid ◽  
Hansenula Polymorpha ◽  
Fatty Acid Desaturases ◽  
Genes Encoding

scholarly journals Structural and functional analysis of methylotrophic yeast Hansenula polymorpha alcohol oxydase gene promoter

1995 ◽  
Vol 11 (2) ◽  
pp. 39-45
Author(s):  
O. P. Vitvitskaya ◽  
M. L. Zlochevskii ◽  
M. Yu. Beburov
Keyword(s):  
Functional Analysis ◽  
Hansenula Polymorpha ◽  
Gene Promoter ◽  
Methylotrophic Yeast
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