This paper proposes new approaches for designing a bipolar DS acquisition system to reduce the harm of external factors on equipment, as well as fulfill system requirements at the veracity and reliability of the equipment to quickly connect. The design method chosen is ACPL-224 for chip of the interface about data acquisition on the FPGA device, including system principle, interface circuit logic, the method of data processing, and so forth. Now that this method has been applied, it has achieved good results, including extending the system’s adaptive range of external signal and enhancing the efficiency of the interface to quickly connect.