A Framework for Examining Teachers’ Practical Knowledge for STEM Teaching

Social remittances (ideas, system practice, and social capital flow from the receiving country to the home country) of Indonesian female migrant workers (BMP) in Hong Kong appeared better and more complete than other BMP in other countries like Malaysia, Saudi Arabia, or Singapore. Based on that research, we are encouraged to do extensive research in order to identify factors that push BMP’s social remittances development in Hong Kong, to identify kinds of social remmitances they receive and to understand on how far their social remittances become a medium to empower them and their society. This study is done in qualitative method that uses an in-depth interview technique and FGD. Subjects of study are BMP, the government (Ministry of Manpower and Transmigration and BNP2TKI), NGOs, migrant workers’ organization and researchers of BMP. The study done in Cianjur (West Java), Wonosobo and Banyumas (Central Java) and Hong Kong indicates that during their migration process, female migrant workers not only have economical remittance that can be used for productive activities, but also social remittances. The social remittances are in the form practical knowledge such as language skill and nursery; knowledge on health, financial management; ethical work; the mindset changing and networking. The study indicate that female migrant workers are extraordinary women more than just an ex-helper. Their migration has put them into a position as an agent of development in society.Key words: Indonesians female migrant workers, social remmitances, empowerment

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A Study on Life History Beliefs of the Special Education Teachers: The relationship between critical thinking disposition and practical knowledge contents

The Korean Journal of Political Science ◽

10.34221/kjps.2018.26.2.5 ◽

2018 ◽

Vol 26 (2) ◽

pp. 93-112

Author(s):

Sung Kyu Choi ◽

Sung Bum Kim

Keyword(s):

Special Education ◽

Life History ◽

Critical Thinking ◽

Special Education Teachers ◽

Practical Knowledge ◽

Critical Thinking Disposition ◽

Thinking Disposition ◽

The Relationship

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Structure-Based Virtual Screening and Biochemical Evaluation for the Identification of Novel Trypanosoma brucei Aldolase Inhibitors

Current Topics in Medicinal Chemistry ◽

10.2174/1568026618666180427150428 ◽

2018 ◽

Vol 18 (5) ◽

pp. 397-405 ◽

Cited By ~ 2

Author(s):

Leonardo L.G. Ferreira ◽

Rafaela S. Ferreira ◽

David L. Palomino ◽

Adriano D. Andricopulo

Keyword(s):

Drug Discovery ◽

Virtual Screening ◽

Trypanosoma Brucei ◽

Enzyme Inhibitor ◽

Practical Knowledge ◽

Glycolytic Enzyme ◽

Structure Based Drug Design ◽

Biochemical Evaluation ◽

Dynamics Simulations ◽

Fructose 1,6 Bisphosphate

Introduction: The glycolytic enzyme fructose-1,6-bisphosphate aldolase is a validated molecular target in human African trypanosomiasis (HAT) drug discovery, a neglected tropical disease (NTD) caused by the protozoan Trypanosoma brucei. Herein, a structure-based virtual screening (SBVS) approach to the identification of novel T. brucei aldolase inhibitors is described. Distinct molecular docking algorithms were used to screen more than 500,000 compounds against the X-ray structure of the enzyme. This SBVS strategy led to the selection of a series of molecules which were evaluated for their activity on recombinant T. brucei aldolase. The effort led to the discovery of structurally new ligands able to inhibit the catalytic activity of the enzyme. Results: The predicted binding conformations were additionally investigated in molecular dynamics simulations, which provided useful insights into the enzyme-inhibitor intermolecular interactions. Conclusion: The molecular modeling results along with the enzyme inhibition data generated practical knowledge to be explored in further structure-based drug design efforts in HAT drug discovery.

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