Biomedical Applications of Biodegradable Polymers in Wound Care

2021 ◽  
pp. 509-597
Author(s):  
Sónia P. Miguel ◽  
Maximiano P. Ribeiro ◽  
Paula Coutinho



Polymers ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 920 ◽  
Author(s):  
Tanja Narancic ◽  
Federico Cerrone ◽  
Niall Beagan ◽  
Kevin E. O’Connor

The success of oil-based plastics and the continued growth of production and utilisation can be attributed to their cost, durability, strength to weight ratio, and eight contributions to the ease of everyday life. However, their mainly single use, durability and recalcitrant nature have led to a substantial increase of plastics as a fraction of municipal solid waste. The need to substitute single use products that are not easy to collect has inspired a lot of research towards finding sustainable replacements for oil-based plastics. In addition, specific physicochemical, biological, and degradation properties of biodegradable polymers have made them attractive materials for biomedical applications. This review summarises the advances in drug delivery systems, specifically design of nanoparticles based on the biodegradable polymers. We also discuss the research performed in the area of biophotonics and challenges and opportunities brought by the design and application of biodegradable polymers in tissue engineering. We then discuss state-of-the-art research in the design and application of biodegradable polymers in packaging and emphasise the advances in smart packaging development. Finally, we provide an overview of the biodegradation of these polymers and composites in managed and unmanaged environments.



2003 ◽  
Vol 65A (1) ◽  
pp. 60-70 ◽  
Author(s):  
C. M. Vaz ◽  
M. Fossen ◽  
R. F. van Tuil ◽  
L. A. de Graaf ◽  
R. L. Reis ◽  
...  


2011 ◽  
Vol 49 (12) ◽  
pp. 832-864 ◽  
Author(s):  
Bret D. Ulery ◽  
Lakshmi S. Nair ◽  
Cato T. Laurencin


2021 ◽  
Vol 9 (5) ◽  
pp. 334-345
Author(s):  
N. Surya ◽  
S. Bhattacharyya

Polymers have become an integral part of novel drug delivery system. One such successful biodegradable polymer is poly lactic-co-glycolic acid (PLGA) which consists of polyesters of lactic acid and glycolic acid. It is one of the FDA-approved biodegradable polymers which is extensively used for therapeutic purposes in recent times.The aim. To illuminate researchers on the chemistry, novel properties and applications of PLGA in pharmaceutical fields.Materials and methods. Various internet sources like Science Direct, Scopus, Web of Science, PubMed and google scholar were used as the data source. The key words search was carried out for the following words and combinations: PLGA, Novel drug delivery, PLGA Nano particles, biomedical applications of PLGA.Results. Pharmaceutical and biomedical industries are flooded with the use of synthetic and natural polymers. The mechanical and viscoelastic properties of the polymers make them suitable for the temporal and spatial delivery of therapeutic agents for an extended period. Employment of copolymerization techniques lead to the modification of water solubility of the polymers and make them suitable for various applications of drug delivery systems. Biodegradable polymers due to their biocompatibility and biodegradable property have attracted their use in novel drug delivery systems. PLGA is one of them. PLGA is versatile as it can be fabricated into any size, shape, and can be used to encapsulate small molecules, tissue engineering, and bone repair, etc.Conclusion. The sensitivity and biodegradability of PLGA makes it a smart polymer for targeted and sustained delivery of drugs and in various biomedical applications.



2014 ◽  
pp. 295-357 ◽  
Author(s):  
Mohammad Sirousazar ◽  
Mehrdad Forough ◽  
Khalil Farhadi ◽  
Yasaman Shaabani ◽  
Rahim Molaei






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