scholarly journals Recent Advances in Bioplastics: Application and Biodegradation

Polymers ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 920 ◽  
Author(s):  
Tanja Narancic ◽  
Federico Cerrone ◽  
Niall Beagan ◽  
Kevin E. O’Connor
Keyword(s):  
Biodegradable Polymers ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
State Of The Art ◽  
Weight Ratio ◽  
Challenges And Opportunities ◽  
Single Use ◽  
Art Research ◽  
Degradation Properties ◽  
Design And Application

The success of oil-based plastics and the continued growth of production and utilisation can be attributed to their cost, durability, strength to weight ratio, and eight contributions to the ease of everyday life. However, their mainly single use, durability and recalcitrant nature have led to a substantial increase of plastics as a fraction of municipal solid waste. The need to substitute single use products that are not easy to collect has inspired a lot of research towards finding sustainable replacements for oil-based plastics. In addition, specific physicochemical, biological, and degradation properties of biodegradable polymers have made them attractive materials for biomedical applications. This review summarises the advances in drug delivery systems, specifically design of nanoparticles based on the biodegradable polymers. We also discuss the research performed in the area of biophotonics and challenges and opportunities brought by the design and application of biodegradable polymers in tissue engineering. We then discuss state-of-the-art research in the design and application of biodegradable polymers in packaging and emphasise the advances in smart packaging development. Finally, we provide an overview of the biodegradation of these polymers and composites in managed and unmanaged environments.

scholarly journals PLGA – THE SMART POLYMER FOR DRUG DELIVERY

2021 ◽  
Vol 9 (5) ◽  
pp. 334-345
Author(s):  
N. Surya ◽  
S. Bhattacharyya
Keyword(s):  
Drug Delivery ◽  
Biodegradable Polymers ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
Glycolic Acid ◽  
Delivery Systems ◽  
Nano Particles ◽  
Natural Polymers ◽  
Smart Polymer ◽  
Novel Drug

Polymers have become an integral part of novel drug delivery system. One such successful biodegradable polymer is poly lactic-co-glycolic acid (PLGA) which consists of polyesters of lactic acid and glycolic acid. It is one of the FDA-approved biodegradable polymers which is extensively used for therapeutic purposes in recent times.The aim. To illuminate researchers on the chemistry, novel properties and applications of PLGA in pharmaceutical fields.Materials and methods. Various internet sources like Science Direct, Scopus, Web of Science, PubMed and google scholar were used as the data source. The key words search was carried out for the following words and combinations: PLGA, Novel drug delivery, PLGA Nano particles, biomedical applications of PLGA.Results. Pharmaceutical and biomedical industries are flooded with the use of synthetic and natural polymers. The mechanical and viscoelastic properties of the polymers make them suitable for the temporal and spatial delivery of therapeutic agents for an extended period. Employment of copolymerization techniques lead to the modification of water solubility of the polymers and make them suitable for various applications of drug delivery systems. Biodegradable polymers due to their biocompatibility and biodegradable property have attracted their use in novel drug delivery systems. PLGA is one of them. PLGA is versatile as it can be fabricated into any size, shape, and can be used to encapsulate small molecules, tissue engineering, and bone repair, etc.Conclusion. The sensitivity and biodegradability of PLGA makes it a smart polymer for targeted and sustained delivery of drugs and in various biomedical applications.

scholarly journals Research Challenges and Opportunities in Drone Forensics Models

Electronics ◽  
2021 ◽  
Vol 10 (13) ◽  
pp. 1519
Author(s):  
Arafat Al-Dhaqm ◽  
Richard A. Ikuesan ◽  
Victor R. Kebande ◽  
Shukor Razak ◽  
Fahad M. Ghabban
Keyword(s):  
State Of The Art ◽  
Design Science ◽  
Science Research ◽  
Related Event ◽  
Digital Forensic ◽  
Supply Chain Logistics ◽  
Research Challenges ◽  
Challenges And Opportunities ◽  
Art Research ◽  
Digital Landscape

The emergence of unmanned aerial vehicles (also referred to as drones) has transformed the digital landscape of surveillance and supply chain logistics, especially in terrains where such was previously deemed unattainable. Moreover, the adoption of drones has further led to the proliferation of diverse drone types and drone-related criminality, which has introduced a myriad of security and forensics-related concerns. As a step towards understanding the state-of-the-art research into these challenges and potential approaches to mitigation, this study provides a detailed review of existing digital forensic models using the Design Science Research method. The outcome of this study generated in-depth knowledge of the research challenges and opportunities through which an effective investigation can be carried out on drone-related incidents. Furthermore, a potential generic investigation model has been proposed. The findings presented in this study are essentially relevant to forensic researchers and practitioners towards a guided methodology for drone-related event investigation. Ultimately, it is important to mention that this study presents a background for the development of international standardization for drone forensics.

scholarly journals ELECTROSPUN BIOMATERIALS AND RELATED TECHNOLOGIES

2019 ◽  
Vol 8 (2) ◽  
pp. 168 ◽  
Author(s):  
Adhi Anindyajati
Keyword(s):  
Biomedical Applications ◽  
Chemical Engineering ◽  
State Of The Art ◽  
Collagen Scaffold ◽  
Research Experiences ◽  
Retinal Tissue ◽  
Nerve Conduits ◽  
Reading Text ◽  
Process Reproducibility ◽  
Art Research

Electrospun Biomaterials and Related Technologies is a multi-contributed book containing review articles from worldwide authors with industry and academic background. This book is aimed to deliver a compiled overview in biomaterials electrospinning, including strategies, relevant technologies, and state-of-the-art research. The editor, Jorge Almodovar, has chemical engineering background with extensive research experiences and focus on engineering of biomimetic materials. The book consists of nine chapters in 282 content pages. Arranged in a concise format, it delivers a comprehensive but not exhaustive reading text. The chapters cover broad range of topics in electrospinning field, including process reproducibility and robustness, fibrous collagen scaffold, cellulose-based biomaterials, biopolymer nanofibres, green electrospinning, electrospun materials for cancer research, nanofibrous nerve conduits, scaffold for retinal tissue engineering, and smart material. These topics are mainly related to biomedical applications, but studies on environmental engineering are also conferred.

Rediscovering Tocophersolan: a renaissance for nano-based drug delivery and nanotheranostic applications

2020 ◽  
Vol 21 ◽  
Author(s):  
Dickson Pius Wande ◽  
Qin Cui ◽  
Shijie Chen ◽  
Cheng Xu ◽  
Hui Xiong ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Drug Dissolution ◽  
Glycol Succinate ◽  
Permeation Enhancer ◽  
P Glycoprotein ◽  
Us Fda ◽  
Anticancer Compound

: As a unique and pleiotropic polymer, d-alpha-tocopheryl polyethylene glycol succinate (Tocophersolan) is a polymeric synthetic version of vitamin E. Tocophersolan has attracted enormous attention as a versatile excipient in different biomedical applications including drug delivery systems and nutraceuticals. The multiple inherent properties of Tocophersolan make it play flexible roles in drug delivery system design, including excipients with outstanding biocompatibility, solubilizer with the ability of promoting drug dissolution, drug permeation enhancer, P-glycoprotein inhibitor and anticancer compound. For these reasons, Tocophersolan has been widely used for improving the bioavailability of numerous pharmaceutical active ingredients. Tocophersolan has been approved by stringent regulatory authorities (such as US FDA, EMA, and PMDA) as a safe pharmaceutical excipient. In this review, we systematically curated current advances in nano-based delivery systems consisting of Tocophersolan with possibilities for futuristic applications in drug delivery, gene therapy, and nanotheranostic.

Chitosan Nanoparticles: An Approbative System for the Delivery of Herbal Bioactives

2020 ◽  
Vol 10 ◽  
Author(s):  
Sapna Saini ◽  
Sanju Nanda ◽  
Anju Dhiman
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
State Of The Art ◽  
Chitosan Nanoparticles ◽  
Delivery Systems ◽  
Intrinsic Properties ◽  
Amino Groups ◽  
Suitable Candidate ◽  
Film Forming ◽  
Novel Drug

: Chitosan, a natural biodegradable polymer obtained from deacetylation of chitin, has been used as an approbative macromolecule for the development of various novel drug delivery systems. It is one of the most favorable biodegradable carriers for nanoparticulate drug delivery due to its intrinsic properties, such as biocompatibility, biodegradability, non-toxicity, availability of free reactive amino groups, and ease of chemical modification into different active derivatives. Furthermore, interesting physical properties (film-forming, gelling and thickening) make it a suitable candidate for formulations, such as films, microcapsules, beads, nanoparticles, nanofibres, nanogel and so on. Researchers have reported that chitosan nanoparticles act as a promising vehicle for herbal actives as they provide a superior alternative to traditional carriers and improve pharmaceutical efficiency. As no review of chitosan nanoparticles encapsulating herbal extracts and bioactives has been published till date, a maiden effort has been made to collate and review the use of chitosan nanoparticles for the entrapment of phytoconstituents to yield stable, efficient and safe drug delivery systems. Additionally, the paper presents a comprehensive account of the state-of the-art in fabricating herbal chitosan nanoparticles and their current pharmacological status. A list of patents on chitosan nanoparticles of herbal actives has also been included. This review is intended to serve as a didactic discourse for the formulation scientists endeavoring to develop advanced delivery systems for herbal actives.

scholarly journals Water-Worked Gravel Bed: State-of-the-Art Review

Water ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 694 ◽  
Author(s):  
Ellora Padhi ◽  
Subhasish Dey ◽  
Venkappayya R. Desai ◽  
Nadia Penna ◽  
Roberto Gaudio
Keyword(s):  
State Of The Art ◽  
Flow Characteristics ◽  
Streamwise Velocity ◽  
Secondary Currents ◽  
Gravel Bed ◽  
Natural Stream ◽  
Art Research ◽  
The Comparative Study ◽  
Water Work

In a natural gravel-bed stream, the bed that has an organized roughness structure created by the streamflow is called the water-worked gravel bed (WGB). Such a bed is entirely different from that created in a laboratory by depositing and spreading gravels in the experimental flume, called the screeded gravel bed (SGB). In this paper, a review on the state-of-the-art research on WGBs is presented, highlighting the role of water-work in determining the bed topographical structures and the turbulence characteristics in the flow. In doing so, various methods used to analyze the bed topographical structures are described. Besides, the effects of the water-work on the turbulent flow characteristics, such as streamwise velocity, Reynolds and form-induced stresses, conditional turbulent events and secondary currents in WGBs are discussed. Further, the results form WGBs and SGBs are compared critically. The comparative study infers that a WGB exhibits a higher roughness than an SGB. Consequently, the former has a higher magnitude of turbulence parameters than the latter. Finally, as a future scope of research, laboratory experiments should be conducted in WGBs rather than in SGBs to have an appropriate representation of the flow field close to a natural stream.

Sign in / Sign up

Export Citation Format

Share Document