In Medicine Deep Learning has become an essential tool to achieve outstanding diagnosis on image data. However, one critical problem is that Deep Learning comes with complicated, black-box models so it is not possible to analyze their trust level directly. So, Explainable Artificial Intelligence (XAI) methods are used to build additional interfaces for explaining how the model has reached the outputs by moving from the input data. Of course, that's again another competitive problem to analyze if such methods are successful according to the human view. So, this paper comes with two important research efforts: (1) to build an explainable deep learning model targeting medical image analysis, and (2) to evaluate the trust level of this model via several evaluation works including human contribution. The target problem was selected as the brain tumor classification, which is a remarkable, competitive medical image-based problem for Deep Learning. In the study, MR-based pre-processed brain images were received by the Subtractive Spatial Lightweight Convolutional Neural Network (SSLW-CNN) model, which includes additional operators to reduce the complexity of classification. In order to ensure the explainable background, the model also included Class Activation Mapping (CAM). It is important to evaluate the trust level of a successful model. So, numerical success rates of the SSLW-CNN were evaluated based on the peak signal-to-noise ratio (PSNR), computational time, computational overhead, and brain tumor classification accuracy. The objective of the proposed SSLW-CNN model is to obtain faster and good tumor classification with lesser time. The results illustrate that the SSLW-CNN model provides better performance of PSNR which is enhanced by 8%, classification accuracy is improved by 33%, computation time is reduced by 19%, computation overhead is decreased by 23%, and classification time is minimized by 13%, as compared to state-of-the-art works. Because the model provided good numerical results, it was then evaluated in terms of XAI perspective by including doctor-model based evaluations such as feedback CAM visualizations, usability, expert surveys, comparisons of CAM with other XAI methods, and manual diagnosis comparison. The results show that the SSLW-CNN provides good performance on brain tumor diagnosis and ensures a trustworthy solution for the doctors.
Deep Learning for Brain Tumor Segmentation: A Survey of State-of-the-Art
