Evaluation of Automated Measurement of Hair Density Using Deep Neural Networks

Recently, deep learning has been employed in medical image analysis for several clinical imaging methods, such as X-ray, computed tomography, magnetic resonance imaging, and pathological tissue imaging, and excellent performance has been reported. With the development of these methods, deep learning technologies have rapidly evolved in the healthcare industry related to hair loss. Hair density measurement (HDM) is a process used for detecting the severity of hair loss by counting the number of hairs present in the occipital donor region for transplantation. HDM is a typical object detection and classification problem that could benefit from deep learning. This study analyzed the accuracy of HDM by applying deep learning technology for object detection and reports the feasibility of automating HDM. The dataset for training and evaluation comprised 4492 enlarged hair scalp RGB images obtained from male hair-loss patients and the corresponding annotation data that contained the location information of the hair follicles present in the image and follicle-type information according to the number of hairs. EfficientDet, YOLOv4, and DetectoRS were used as object detection algorithms for performance comparison. The experimental results indicated that YOLOv4 had the best performance, with a mean average precision of 58.67.

Artificial Intelligence Applications in the Imaging of Epilepsy and Its Comorbidities: Present and Future

Artificial intelligence (AI) is increasingly used in medical image analysis and has accelerated scientific discoveries across fields of medicine. In this review, we highlight how AI has been applied to neuroimaging in patients with epilepsy to enhance classification of clinical diagnosis, prediction of treatment outcomes, and the understanding of cognitive comorbidities. We outline the strengths and shortcomings of current AI research and the need for future studies using large datasets that test the reproducibility and generalizability of current findings, as well as studies that test the clinical utility of AI approaches.

Application of Artificial Intelligence in Cardiovascular Imaging

During the last two decades, as computer technology has matured and business scenarios have diversified, the scale of application of computer systems in various industries has continued to expand, resulting in a huge increase in industry data. As for the medical industry, huge unstructured data has been accumulated, so exploring how to use medical image data more effectively to efficiently complete diagnosis has an important practical impact. For a long time, China has been striving to promote the process of medical informatization, and the combination of big data and artificial intelligence and other advanced technologies in the medical field has become a hot industry and a new development trend. This paper focuses on cardiovascular diseases and uses relevant deep learning methods to realize automatic analysis and diagnosis of medical images and verify the feasibility of AI-assisted medical treatment. We have tried to achieve a complete diagnosis of cardiovascular medical imaging and localize the vulnerable lesion area. (1) We tested the classical object based on a convolutional neural network and experiment, explored the region segmentation algorithm, and showed its application scenarios in the field of medical imaging. (2) According to the data and task characteristics, we built a network model containing classification nodes and regression nodes. After the multitask joint drill, the effect of diagnosis and detection was also enhanced. In this paper, a weighted loss function mechanism is used to improve the imbalance of data between classes in medical image analysis, and the effect of the model is enhanced. (3) In the actual medical process, many medical images have the label information of high-level categories but lack the label information of low-level lesions. The proposed system exposes the possibility of lesion localization under weakly supervised conditions by taking cardiovascular imaging data to resolve these issues. Experimental results have verified that the proposed deep learning-enabled model has the capacity to resolve the aforementioned issues with minimum possible changes in the underlined infrastructure.

Training calibration-based counterfactual explainers for deep learning models in medical image analysis

The rapid adoption of artificial intelligence methods in healthcare is coupled with the critical need for techniques to rigorously introspect models and thereby ensure that they behave reliably. This has led to the design of explainable AI techniques that uncover the relationships between discernible data signatures and model predictions. In this context, counterfactual explanations that synthesize small, interpretable changes to a given query while producing desired changes in model predictions have become popular. This under-constrained, inverse problem is vulnerable to introducing irrelevant feature manipulations, particularly when the model’s predictions are not well-calibrated. Hence, in this paper, we propose the TraCE (training calibration-based explainers) technique, which utilizes a novel uncertainty-based interval calibration strategy for reliably synthesizing counterfactuals. Given the wide-spread adoption of machine-learned solutions in radiology, our study focuses on deep models used for identifying anomalies in chest X-ray images. Using rigorous empirical studies, we demonstrate the superiority of TraCE explanations over several state-of-the-art baseline approaches, in terms of several widely adopted evaluation metrics. Our findings show that TraCE can be used to obtain a holistic understanding of deep models by enabling progressive exploration of decision boundaries, to detect shortcuts, and to infer relationships between patient attributes and disease severity.

Medical domain knowledge in domain-agnostic generative AI

The text-guided diffusion model GLIDE (Guided Language to Image Diffusion for Generation and Editing) is the state of the art in text-to-image generative artificial intelligence (AI). GLIDE has rich representations, but medical applications of this model have not been systematically explored. If GLIDE had useful medical knowledge, it could be used for medical image analysis tasks, a domain in which AI systems are still highly engineered towards a single use-case. Here we show that the publicly available GLIDE model has reasonably strong representations of key topics in cancer research and oncology, in particular the general style of histopathology images and multiple facets of diseases, pathological processes and laboratory assays. However, GLIDE seems to lack useful representations of the style and content of radiology data. Our findings demonstrate that domain-agnostic generative AI models can learn relevant medical concepts without explicit training. Thus, GLIDE and similar models might be useful for medical image processing tasks in the future - particularly with additional domain-specific fine-tuning.

Deep Learning for Orthopedic Disease Based on Medical Image Analysis: Present and Future

Since its development, deep learning has been quickly incorporated into the field of medicine and has had a profound impact. Since 2017, many studies applying deep learning-based diagnostics in the field of orthopedics have demonstrated outstanding performance. However, most published papers have focused on disease detection or classification, leaving some unsatisfactory reports in areas such as segmentation and prediction. This review introduces research published in the field of orthopedics classified according to disease from the perspective of orthopedic surgeons, and areas of future research are discussed. This paper provides orthopedic surgeons with an overall understanding of artificial intelligence-based image analysis and the information that medical data should be treated with low prejudice, providing developers and researchers with insight into the real-world context in which clinicians are embracing medical artificial intelligence.

Brain Tumour Classification Using Noble Deep Learning Approach with Parametric Optimization through Metaheuristics Approaches

Deep learning has surged in popularity in recent years, notably in the domains of medical image processing, medical image analysis, and bioinformatics. In this study, we offer a completely autonomous brain tumour segmentation approach based on deep neural networks (DNNs). We describe a unique CNN architecture which varies from those usually used in computer vision. The classification of tumour cells is very difficult due to their heterogeneous nature. From a visual learning and brain tumour recognition point of view, a convolutional neural network (CNN) is the most extensively used machine learning algorithm. This paper presents a CNN model along with parametric optimization approaches for analysing brain tumour magnetic resonance images. The accuracy percentage in the simulation of the above-mentioned model is exactly 100% throughout the nine runs, i.e., Taguchi’s L9 design of experiment. This comparative analysis of all three algorithms will pique the interest of readers who are interested in applying these techniques to a variety of technical and medical challenges. In this work, the authors have tuned the parameters of the convolutional neural network approach, which is applied to the dataset of Brain MRIs to detect any portion of a tumour, through new advanced optimization techniques, i.e., SFOA, FBIA and MGA.