Metastatic testicular cancer and extragonadal germ cell tumor presenting with neurological symptoms

1990 ◽  
Vol 8 (2) ◽  
Author(s):  
Nina Borge ◽  
SophieD. Foss� ◽  
AnnaElisabeth Stenwig
Author(s):  
Michael Risk

This chapter reviews a pivotal, single-armed observational study of consecutive patients with metastatic testicular germ cell tumor treated with a combination of bleomycin, vinblastine, and cisplatin. This study established that cisplatin-based combination chemotherapy resulted in a much better prognosis in patients with metastatic testicular cancer than historically observed with any other treatment and also resulted in high response rates.


2017 ◽  
Vol 11 (2) ◽  
pp. 110-112
Author(s):  
Umar Karaman ◽  
Faye B. Serkin ◽  
Jennifer M. Taylor ◽  
Michael Constantinescu

Testicular yolk sac tumor (YST) is a nonseminomatous germ cell tumor that predominantly affects prepubescent boys. Pure endometrioid variant YST is rare, with only 1 report in the literature. We present the first reported case of en-dometrioid variant YST with mature teratoma in the retro-peritoneal specimen.


2006 ◽  
Vol 36 (11) ◽  
pp. 723-730 ◽  
Author(s):  
Koji Kawai ◽  
Shiro Hinotsu ◽  
Takehiro Oikawa ◽  
Noritoshi Sekido ◽  
Kazunori Hattori ◽  
...  

1995 ◽  
Vol 55 (1) ◽  
pp. 44-45 ◽  
Author(s):  
L.Y. Dirix ◽  
E. Wouters ◽  
J. van Nueten ◽  
W. van Eerdeweg ◽  
A.T. van Oosterom

2016 ◽  
Vol 10 (1) ◽  
pp. 198-203 ◽  
Author(s):  
Koji Komori ◽  
Daisuke  Takahari ◽  
Kenya Kimura ◽  
Takashi Kinoshita ◽  
Seiji Ito ◽  
...  

A germ cell tumor is the most common form of malignancy in early male life, and can be classified as either seminomatous or nonseminomatous. Choriocarcinoma, comprised of nonseminomatous germ cells, is the most aggressive type of germ cell tumor and characteristically metastasizes to the retroperitoneal lymph nodes and less frequently to the lungs, liver, bone or brain [Shibuya et al., 2009;48: 551–554]. A 56-year-old man was admitted to another hospital complaining of abdominal distension. Symptoms included anorexia, vomiting, and diarrhea. The patient was diagnosed with an extragonadal germ cell tumor and referred to our hospital to receive chemotherapy. The day after admission, the patient’s abdominal distension gradually worsened. An emergency operation revealed venous hemorrhage from the surface of a metastatic extragonadal germ cell tumor between the ligament of Treitz and the inferior mesenteric vein in a horizontal position. Hemostatic treatment was performed with 4-0 proline thread attached to a medicated cotton sponge, rather than using a simple proline thread, and the closure area was manually compressed. Chemotherapy was initiated on postoperative day 10. A metastatic extragonadal germ cell tumor that causes massive hemorrhage and gastrointestinal hemorrhage is very rare, and represents a life-threatening emergency. If the patient’s condition carries a substantial risk of bleeding to death, it may be worthwhile to attempt abdominal operations.


2011 ◽  
Vol 6 (1) ◽  
pp. 32-34
Author(s):  
Yoshinobu Moritoki ◽  
Toshiki Kato ◽  
Hidenori Nishio ◽  
Hideyuki Kamisawa ◽  
Yasuhiko Hirose ◽  
...  

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