The microcirculation in neodymion-YAG laser irradiated and in electro coagulated urinary bladder tumors evaluated with laser Doppler flowmetry

1986 ◽  
Vol 14 (3) ◽  
Author(s):  
H.O. Beisland ◽  
K. Kvernebo
2012 ◽  
Vol 93 (1) ◽  
pp. 68-72
Author(s):  
A I Neymark ◽  
M V Razdorskaya ◽  
K A Sizov

Aim. To assess the dynamics of the microcirculation indices in the mucous layer of the urinary bladder on the background of conservative treatment of women with urination disorders. Methods. Examined were 40 women with complaints of urination disorders, who were repeatedly treated regarding this reason. 20 female patients who underwent standard complex conservative therapy represented the first group. The second group included 20 patients who in addition received an α1-adrenergic blocker terazosin in a dose 2 mg at night. The course of treatment ranged from 1 to 3 months. Results. 9 (45%) women of the first group and 16 (80%) patients of the second group observed a positive effect of the treatment. In the patients of the second group registered was a more rapid normalization of clinical signs and indicators of laser Doppler flowmetry: an increase in neurogenic tone in precapillaries, in the bypass index and in the index of effectiveness of microcirculation, an increase in the microcirculation parameter and in the coefficient of variation, which indicates an improvement in the microhemocirculation. Conclusion. The study of blood flow through the capillary vascular bed by laser Doppler flowmetry makes it possible to study the microcirculation in the mucosa of the urinary bladder wall in order to monitor the effectiveness of the conducted therapy.


VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 243-249 ◽  
Author(s):  
Drinda ◽  
Neumann ◽  
Pöhlmann ◽  
Vogelsang ◽  
Stein ◽  
...  

Background: Prostanoids are used in the treatment of Raynaud’s phenomenon and acral perfusion disorders secondary to collagenosis. In subjective terms, intravenous administration of these agents produces success in more than 50% of patients. The therapeutic outcome of clinical administration of alprostadil or iloprost may vary from individual to individual. Patients and methods: The following variables were analysed in a cross-over study in 27 patients with collagenosis and Raynaud’s phenomenon: plasma viscosity and erythrocyte aggregation (rheological variables), partial pressure of oxygen and laser Doppler flowmetry in the finger region, and lymphocyte phenotyping and interleukin (IL) determinations (immunological variables). Results: Laser Doppler flowmetry revealed significant differences between patients with secondary Raynaud’s phenomenon and a control group of 25 healthy subjects. Laser Doppler readings did not change significantly as a result of the treatments. Therapy with iloprost produced a reduction in IL-1beta, L-selectin (CD 62 L) and IL-6. Conclusion: The change in immunological variables due to iloprost may explain the long-term effects of prostaglandins in the treatment of Raynaud’s phenomenon. From our results it is not possible to infer any preference for iloprost or alprostadil.


Author(s):  
A. N. Kuks ◽  
N. V. Slivnitsyna

The results of laser Doppler flowmetry in patients with vibration disease associated with the combined effects of local and general vibration with a history of type 2 diabetes are presented.


2019 ◽  
Vol 24 (2) ◽  
pp. 108-119 ◽  
Author(s):  
B. N. Davydov ◽  
D. A. Domenyuk ◽  
S. V. Dmitrienko

Relevance. Morpho-functional changes in peripheral circulation established in type 1 diabetes mellitus correlate with changes in central hemodynamics, allowing the use of microcirculation indicators as diagnostic and prognostic criteria for assessing the degree of functional vascular disorders. Identifcation of microcirculation features of the blood by the method of laser Doppler flowmetry in children with different experience of type 1 diabetes in key age categories.Materials and methods. The study included 67 children with type 1 diabetes mellitus aged 12-15 years with an experience of the disease from six months to ten years. The comparison group consisted of 38 healthy children. The state of the microvasculature was assessed by laser Doppler flowmetry using a laser analyzer for capillary blood flow LAKK-OP.Results. In children with an experience of type 1 diabetes of less than two years, microcirculation disorders in periodontal tissues correspond to the hyperemic form, accompanied by increased perfusion, a decrease in the amplitude of low-frequency oscillations, increased heart rate, high blood flling, and blood flow bypass. For children with an endocrinopathy experience of more than three years, microcirculation disorders correspond to a stagnant form, combined with a decrease in perfusion due to stagnation of blood in the venular link, endothelial domination with suppression of neurogenic and cardiac fluctuations, low efciency and redistribution of blood flow in favor of the nutritive link.Conclusions. With the increase in experience, the degree of compensation of type 1 diabetes, the progression of diabetic microangiopathy, it is advisable to designate two stages of development of microcirculatory disorders. Early – compensatory with active adaptation, including neurogenic and endothelial regulation mechanisms. Late – decompensation with passive adaptation, supporting the effectiveness of microcirculation due to myogenic control of regulation, shunting and increasing the rate of blood outflow.


2017 ◽  
Vol 10 (2) ◽  
pp. 62-66 ◽  
Author(s):  
T.N. Safonova ◽  
◽  
N.P. Kintyukhina ◽  
V.V. Sidorov ◽  
O.V. Gladkova ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document