?Epi-? and intramedullary neurilemmoma of the spinal cord with denervation atrophy in the related skeletal muscles

1975 ◽  
Vol 209 (4) ◽  
pp. 271-278 ◽  
Author(s):  
Horst P. Schmitt
1950 ◽  
Vol 92 (2) ◽  
pp. 169-190 ◽  
Author(s):  
Alwin M. Pappenheimer ◽  
Joan B. Daniels ◽  
F. S. Cheever ◽  
T. H. Weller

A study has been made of the lesions produced in suckling mice by the following viruses: Powers, Matulaitis, DeMole, Kine, McCarthy, Conn. 5, Ohio R, High Point, WS No. 4, EMC, and Col. SK. Pathologic alterations have been found in myocardium, lungs, liver, pancreas, thymus, brain and spinal cord, adipose tissue, and skeletal muscles. A comparison of the lesions produced by the individual strains has disclosed certain differential features which are discussed in detail. Within the group of so called Coxsackie viruses, myositis has not proved to be a constant finding, and it may occur in suckling mice infected with other types of virus.


2017 ◽  
Vol 78 (2) ◽  
pp. 217-223
Author(s):  
A. Kroth ◽  
V. Mackedanz ◽  
C. Matté ◽  
A. T. S. Wyse ◽  
M. F. M. Ribeiro ◽  
...  

Abstract Sciatic nerve transection (SNT), a model for studying neuropathic pain, mimics the clinical symptoms of “phantom limb”, a pain condition that arises in humans after amputation or transverse spinal lesions. In some vertebrate tissues, this condition decreases acetylcholinesterase (AChE) activity, the enzyme responsible for fast hydrolysis of released acetylcholine in cholinergic synapses. In spinal cord of frog Rana pipiens, this enzyme’s activity was not significantly changed in the first days following ventral root transection, another model for studying neuropathic pain. An answerable question is whether SNT decreases AChE activity in spinal cord of frog Lithobates catesbeianus, a species that has been used as a model for studying SNT-induced neuropathic pain. Since each animal model has been created with a specific methodology, and the findings tend to vary widely with slight changes in the method used to induce pain, our study assessed AChE activity 3 and 10 days after complete SNT in lumbosacral spinal cord of adult male bullfrog Lithobates catesbeianus. Because there are time scale differences of motor endplate maturation in rat skeletal muscles, our study also measured the AChE activity in bullfrog tibial posticus (a postural muscle) and gastrocnemius (a typical skeletal muscle that is frequently used to study the motor system) muscles. AChE activity did not show significant changes 3 and 10 days following SNT in spinal cord. Also, no significant change occurred in AChE activity in tibial posticus and gastrocnemius muscles at day 3. However, a significant decrease was found at day 10, with reductions of 18% and 20% in tibial posticus and gastrocnemius, respectively. At present we cannot explain this change in AChE activity. While temporally different, the direction of the change was similar to that described for rats. This similarity indicates that bullfrog is a valid model for investigating AChE activity following SNT.


1979 ◽  
Vol 16 (1) ◽  
pp. 49-59 ◽  
Author(s):  
R. Bradley ◽  
F. D. Kirby

A full term Friesian bull calf was born unable to stand. The dam had no signs of illness during pregnancy. In the thoracic spinal cord there was anomalous development of the central canal and a dorsally placed fusiform and longitudinal dilatation. Mild inflammatory lesions were seen in some body organs and central nervous system where they were suggestive of viral infection. Several skeletal muscles had an extended range of muscle cell cross sectional areas and some cells had numerous internal nuclei.


1954 ◽  
Vol 178 (3) ◽  
pp. 535-537 ◽  
Author(s):  
D. C. Sutfin ◽  
J. D. Thomson ◽  
H. M. Hines

1897 ◽  
Vol 60 (359-367) ◽  
pp. 411-414 ◽  
Keyword(s):  

A phenomenon came under my observation in the course of experiments upon monkeys a t the commencement of the present year which seems sufficiently interesting to merit record here. Its occurrence, so long as certain conditions of experiment are maintained, appears regular and predictable. Although the character of the movements executed by the skeletal muscles w hen excited reflexly through the medium of the isolated spinal cord is variable, one feature common to them is their comparative brevity of duration.


Author(s):  
Tufia C. Haddad ◽  
Timothy J. Moynihan

Diseases affecting the spinal cord, peripheral nerves, and skeletal muscles are common in clinical practice. These conditions may present in isolation or as an associated feature (or complication) of nonneurologic disease. The clinical history and examination provide the greatest usefulness for establishing the diagnosis, which can be firmly established with diagnostic testing. Electrodiagnostic tests (nerve conduction studies and electromyography) are among the most useful in patients with nerve or muscle disease. Treatments are targeted to the underlying mechanism of disease.


2014 ◽  
Vol 50 (4) ◽  
pp. 599-601 ◽  
Author(s):  
Ceren Yarar-Fisher ◽  
C. Scott Bickel ◽  
Neil A. Kelly ◽  
Samuel T. Windham ◽  
Amie B. Mclain ◽  
...  

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