Ethylene production by shoot-forming and unorganized crown-gall tumor tissues of Nicotiana and Lycopersicon cultured in vitro

Planta ◽  
1984 ◽  
Vol 161 (5) ◽  
pp. 418-424 ◽  
Author(s):  
A. Raymond Miller ◽  
William L. Pengelly
PROTOPLASMA ◽  
1959 ◽  
Vol 52 (1) ◽  
pp. 143-144
Author(s):  
W. A. Kurt Schmidt
Keyword(s):  

1983 ◽  
Vol 2 (6) ◽  
pp. 321-333 ◽  
Author(s):  
G. M. S. van Slogteren ◽  
J. H. C. Hoge ◽  
P. J. J. Hooykaas ◽  
R. A. Schilperoort

Science ◽  
1986 ◽  
Vol 231 (4738) ◽  
pp. 616-618 ◽  
Author(s):  
M. Thomashow ◽  
S Hugly ◽  
W. Buchholz ◽  
L. Thomashow

2020 ◽  
Author(s):  
Sandeep Waghulde ◽  
Tushar Baviskar ◽  
Praful Patil ◽  
Shweta Singh ◽  
Nilesh Gorde ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3532
Author(s):  
Ibrahim M. El-Deeb ◽  
Valeria Pittala ◽  
Diab Eltayeb ◽  
Khaled Greish

Triple-negative breast cancer (TNBC) is a heterogeneous subtype of tumors that tests negative for estrogen receptors, progesterone receptors, and excess HER2 protein. The mainstay of treatment remains chemotherapy, but the therapeutic outcome remains inadequate. This paper investigates the potential of a duocarmycin derivative, tafuramycin A (TFA), as a new and more effective chemotherapy agent in TNBC treatment. To this extent, we optimized the chemical synthesis of TFA, and we encapsulated TFA in a micellar system to reduce side effects and increase tumor accumulation. In vitro and in vivo studies suggest that both TFA and SMA–TFA possess high anticancer effects in TNBC models. Finally, the encapsulation of TFA offered a preferential avenue to tumor accumulation by increasing its concentration at the tumor tissues by around four times in comparison with the free drug. Overall, the results provide a new potential strategy useful for TNBC treatment.


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