Localization of viral DNA-replication in sections of human warts by nucleic acid hybridization with complementary RNA of human papilloma virus type 1

1979 ◽  
Vol 264 (1) ◽  
pp. 55-63 ◽  
Author(s):  
Elke-Ingrid Grußendorf ◽  
Harald zur Hausen
Keyword(s):  
Dna Replication ◽  
Nucleic Acid ◽  
Human Papilloma Virus ◽  
Virus Type ◽  
Nucleic Acid Hybridization ◽  
Human Papilloma Virus Type ◽  
Viral Dna ◽  
Viral Dna Replication ◽  
Papilloma Virus

scholarly journals The UL15 protein of herpes simplex virus type 1 is necessary for the localization of the UL28 and UL33 proteins to viral DNA replication centres

2008 ◽  
Vol 89 (7) ◽  
pp. 1709-1715 ◽  
Author(s):  
Martin R. Higgs ◽  
Valerie G. Preston ◽  
Nigel D. Stow
Keyword(s):  
Herpes Simplex Virus ◽  
Dna Replication ◽  
Herpes Simplex ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Viral Dna ◽  
Viral Dna Replication ◽  
Simplex Virus ◽  
Hsv 1

The UL15, UL28 and UL33 proteins of herpes simplex virus type 1 (HSV-1) are thought to comprise a terminase complex responsible for cleavage and packaging of the viral genome into pre-assembled capsids. Immunofluorescence studies confirmed that shortly after infection with wild-type HSV-1 these three proteins localize to viral DNA replication compartments within the nucleus, identified by the presence of the single-stranded DNA-binding protein, ICP8. In cells infected with either UL28- or UL33-null mutants, the other two terminase proteins also co-localized with ICP8. In contrast, neither UL28 nor UL33 was detectable in replication compartments following infection with a UL15-null mutant, although Western blot analysis showed they were present in normal amounts in the infected cells. Provision of UL15 in a complementing cell line restored the ability of all three proteins to localize to replication compartments. These data indicate that UL15 plays a key role in localizing the terminase complex to DNA replication compartments, and that it can interact independently with UL28 and UL33.

scholarly journals Binding of the herpes simplex virus type 1 UL9 gene product to an origin of viral DNA replication

1989 ◽  
Vol 17 (4) ◽  
pp. 1409-1425 ◽  
Author(s):  
Hazel M. Weir ◽  
Janice M. Calder ◽  
Nigel D. Stow
Keyword(s):  
Herpes Simplex Virus ◽  
Dna Replication ◽  
Herpes Simplex ◽  
Gene Product ◽  
Virus Type ◽  
Herpes Simplex Virus Type ◽  
Viral Dna ◽  
Viral Dna Replication ◽  
Simplex Virus

BLADDER SQUAMOUS CELL CARCINOMA WITH HUMAN PAPILLOMA VIRUS TYPE 6 [HPV 6]

1995 ◽  
Vol 2 (5) ◽  
pp. 347-349
Author(s):  
Hiroyuki Tatsura ◽  
Yoshihiko Ishiguro ◽  
Takehiko Okamura ◽  
Kenjiro Kohri
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papilloma Virus ◽  
Cell Carcinoma ◽  
Virus Type ◽  
Squamous Cell ◽  
Human Papilloma Virus Type ◽  
Papilloma Virus

In situ Localization of Human Papilloma Virus Type 16 DNA in a Metastasis of an Endocervical Adenocarcinoma

Intervirology ◽  
1987 ◽  
Vol 27 (2) ◽  
pp. 81-85 ◽  
Author(s):  
Jan M.M. Walboomers ◽  
Hendrik E. Fokke ◽  
Mirjam Polak ◽  
Herman Volkers ◽  
Hendrik Jan Houthoff ◽  
...  
Keyword(s):  
Human Papilloma Virus ◽  
Virus Type ◽  
Human Papilloma Virus Type ◽  
Papilloma Virus ◽  
Endocervical Adenocarcinoma
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