Recombinant inbred strains, their progenitor strains, and their reciprocal F1 hybrids were tested for maze learning in the Lashley III maze and in the Y-water maze. The resulting pattern of strain distribution suggested that the genetic model provided by the RI strains is based on at least two, and possibly many more, loci. There was no evidence of maternal effects or heterosis. Although the BALB/cBy strain represented an extremely high scoring strain for the Lashley maze and a low scoring strain for the Y-maze, presence of albino recombinant inbred strains intermediate to extreme strains and nonsignificantly different from pigmented recombinant inbred strains suggested that the albino gene was not responsible for the observed performance differences.