Effect of certain antiadrenergic agents on systolic time intervals in essential hypertension

1977 ◽  
Vol 11 (6) ◽  
pp. 423-427 ◽  
Author(s):  
E. Q. Roland ◽  
M. E. Safar ◽  
Cl. E. Lelguen ◽  
N. E. Aboras ◽  
Y. A. Weiss ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Systolic Time Intervals ◽  
Time Intervals ◽  
Systolic Time

Circulating Catecholamines and Systolic Time Intervals in Labile and Sustained Hypertension

1978 ◽  
Vol 55 (s4) ◽  
pp. 65s-68s ◽  
Author(s):  
D. Cousineau ◽  
J. de Champlain ◽  
L. Lapointe
Keyword(s):  
Heart Rate ◽  
Essential Hypertension ◽  
Myocardial Contractility ◽  
Systolic Time Intervals ◽  
Normal Range ◽  
Time Intervals ◽  
Hypertensive Patients ◽  
Sustained Hypertension ◽  
Systolic Time ◽  
Hypotensive Response

1. Average supine circulating total catecholamine concentrations were found to be higher than the normal range in about 50% of patients with labile hypertension and in about 30% of patients with sustained essential hypertension. 2. These higher resting concentrations were mainly due to an increase in adrenaline in labile hypertension and to an increase in noradrenaline in sustained hypertension. 3. Patients with elevated catecholamine concentrations were also characterized by a higher heart rate, by an increased myocardial contractility and by greater hypotensive response after treatment with β-adrenoreceptor blocking agents. 4. These studies suggest the existence of subgroups of hypertensive patients with increased sympathetic tone.

The Antihypertensive Effects of Ketanserin (R 41 468), a Novel 5-Hydroxytryptamine-Blocking Agent, in Patients with Essential Hypertension

1981 ◽  
Vol 61 (s7) ◽  
pp. 473s-476s ◽  
Author(s):  
J. De Crée ◽  
J. Leempoels ◽  
H. Geukens ◽  
W. De Cock ◽  
H. Verhaegen
Keyword(s):  
Essential Hypertension ◽  
High Selectivity ◽  
Systolic Time Intervals ◽  
Blocking Agent ◽  
Time Intervals ◽  
Double Blind ◽  
Venous Capacitance ◽  
Systolic Time ◽  
5Ht2 Receptor ◽  
Observation Period

1. In a double-blind placebo-controlled crossover study a 4 week treatment with ketanserin was shown to reduce systolic and diastolic blood pressure markedly and significantly in 10 patients with essential hypertension. Heart rate remained virtually unchanged during the whole observation period. Systolic time intervals, reflecting cardiac output, did not change during the ketanserin phase, whereas these values deteriorated during the placebo period. 2. Ketanserin, a novel 5-hydroxytryptamine (5HT2)-receptor antagonist with a high selectivity for blood vessels and thrombocytes, most probably acts by decreasing the venous capacitance bed constriction, and by counteraction of the amplifying effects of serotonin on noradrenaline and other vasoactive amines.

scholarly journals Noninvasive evaluation of left ventricular function by systolic time intervals in essential hypertension with angina pectoris.

1984 ◽  
Vol 48 (12) ◽  
pp. 1299-1305 ◽  
Author(s):  
TAKAAKI OCHI ◽  
MAREOMI HAMADA ◽  
YUKIO KAZATANI ◽  
YUJI SHIGEMATSU ◽  
MICHIHITO SEKITA ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Angina Pectoris ◽  
Left Ventricular Function ◽  
Ventricular Function ◽  
Systolic Time Intervals ◽  
Left Ventricular ◽  
Noninvasive Evaluation ◽  
Time Intervals ◽  
Systolic Time

Systolic Time Intervals and Hydralazine

CHEST Journal ◽  
1982 ◽  
Vol 81 (5) ◽  
pp. 660 ◽  
Author(s):  
George Louridas ◽  
Demetrios Patakas ◽  
Nicholas Galanis ◽  
Marianna Kakoura ◽  
Costas Stavropoulos
Keyword(s):  
Systolic Time Intervals ◽  
Time Intervals ◽  
Systolic Time

scholarly journals Reliability of systolic time intervals in diagnosis of transposition of great arteries in newborn.

Heart ◽  
1981 ◽  
Vol 46 (1) ◽  
pp. 74-79 ◽  
Author(s):  
G G Sandor ◽  
M W Patterson ◽  
M Tipple ◽  
D J Vince
Keyword(s):  
Systolic Time Intervals ◽  
Time Intervals ◽  
Transposition Of Great Arteries ◽  
Systolic Time

scholarly journals Alteration of Systolic Time Intervals in Right Ventricular Failure

Circulation ◽  
1974 ◽  
Vol 50 (2) ◽  
pp. 317-323 ◽  
Author(s):  
JOSEPH S. ALPERT ◽  
FRANK D. RICKMAN ◽  
JOHN P. HOWE ◽  
LEWIS DEXTER ◽  
JAMES E. DALEN
Keyword(s):  
Right Ventricular ◽  
Systolic Time Intervals ◽  
Right Ventricular Failure ◽  
Ventricular Failure ◽  
Time Intervals ◽  
Systolic Time
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