Force-velocity-length relationship in heart muscle: Lack of time-independence during twitch contractions of frog ventricle strips with caffeine

1974 ◽  
Vol 348 (1) ◽  
pp. 59-64 ◽  
Author(s):  
Andrew H. Henderson ◽  
Dirk L. Brutsaert
1983 ◽  
pp. 87-95 ◽  
Author(s):  
Y. Lecarpentier ◽  
P. Gastineau ◽  
P. Y. Hatt ◽  
J. L. Martin

2020 ◽  
Vol 129 (3) ◽  
pp. 569-579
Author(s):  
Robin Hager ◽  
Thomas Poulard ◽  
Antoine Nordez ◽  
Sylvain Dorel ◽  
Gaël Guilhem

Ankle angle influences the operating muscle fascicle lengths of gastrocnemius medialis and the rate of torque development during explosive isometric plantar flexions. The rate of torque development peaks in neutral angles where muscle fascicles shorten over the plateau of the force-length relationship. When fascicles operate over the plateau of the force-length relationship (neutral ankle positions), the force-velocity properties represent a limiting factor for the rapid force-generating capacity from 100 ms after the onset of explosive contractions.


1960 ◽  
Vol 198 (1) ◽  
pp. 89-93 ◽  
Author(s):  
Sidney S. Schreiber ◽  
Murray Oratz ◽  
Marcus A. Rothschild

Potassium in the working frog ventricle exists in two physiological compartments and the more slowly exchanging compartment is influenced by the amount of work performed, ventricular failure and ouabain. In the present study, the exchange of potassium in mitochondria is investigated both in the control state and after exposure to ouabain, in order to determine whether mitochondria potassium represents the slowly exchanging compartment. Mitochondria potassium represents only 15% of the total ventricular potassium, while the slowly exchanging phase contains about 50%. Ouabain perfusion is associated with inhibition of entrance of potassium into the slowly exchanging ventricular phase, but no isolated specific effect on the mitochondria potassium is found. Alterations in mitochondria potassium directly reflect changes within the total ventricle. A fraction of mitochondria potassium is found to be inexchangeable under the conditions of the experiment. The results indicate that mitochondria potassium does not represent the major part of the slowly exchanging compartment.


1973 ◽  
Vol 32 (3) ◽  
pp. 385-392 ◽  
Author(s):  
DIRK L. BRUTSAERT ◽  
VICTOR A. CLAES ◽  
MARK A. GOETHALS
Keyword(s):  

1969 ◽  
Vol 24 (2) ◽  
pp. 137-149 ◽  
Author(s):  
DIRK L. BRUTSAERT ◽  
Edmund H. Sonnenblick
Keyword(s):  

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