Force-Velocity-Length Relationship during Cardiac Hypertrophy

1983 ◽  
pp. 87-95 ◽  
Author(s):  
Y. Lecarpentier ◽  
P. Gastineau ◽  
P. Y. Hatt ◽  
J. L. Martin
Keyword(s):  
Cardiac Hypertrophy ◽  
Length Relationship ◽  
Force Velocity

scholarly journals Influence of joint angle on muscle fascicle dynamics and rate of torque development during isometric explosive contractions

2020 ◽  
Vol 129 (3) ◽  
pp. 569-579
Author(s):  
Robin Hager ◽  
Thomas Poulard ◽  
Antoine Nordez ◽  
Sylvain Dorel ◽  
Gaël Guilhem
Keyword(s):  
Joint Angle ◽  
Limiting Factor ◽  
Gastrocnemius Medialis ◽  
Rate Of Torque Development ◽  
Muscle Fascicle ◽  
Length Relationship ◽  
Ankle Angle ◽  
Generating Capacity ◽  
Force Velocity ◽  
Torque Development

Ankle angle influences the operating muscle fascicle lengths of gastrocnemius medialis and the rate of torque development during explosive isometric plantar flexions. The rate of torque development peaks in neutral angles where muscle fascicles shorten over the plateau of the force-length relationship. When fascicles operate over the plateau of the force-length relationship (neutral ankle positions), the force-velocity properties represent a limiting factor for the rapid force-generating capacity from 100 ms after the onset of explosive contractions.

scholarly journals Instantaneous force-velocity-length relationship in diaphragmatic sarcomere

1997 ◽  
Vol 82 (2) ◽  
pp. 404-412 ◽  
Author(s):  
Catherine Coirault ◽  
Denis Chemla ◽  
Jean-Claude Pourny ◽  
Francine Lambert ◽  
Yves Lecarpentier
Keyword(s):  
Mechanical Properties ◽  
Striated Muscle ◽  
Mechanical Performance ◽  
Three Dimensional ◽  
Muscle Length ◽  
Total Load ◽  
Length Relationship ◽  
Abrupt Changes ◽  
Force Velocity ◽  
Isometric Twitch

Coirault, Catherine, Denis Chemla, Jean-Claude Pourny, Francine Lambert, and Yves Lecarpentier. Instantaneous force-velocity-length relationship in diaphragmatic sarcomere. J. Appl. Physiol. 82(2): 404–412, 1997.—The simultaneous analysis of muscle force, length, velocity, and time has been shown to precisely characterize the mechanical performance of isolated striated muscle. We tested the hypothesis that the three-dimensional force-velocity-length relationship reflects mechanical properties of sarcomeres. In hamster diaphragm strips, instantaneous sarcomere length (S L) and muscle length were simultaneously measured during afterloaded twitches. S L was measured by means of laser diffraction. We also studied the influence of initial S L, abrupt changes in total load, and 2 × 10−7 M dantrolene. Baseline resting S L at the apex of the length-active tension curve was 2.2 ± 0.1 μm, whereas S L at peak shortening was 1.6 ± 0.1 μm in the preloaded twitch and 2.1 ± 0.1 μm in the “isometric” twitch. Over the whole load continuum and at any given level of isotonic load, there was a unique relationship between instantaneous sarcomere velocity and instantaneous S L. Part of this relationship was time independent and initial S L independent and was markedly downshifted after dantrolene. When five different muscle regions were considered, there were no significant variations of S L and sarcomere kinetics along the muscle. These results indicate that the time- and initial length-independent part of the instantaneous force-velocity-length relationship previously described in muscle strips reflects intrinsic sarcomere mechanical properties.

421 The NFATc2 isoform plays a major role in calcineurin-induced cardiac hypertrophy

2006 ◽  
Vol 5 (1) ◽  
pp. 98-98
Author(s):  
M BOURAJJAJ ◽  
A ARMAND ◽  
B WEIJTS ◽  
L DEWINDT
Keyword(s):  
Cardiac Hypertrophy

Sex differences in cardiac hypertrophy are linked to adipose tissue lipolysis

2011 ◽  
Vol 6 (S 01) ◽  
Author(s):  
A Foryst-Ludwig ◽  
M Kreissl ◽  
C Sprang ◽  
B Thalke ◽  
C Böhm ◽  
...  
Keyword(s):  
Sex Differences ◽  
Adipose Tissue ◽  
Cardiac Hypertrophy ◽  
Adipose Tissue Lipolysis
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