Tissue cultivation of rose-colored periwinkle. Biosynthesis of indole alkaloids

1978 ◽  
Vol 12 (8) ◽  
pp. 1048-1050
Author(s):  
T. I. Andreeva ◽  
L. N. Bereznegovskaya ◽  
A. V. Smorodin
Keyword(s):  
Indole Alkaloids ◽  
Tissue Cultivation

Monoterpene indole alkaloids from the leaves of Tabernaemontana elegans induce apoptosis activity in human hepatoma cells

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
TA Mansoor ◽  
RM Ramalho ◽  
CMP Rodrigues ◽  
S Mulhovo ◽  
MJU Ferreira
Keyword(s):  
Indole Alkaloids ◽  
Hepatoma Cells ◽  
Human Hepatoma ◽  
Human Hepatoma Cells ◽  
Monoterpene Indole Alkaloids

Indole alkaloids from Duroia macrophylla (Rubiaceae)

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
CV Nunez ◽  
V Roumy ◽  
DWO Mesquita ◽  
ASS Mesquita ◽  
S Sahpaz ◽  
...  
Keyword(s):  
Indole Alkaloids

Apoptosis inducing activity of hydrazone derivatives of monoterpene indole alkaloids in human colon (HCT116) and liver (HepG2) carcinoma cells

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
A Paterna ◽  
PM Borralho ◽  
SE Gomes ◽  
S Mulhovo ◽  
CMP Rodrigues ◽  
...  
Keyword(s):  
Indole Alkaloids ◽  
Human Colon ◽  
Carcinoma Cells ◽  
Monoterpene Indole Alkaloids ◽  
Derivatives Of

Indole alkaloids from plants: Novel structures, bioactivities and preclinical investigations

Planta Medica ◽  
2015 ◽  
Vol 81 (05) ◽  
Author(s):  
XH Cai ◽  
T Feng ◽  
XN Li ◽  
YP Liu ◽  
JH Shang ◽  
...  
Keyword(s):  
Indole Alkaloids ◽  
Novel Structures

A novel class of indole alkaloids isolated from Flindersia pimenteliana (Rutaceae)

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
LP Robertson ◽  
S Duffy ◽  
VM Avery ◽  
AR Carroll
Keyword(s):  
Indole Alkaloids

Dehydrogenation studies in the field of indole alkaloids

1957 ◽  
Author(s):  
Dilip Kumar Roychaudhuri
Keyword(s):  
Indole Alkaloids

Chemical transformations in the field of indole alkaloids

1962 ◽  
Author(s):  
Robert Lin Sung Amai
Keyword(s):  
Indole Alkaloids ◽  
Chemical Transformations

Antimicrobial, Antineoplastic and Cytotoxic Activities of Indole Alkaloids from Tabernaemontana divaricata (L.) R.Br.

2011 ◽  
Vol 7 (2) ◽  
pp. 125-132 ◽  
Author(s):  
Bharat Singh ◽  
Ram A. Sharma ◽  
Govind K. Vyas
Keyword(s):  
Indole Alkaloids ◽  
Cytotoxic Activities ◽  
Tabernaemontana Divaricata

Isolation and Characterization Procedure for Indole Alkaloids from the Marquesan Plant Rauvolfia Nukuhivensis

BIO-PROTOCOL ◽  
2015 ◽  
Vol 5 (20) ◽  
Author(s):  
Nicolas Martin ◽  
Ma�l Nicolas ◽  
Ga�l Lecellier ◽  
Phila Raharivelomanana
Keyword(s):  
Indole Alkaloids ◽  
Isolation And Characterization ◽  
Characterization Procedure

scholarly journals Chemical Diversity and Bioactivities of Monoterpene Indole Alkaloids (MIAs) from Six Apocynaceae Genera

Molecules ◽  
2021 ◽  
Vol 26 (2) ◽  
pp. 488
Author(s):  
Afrah E. Mohammed ◽  
Zainab H. Abdul-Hameed ◽  
Modhi O. Alotaibi ◽  
Nahed O. Bawakid ◽  
Tariq R. Sobahi ◽  
...  
Keyword(s):  
Biological Activities ◽  
Indole Alkaloids ◽  
Natural Compounds ◽  
Molecular Target ◽  
Chemical Diversity ◽  
Drug Lead ◽  
The Family ◽  
Monoterpene Indole Alkaloids ◽  
Drug Leads ◽  
Anti Hiv

By the end of the twentieth century, the interest in natural compounds as probable sources of drugs has declined and was replaced by other strategies such as molecular target-based drug discovery. However, in the recent times, natural compounds regained their position as extremely important source drug leads. Indole-containing compounds are under clinical use which includes vinblastine and vincristine (anticancer), atevirdine (anti-HIV), yohimbine (erectile dysfunction), reserpine (antihypertension), ajmalicine (vascular disorders), ajmaline (anti-arrhythmic), vincamine (vasodilator), etc. Monoterpene Indole Alkaloids (MIAs) deserve the curiosity and attention of researchers due to their chemical diversity and biological activities. These compounds were considered as an impending source of drug-lead. In this review 444 compounds, were identified from six genera belonging to the family Apocynaceae, will be discussed. These genera (Alstonia, Rauvolfia, Kopsia, Ervatamia, and Tabernaemontana, and Rhazya) consist of 400 members and represent 20% of Apocynaceae species. Only 30 (7.5%) species were investigated, whereas the rest are promising to be investigated. Eleven bioactivities, including antibacterial, antifungal, anti-inflammatory and immunosuppressant activities, were reported. Whereas cytotoxic effect represents 47% of the reported activities. Convincingly, the genera selected in this review are a wealthy source for future anticancer drug lead.

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