Role of nucleic acid synthesis in the mechanism of the stabilization of conditioned reflexes and memory

1965 ◽  
Vol 60 (6) ◽  
pp. 1347-1350
Author(s):  
F. Z. Meerson ◽  
R. I. Kruglikov ◽  
I. A. Kolomeitseva
1959 ◽  
Vol 234 (3) ◽  
pp. 625-627
Author(s):  
Ranjan Mehta ◽  
David A. Vaughan ◽  
Shreepad R. Wagle ◽  
Kendall D. Barbee ◽  
S.P. Mistry ◽  
...  

Living cells grown in tissue culture have been irradiated with a narrow beam of soft X-rays of effective diameter 2·5 μ. The method has been used in conjunction with quantitative ultra-violet photomicrography to investigate the role of the nucleolus in nucleic acid synthesis. The results show that X-irradiation of the nucleolus reduces the amount of nucleic acid synthesized in the nucleus when measured 3 to 7 h after irradiation, whereas X-irradiation of the nuclear sap with an equal dose does not show this effect. The significance of this is discussed.


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