Elevation of the panting threshold of the desert iguana,Dipsosaurus dorsalis, during dehydration: Potential roles of changes in plasma osmolality and body fluid volume

1986 ◽  
Vol 156 (3) ◽  
pp. 377-381 ◽  
Author(s):  
R. Keith Dupr� ◽  
Eugene C. Crawford
Keyword(s):  
Body Fluid ◽  
Plasma Osmolality ◽  
Fluid Volume ◽  
Dipsosaurus Dorsalis ◽  
Body Fluid Volume ◽  
Panting Threshold

scholarly journals The contribution of plasma urea to total osmolality during iatrogenic fluid reduction in critically ill patients

Function ◽  
2021 ◽  
Author(s):  
Sandra Nihlén ◽  
Robert Frithiof ◽  
Jens Titze ◽  
Rafael Kawati ◽  
Johan Rasmusson ◽  
...  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Body Fluid ◽  
Plasma Osmolality ◽  
Body Water ◽  
Fluid Volume ◽  
Volume Reduction ◽  
Icu Patients ◽  
Nitrogen Intake ◽  
Body Fluid Volume

Abstract Hyperosmolality is common in critically ill patients during body fluid volume reduction. It is unknown whether this is only a result of decreased total body water, or an active osmole-producing mechanism similar to that in aestivating animals where muscle degradation increases urea levels to preserve water. We hypothesized that fluid volume reduction in critically ill patients contributes to a shift from ionic to organic osmolytes similar to mechanisms of aestivation. We performed a post-hoc analysis on data from a multicenter observational study in adult ICU patients in the post-resuscitative phase. Fluid, electrolyte, energy and nitrogen intake, fluid loss, estimated glomerular filtration rate (eGFR) and estimated plasma osmolality (eOSM) were registered. Contributions of osmolytes Na+, K+, urea and glucose to eOSM expressed as proportions of eOSM were calculated. 241 patients were included. eOSM increased (median change 7.4 mOsm/kg (IQR −1.9–18) during the study. The of sodium's and potassium's proportions of eOSM decreased (P < 0.05 and P < 0.01 respectively), whereas the urea's proportion increased (P < 0.001). Urea's proportion of eOSM was higher in patients with negative vs. positive fluid balance. The urea's proportion of eOSM increased with eOSM (r = 0.63; adjusted for eGFR r = 0.80), but not nitrogen intake. In patients without furosemide and/or renal replacement therapy (n = 17), urea's proportion of eOSM and eOSM correlated strongly (r = 0.92). Urea's proportion of eOsm was higher in patients not surviving to 90 days. In stabilized ICU patients the contribution of urea to plasma osmolality increased during body water volume reduction, statistically independently of nitrogen administration and eGFR. The shift from ionic osmolytes to urea during body fluid volume reduction is similar to that seen in aestivating animals. ClinicalTrials.org Identifier: NCT03972475

Effects of hyperosmolality and diuretics on heat-induced limb vasodilation in baboons

1990 ◽  
Vol 258 (2) ◽  
pp. R309-R317 ◽  
Author(s):  
D. W. Proppe
Keyword(s):  
Blood Flow ◽  
Body Fluid ◽  
Extracellular Fluid ◽  
Plasma Osmolality ◽  
External Iliac Artery ◽  
Sodium Concentration ◽  
Fluid Volume ◽  
Extracellular Fluid Volume ◽  
Acute Elevation ◽  
Body Fluid Volume

Dehydration attenuates the increase in limb skin blood flow elicited by environmental heating (EH). This study sought to determine which of the two primary effects of dehydration, increased body fluid osmolality or decreased body fluid volume, was primarily responsible for this cutaneous vasoconstrictor bias in baboons. Unanesthetized chronically instrumented baboons were exposed to EH while in euhydrated state, after 65-69 h of water deprivation (dehydration), after infusion of a small volume of hypertonic (20%) saline to raise plasma osmolality and sodium concentration to dehydration levels, and after injections of the diuretic furosemide over a 64-h period to produce an isosmotic fall in extracellular fluid volume. EH consisted of an acute elevation of ambient temperature to 39.5-42.0 degrees C until internal temperature reached 39.5-39.8 degrees C. The normal increases in external iliac artery blood flow and iliac vascular conductance during EH were unchanged by hyperosmolality but were attenuated by 39 and 31%, respectively, after furosemide treatment and by 42 and 46%, respectively, during dehydration. Thus the fall in extracellular fluid volume is the component of dehydration that attenuates the increase in hindlimb blood flow during EH in the same way as dehydration itself.

scholarly journals A Possible Physiological Role of Atrial Natriuretic Peptide in Body Fluid Volume Regulation

1988 ◽  
Vol 13 ◽  
pp. S62-S68
Author(s):  
Yasunobu Hirata ◽  
Masao Ishii ◽  
Kazushige Fukui ◽  
Hiroshi Hayakawa ◽  
Shin-ichiro Namba ◽  
...  
Keyword(s):  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Volume Regulation ◽  
Body Fluid ◽  
Physiological Role ◽  
Fluid Volume ◽  
Body Fluid Volume ◽  
Fluid Volume Regulation ◽  
Atrial Natriuretic

scholarly journals Apparent paradox of neurohumoral axis inhibition after body fluid volume depletion in patients with chronic congestive heart failure and water retention.

Heart ◽  
1994 ◽  
Vol 72 (6) ◽  
pp. 534-539 ◽  
Author(s):  
M D Guazzi ◽  
P Agostoni ◽  
B Perego ◽  
G Lauri ◽  
A Salvioni ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Body Fluid ◽  
Water Retention ◽  
Fluid Volume ◽  
Chronic Congestive Heart Failure ◽  
Volume Depletion ◽  
Apparent Paradox ◽  
Body Fluid Volume

scholarly journals Dehydration increases the density of C receptors for ANF on rat glomerular membranes

1990 ◽  
Vol 258 (4) ◽  
pp. R1084-R1088 ◽  
Author(s):  
M. C. Kollenda ◽  
A. M. Vollmar ◽  
G. A. McEnroe ◽  
A. L. Gerbes
Keyword(s):  
Binding Sites ◽  
Atrial Natriuretic Factor ◽  
Body Fluid ◽  
Fluid Volume ◽  
Control Group ◽  
Receptor Density ◽  
Lower Plasma ◽  
Short Term ◽  
Salt Loading ◽  
Body Fluid Volume

The present study determined the presence of two types of binding sites for atrial natriuretic factor (ANF), the B and C receptor, on rat glomerular membranes. The effect of short-term salt loading and dehydration on these two receptor populations was investigated consecutively. Salt-loaded rats did not show significant changes in plasma ANF concentrations or in the number of ANF binding sites. Water-deprived rats presented significantly lower plasma ANF concentrations (22.0 +/- 1.9 vs. 34.4 +/- 3.8 fmol/ml, P less than 0.01) and an increase in total receptor density (1,860 +/- 398 vs. 987 +/- 143 fmol/mg protein) as compared with the control group. Differentiation of both receptor populations showed that it was the C receptors that accounted for this increase (1,772 +/- 369 vs. 901 +/- 151 fmol/mg protein, P less than 0.05), whereas B-receptor density was unchanged (89 +/- 31 vs. 87 +/- 44 fmol/mg protein). These data suggest that C receptors for ANF are affected by changes of body fluid volume.

scholarly journals On the question of body fluid volume or sodium status influencing renin release.

1977 ◽  
Vol 267 (2) ◽  
pp. 321-338 ◽  
Author(s):  
J R Blair-West ◽  
A H Brook ◽  
P A Simpson
Keyword(s):  
Body Fluid ◽  
Fluid Volume ◽  
Renin Release ◽  
Body Fluid Volume

Role of Leptin in the Regulation of Body Fluid Volume and Pressures

2003 ◽  
Vol 10 (3) ◽  
pp. 211-218 ◽  
Author(s):  
Prabal K. Guha ◽  
Daniel Villarreal ◽  
Garry P. Reams ◽  
Ronald H. Freeman
Keyword(s):  
Body Fluid ◽  
Fluid Volume ◽  
Body Fluid Volume

Angiotensin II and III upregulate body fluid volume of the clam worm Perinereis sp. via angiotensin II receptors in different manners

Peptides ◽  
2005 ◽  
Vol 26 (12) ◽  
pp. 2452-2457 ◽  
Author(s):  
Ryousuke Satou ◽  
Tsutomu Nakagawa ◽  
Hiroki Ido ◽  
Masayuki Tomomatsu ◽  
Fumiaki Suzuki ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Body Fluid ◽  
Fluid Volume ◽  
Angiotensin Ii Receptors ◽  
Body Fluid Volume

scholarly journals 948-52 Paradoxical Neurohumoral Axis Inhibition After Body Fluid Volume Depletion in Patients with Congestive Heart Failure and Water Retention

1995 ◽  
Vol 25 (2) ◽  
pp. 178A ◽  
Author(s):  
Maurizio D. Guazzi ◽  
Piergiuseppe Agostoni ◽  
G. Battista Perego ◽  
Gianfranco Lauri ◽  
Francesco Giraldi ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Body Fluid ◽  
Water Retention ◽  
Fluid Volume ◽  
Volume Depletion ◽  
Body Fluid Volume

Control of body fluid volume regarded as a feedback system

1966 ◽  
Vol 4 (6) ◽  
pp. 567-574 ◽  
Author(s):  
M. Nagasaka ◽  
K. Shimizu ◽  
T. Maeda ◽  
Y. Yoshitoshi ◽  
S. Koshikawa ◽  
...  
Keyword(s):  
Body Fluid ◽  
Feedback System ◽  
Fluid Volume ◽  
Body Fluid Volume
Sign in / Sign up

Export Citation Format

Share Document