Two-site assay of human α1-fetoprotein using125I-labelled monoclonal antibodies
Keyword(s):
Monoclonal antibodies to human α1-ietoprotein (AFP) have been compared with a conventionally produced antiserum using radioimmunoassay and two-site immunoradiometric techniques. A low-affinity antibody, which proved inadequate for use in a radioimmunoassay, gave asatisfactory dose-response Curve in a rapid two-site assay. A higher-affinity antibody yielded a simple, rapid, and sensitive two-site assay suitable for routine measurement of serum AFP.
1997 ◽
Vol 4
(4)
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pp. 197-202
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1981 ◽
Vol 27
(11)
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pp. 1838-1844
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2018 ◽
Vol 22
(1)
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pp. 1.e1-1.e6
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