Amino acid composition of human liver mitochondrial membranes in normal and pathological conditions

1991 ◽  
Vol 11 (2) ◽  
pp. 95-100 ◽  
Author(s):  
Gheorghe Benga ◽  
Adriana Hodârnău ◽  
Rozalia Tilinca ◽  
Victoria Borza ◽  
William Ferdinand
Keyword(s):  
Liver Cirrhosis ◽  
Amino Acid ◽  
Obstructive Jaundice ◽  
Fatty Liver ◽  
Amino Acid Composition ◽  
Acid Composition ◽  
Normal Liver ◽  
Mitochondrial Membranes ◽  
Pathological Conditions ◽  
Methionine Content

The amino acid composition of proteins from liver mitochondrial membranes has been studied in patients with normal liver, with biliary diseases and fatty liver, with obstructive jaundice or liver cirrhosis. A characteristic pattern of the amino acid composition in patients with normal liver has been found. In the mitochondrial membranes of patients with fatty liver tryptophan and lysine were decreased while [aspartic acid plus asparagine] and [glutamic acid plus glutamine] were increased compared to their counterpart in the normal liver. In patients with obstructive jaundice of short duration (less than two months) only a slight decrease in methionine content was found, while in the case of liver cirrhosis amino acid composition was markedly changed.

Amino acid composition of rat and human liver microsomes in normal and pathological conditions

1995 ◽  
Vol 15 (2) ◽  
pp. 111-116 ◽  
Author(s):  
Gheorghe Benga ◽  
William Ferdinand
Keyword(s):  
Liver Cirrhosis ◽  
Amino Acid ◽  
Obstructive Jaundice ◽  
Amino Acid Composition ◽  
Acid Composition ◽  
Human Subjects ◽  
Liver Microsomes ◽  
Normal Liver ◽  
Pathological Conditions ◽  
Species Specific

The amino acid composition of proteins from liver microsomes has been studied in rats and in human subjects with normal liver, with obstructive jaundice or liver cirrhosis. The pattern of the amino acid composition of microsomes appeared to be species-specific. Phenylalanine, threonine, serine, proline, histidine and [aspartic acid plus asparagine] were increased, while alanine, tyrosine, glycine and arginine were decreased in the human compared to the rat microsomes. In patients with obstructive jaundice of short duration (less than two months) only a slight decrease in leucine and phenylalanine could be noticed, while in the case of liver cirrhosis amino acid composition was markedly changed.

scholarly journals Interrelation between plasma amino acid composition and growth hormone secretion in patients with liver cirrhosis.

1984 ◽  
Vol 31 (5) ◽  
pp. 557-564 ◽  
Author(s):  
SHOJIRO NAOMI ◽  
TERUHISA UMEDA ◽  
JUNICHI TAJIRI ◽  
JUNNOSUKE INOUE ◽  
SHINICHIRO HAMASAKI ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Liver Cirrhosis ◽  
Amino Acid ◽  
Amino Acid Composition ◽  
Acid Composition ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Plasma Amino Acid

Effect of maternal diet on the amino acid composition of human uterine fluid

2014 ◽  
Author(s):  
Alexandra Jayne Kermack ◽  
Ying Cheong ◽  
Nick Brook ◽  
Nick Macklon ◽  
Franchesca D Houghton
Keyword(s):  
Amino Acid ◽  
Amino Acid Composition ◽  
Acid Composition ◽  
Maternal Diet ◽  
Uterine Fluid
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