scholarly journals Interrelation between plasma amino acid composition and growth hormone secretion in patients with liver cirrhosis.

1984 ◽  
Vol 31 (5) ◽  
pp. 557-564 ◽  
Author(s):  
SHOJIRO NAOMI ◽  
TERUHISA UMEDA ◽  
JUNICHI TAJIRI ◽  
JUNNOSUKE INOUE ◽  
SHINICHIRO HAMASAKI ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Liver Cirrhosis ◽  
Amino Acid ◽  
Amino Acid Composition ◽  
Acid Composition ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Plasma Amino Acid

Effects of plasma amino acid and hormone levels on renal hemodynamics in humans

1988 ◽  
Vol 255 (3) ◽  
pp. F444-F449 ◽  
Author(s):  
P. Castellino ◽  
C. Giordano ◽  
A. Perna ◽  
R. A. DeFronzo
Keyword(s):  
Growth Hormone ◽  
Amino Acid ◽  
Acid Solution ◽  
Growth Hormone Secretion ◽  
Renal Hemodynamics ◽  
Time Sequence ◽  
Plasma Amino Acid ◽  
Base Line ◽  
Amino Acid Solution ◽  
Hormone Levels

The effect of plasma amino acid and hormone (insulin, glucagon, and growth hormone) levels on renal hemodynamics was studied in 18 healthy subjects. The following four protocols were employed: study 1, a balanced amino acid solution was infused for 3 h to increase plasma amino acid concentrations two to three times base line; study 2, the same amino acid solution was infused with somatostatin (SRIF) and infusions of insulin, glucagon, and growth hormone were concomitantly administered to replace the time sequence of increase in peripheral concentrations of these hormones as observed during study 1; study 3, the same amino acid infusion was administered with SRIF plus infusions of insulin, glucagon, and growth hormone to maintain plasma hormone concentrations constant at the basal level; study 4, SRIF was infused with insulin, glucagon, and growth hormone to reproduce the time sequence of increase of these hormones as observed in study 1; amino acids were not infused in this study. During study 1, glomerular filtration rate (GFR) and renal plasma flow (RPF) rose by 19 and 21%, respectively. During study 2 both the time sequence of and magnitude of rise in GFR and in RPF were similar to the changes observed during study 1. In studies 3 and 4 neither RPF nor GFR changed significantly from base line. These results indicate that 1) hyperaminoacidemia stimulates insulin/glucagon/growth hormone secretion and causes a modest rise in GFR and RPF; and 2) if hyperaminoacidemia is created while maintaining basal hormone levels constant or if plasma insulin/glucagon/growth hormone levels are increased while maintaining the plasma amino acid concentration at basal levels, neither RPF nor GFR rise.(ABSTRACT TRUNCATED AT 250 WORDS)

scholarly journals Molecular characterization of the bovine <i>GHRL</i> gene (Short Communication)

2009 ◽  
Vol 52 (1) ◽  
pp. 79-84 ◽  
Author(s):  
F. G. Colinet ◽  
D. Portetelle ◽  
R. Renaville
Keyword(s):  
Growth Hormone ◽  
Amino Acid ◽  
Short Communication ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Endogenous Ligand ◽  
Growth Hormone Secretagogue Receptor ◽  
Growth Hormone Secretagogue ◽  
Amino Acid Peptide

Abstract. Bovine ghrelin, a 27 amino acid peptide, has been identified in oxyntic glands of the abomasum. It is an endogenous ligand for growth hormone secretagogue receptor and stimulates food intake and growth hormone secretion. The bovine GHRL gene was completely sequenced and consists of five exons and four introns. Like mouse and human GHRL genes, we found that the bovine GHRL gene also contains a first non-coding exon of 21 bp. The bovine GHRL gene codes for 116 amino acid peptide named preproghrelin which contains the ghrelin peptide and another peptide similar to obestatin. Sequence analysis revealed eight polymorphisms, which are located in the non-coding sequence of the gene.

scholarly journals Antagonism by Taurine of Morphine Induced Growth Hormone Secretion

1978 ◽  
Vol 5 (1) ◽  
pp. 139-142 ◽  
Author(s):  
R. Collu ◽  
G. Charpenet ◽  
M. J. Clermont
Keyword(s):  
Growth Hormone ◽  
Amino Acid ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Physiological Role ◽  
Pituitary Hormone ◽  
Hormone Release ◽  
Morphine Administration ◽  
Plasma Gh

SUMMARY:The intraperitoneal (IP) or intraventricular (IVT) administration of small amounts of taurine did not modify pentobarbital-induced sleep or pituitary hormone release. However, the drastic increment in plasma GH values induced by morphine administration was completely blocked by the IVT injection of the amino acid. Whether taurine plays a physiological role in the control ofGH secretion is highly speculative.

scholarly journals Modification of fetal plasma amino acid composition by placental amino acid exchangersin vitro

2007 ◽  
Vol 582 (2) ◽  
pp. 871-882 ◽  
Author(s):  
Jane K. Cleal ◽  
Paul Brownbill ◽  
Keith M. Godfrey ◽  
John M. Jackson ◽  
Alan A. Jackson ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Composition ◽  
Acid Composition ◽  
Plasma Amino Acid ◽  
Fetal Plasma

Amino acid composition of rat and human liver microsomes in normal and pathological conditions

1995 ◽  
Vol 15 (2) ◽  
pp. 111-116 ◽  
Author(s):  
Gheorghe Benga ◽  
William Ferdinand
Keyword(s):  
Liver Cirrhosis ◽  
Amino Acid ◽  
Obstructive Jaundice ◽  
Amino Acid Composition ◽  
Acid Composition ◽  
Human Subjects ◽  
Liver Microsomes ◽  
Normal Liver ◽  
Pathological Conditions ◽  
Species Specific

The amino acid composition of proteins from liver microsomes has been studied in rats and in human subjects with normal liver, with obstructive jaundice or liver cirrhosis. The pattern of the amino acid composition of microsomes appeared to be species-specific. Phenylalanine, threonine, serine, proline, histidine and [aspartic acid plus asparagine] were increased, while alanine, tyrosine, glycine and arginine were decreased in the human compared to the rat microsomes. In patients with obstructive jaundice of short duration (less than two months) only a slight decrease in leucine and phenylalanine could be noticed, while in the case of liver cirrhosis amino acid composition was markedly changed.

The effect of “Remivital” on plasma amino acid composition in dairy cows with ketosis

2016 ◽  
Vol 3 (1) ◽  
pp. 73-79
Author(s):  
M. Simonov ◽  
V. Vlizlo
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Dairy Cows ◽  
Amino Acid Composition ◽  
Propylene Glycol ◽  
Acid Composition ◽  
Intravenous Injection ◽  
Contractile Proteins ◽  
Plasma Amino Acid ◽  
High Yield

Aim. To investigate plasma amino acid composition in dairy cows after ketosis conventional (oral administra- tion of propylene glycol, intravenous injection of glucose and insulin) and proposed treatment (oral administra- tion of propylene glycol, intravenous injection of “Remivital”). Methods. Study was performed on high yield- ing dairy cows with clinical ketosis during their 2 nd to 4 th lactation with milk yield above 8000 L per previous lactation. Content of free amino acids was determined in plasma before and after treatment using amino acid analyzer. Results. Lowering of the level of ketogenic amino acids was revealed after conducted treatment as well as increase in the level of glycogenic and branched amino acids. Signifi cant lowering of the level of meth- ylhistidine gives evidence of decreased catabolism of contractile proteins. Conclusions. Proposed treatment regimen has proven to be superior, since signifi cantly higher level of ornithine and lower level of citrulline were revealed after administration of conventional regimen, which gives evidence of problems in disposal of ammonia and lactate. Moreover, in case of administration of traditional scheme, the concentration of markers of catabolism of contractile proteins was still high, in contrast with such in animals, which were administered proposed regimen, and high concentration of isoleucine contributes to aggravation of ketoacidosis.

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