scholarly journals Lactate dehydrogenase activity and isoenzyme patterns in skeletal muscle, fat, exocrine pancreas and isolated pancreatic islets of normal and obese-hyperglycaemic mice

Diabetologia ◽  
1970 ◽  
Vol 6 (5) ◽  
pp. 493-498 ◽  
Author(s):  
B. Prochazka ◽  
M. A. Qureshi ◽  
A. J. Matty
1984 ◽  
Vol 30 (10) ◽  
pp. 1708-1709
Author(s):  
D L Smalley ◽  
B Womack ◽  
C Handorf ◽  
S Acchiardo

Abstract A 65-year-old woman failed to develop increased creatine kinase or lactate dehydrogenase activity after a myocardial infarction. She had no measurable creatine kinase MB isoenzyme and no detectable patterns of normal LD isoenzyme activity. These determinations five months after the infarction showed normal values for total activity and isoenzyme patterns.


1991 ◽  
Vol 71 (6) ◽  
pp. 2114-2121 ◽  
Author(s):  
A. X. Bigard ◽  
A. Brunet ◽  
C. Y. Guezennec ◽  
H. Monod

The effects of endurance training on the skeletal muscle of rats have been studied at sea level and simulated high altitude (4,000 m). Male Wistar rats were randomly assigned to one of four groups: exercise at sea level, exercise at simulated high altitude, sedentary at sea level, and sedentary at high altitude (n = 8 in each group). Training consisted of swimming for 1 h/day in water at 36 degrees C for 14 wk. Training and exposure to a high-altitude environment produced a decrease in body weight (P less than 0.001). There was a significant linear correlation between muscle mass and body weight in the animals of all groups (r = 0.89, P less than 0.001). High-altitude training enhanced the percentage of type IIa fibers in the extensor digitorum longus muscle (EDL, P less than 0.05) and deep portions of the plantaris muscle (dPLA, P less than 0.01). High-altitude training also increased the percentage of type IIab fibers in fast-twitch muscles. These muscles showed marked metabolic adaptations: training increased the activity levels of enzymes involved in the citric acid cycle (citrate synthase, CS) and the beta-oxidation of fatty acids (3 hydroxyacyl CoA dehydrogenase, HAD). This increase occurred mainly at high altitude (36 and 31% for HAD in EDL and PLA muscles; 24 and 31% for CS in EDL and PLA muscles). Training increased the activity of enzymes involved in glucose phosphorylation (hexokinase). High-altitude training decreased lactate dehydrogenase activity. Endurance training performed at high altitude and sea level increased the isozyme 1-to-total lactate dehydrogenase activity ratio to the same extent.(ABSTRACT TRUNCATED AT 250 WORDS)


2004 ◽  
Vol 95 (1) ◽  
pp. 38-42 ◽  
Author(s):  
Jaroslaw Dudka ◽  
Franciszek Burdan ◽  
Agnieszka Korobowicz ◽  
Robert Klepacz ◽  
Elzbieta Korobowicz

2019 ◽  
Vol 11 (10) ◽  
pp. 4349-4356
Author(s):  
Seong Cheol Jeong ◽  
Jae Jun Kim ◽  
Yong Hwan Kim ◽  
In Sub Kim ◽  
Jung Wook Han

Author(s):  
Jadwiga Gronczewska ◽  
Anna Biegniewska ◽  
Marek S. Ziętara ◽  
Edward F. Skorkowski

1987 ◽  
Vol 6 (4) ◽  
pp. 555-560 ◽  
Author(s):  
David Sempol ◽  
Edurado Osinaga ◽  
Seymour Zigman ◽  
Israel Korc ◽  
Beatriz Korc ◽  
...  

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