Isolation and characterization of a Chinese hamster lung cell tryptophanyl-tRNA synthetase mutant

1984 ◽  
Vol 10 (2) ◽  
pp. 161-170
Author(s):  
Stephen M. W. Chang ◽  
John J. Wasmuth
Keyword(s):  
Chinese Hamster ◽  
Trna Synthetase ◽  
Isolation And Characterization

scholarly journals Biochemical characterization of a mutant asparaginyl-tRNA synthetase from Chinese hamster ovary cells.

1978 ◽  
Vol 253 (1) ◽  
pp. 58-62 ◽  
Author(s):  
I.L. Andrulis ◽  
C.S. Chiang ◽  
S.M. Arfin ◽  
T.A. Miner ◽  
G.W. Hatfield
Keyword(s):  
Chinese Hamster Ovary ◽  
Biochemical Characterization ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Trna Synthetase ◽  
Ovary Cells

scholarly journals Isolation and characterization of bleomycin-resistant clones of CHO cells

1979 ◽  
Vol 34 (3) ◽  
pp. 269-279 ◽  
Author(s):  
Sylvia Brabbs ◽  
J. R. Warr
Keyword(s):  
Enzyme Activity ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Tween 80 ◽  
The Other ◽  
Resistant Clone ◽  
Ovary Cells ◽  
Isolation And Characterization ◽  
Significant Difference

SUMMARYFive clones of Chinese hamster ovary cells with increased resistance to bleomycin have been isolated following ethylmethanesulphonate mutagenesis. Resistance was stable in three of the clones, but unstable in the other two. One of the stably resistant clones was cross resistant to unrelated drugs, and in contrast to the parental cells, its response to bleomycin was potentiated by tween 80. These two observations suggested a membrane alteration in the resistant clone. There was no significant difference in bleomycin-inactivating enzyme activity between the parental and resistant clones.

Isolation and characterization of Chinese hamster ovary cell mutants with altered sensitivity to high doses of tunicamycin

1981 ◽  
Vol 7 (5) ◽  
pp. 507-521 ◽  
Author(s):  
Michihiko Kuwano ◽  
Toshiko Tabuki ◽  
Shin-ichi Akiyama ◽  
Kumato Mifune ◽  
Akira Takatsuki ◽  
...  
Keyword(s):  
Chinese Hamster Ovary Cell ◽  
Chinese Hamster Ovary ◽  
Chinese Hamster ◽  
Ovary Cell ◽  
Isolation And Characterization ◽  
High Doses ◽  
Altered Sensitivity
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