Cloning and sequence comparison ofAvaI andBsoBI restriction-modification systems

1996 ◽  
Vol 252 (6) ◽  
pp. 695-699 ◽  
Author(s):  
H. Ruan ◽  
K. D. Lunnen ◽  
M. E. Scott ◽  
L. S. Moran ◽  
B. E. Slatko ◽  
...  
Keyword(s):  
Sequence Comparison ◽  
Restriction Modification ◽  
Restriction Modification Systems

Sequence Comparison of the EcoHK31I and EaeI. Restriction-Modification Systems Suggests an Intergenic Transfer of Genetic Material

1998 ◽  
Vol 379 (4-5) ◽  
pp. 437-442 ◽  
Author(s):  
Kai-Fai Lee ◽  
Pang-Chui Shaw ◽  
Steven J. Picone ◽  
Geoffrey G. Wilson ◽  
Keith D. Lunnen
Keyword(s):  
Sequence Comparison ◽  
Genetic Material ◽  
Restriction Modification ◽  
Restriction Modification Systems

Methylases of the Type II Restriction-Modification Systems

1984 ◽  
pp. 39-71 ◽  
Author(s):  
Hamilton O. Smith ◽  
Samuel V. Kelly
Keyword(s):  
Type Ii ◽  
Restriction Modification ◽  
Restriction Modification Systems

Restriction-Modification Systems

2019 ◽  
Author(s):  
Kommireddy Vasu ◽  
Desirazu N. Rao ◽  
Valakunja Nagaraja
Keyword(s):  
Restriction Modification ◽  
Restriction Modification Systems

Two different restriction-modification systems for degrading exogenous DNA in Paenibacillus polymyxa

2018 ◽  
Vol 504 (4) ◽  
pp. 927-932 ◽  
Author(s):  
Minjia Shen ◽  
Ziyan Chen ◽  
Xudan Mao ◽  
Lin Wang ◽  
Jingyi Liang ◽  
...  
Keyword(s):  
Paenibacillus Polymyxa ◽  
Exogenous Dna ◽  
Restriction Modification ◽  
Restriction Modification Systems

scholarly journals Avoidance of recognition sites of restriction-modification systems is a widespread but not universal anti-restriction strategy of prokaryotic viruses

BMC Genomics ◽  
2018 ◽  
Vol 19 (1) ◽  
Author(s):  
I. S. Rusinov ◽  
A. S. Ershova ◽  
A. S. Karyagina ◽  
S. A. Spirin ◽  
A. V. Alexeevski
Keyword(s):  
Recognition Sites ◽  
Restriction Strategy ◽  
Restriction Modification ◽  
Restriction Modification Systems

scholarly journals DNA sequence repeats identify numerous Type I restriction‐modification systems that are potential epigenetic regulators controlling phase‐variable regulons; phasevarions

2019 ◽  
Vol 34 (1) ◽  
pp. 1038-1051 ◽  
Author(s):  
John M. Atack ◽  
Chengying Guo ◽  
Long Yang ◽  
Yaoqi Zhou ◽  
Michael P. Jennings
Keyword(s):  
Dna Sequence ◽  
Type I ◽  
Phase Variable ◽  
Numerous Type ◽  
Epigenetic Regulators ◽  
Dna Sequence Repeats ◽  
Restriction Modification ◽  
Restriction Modification Systems

scholarly journals Genetic variation regulates the activation and specificity of Restriction-Modification systems in Neisseria gonorrhoeae

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Leonor Sánchez-Busó ◽  
Daniel Golparian ◽  
Julian Parkhill ◽  
Magnus Unemo ◽  
Simon R. Harris
Keyword(s):  
Neisseria Gonorrhoeae ◽  
Single Molecule ◽  
Regulation Of Gene Expression ◽  
Phase Variation ◽  
Type I ◽  
Dam Methylase ◽  
Different Strains ◽  
Methylation Patterns ◽  
Restriction Modification ◽  
Restriction Modification Systems

Abstract Restriction-Modification systems (RMS) are one of the main mechanisms of defence against foreign DNA invasion and can have an important role in the regulation of gene expression. The obligate human pathogen Neisseria gonorrhoeae carries one of the highest loads of RMS in its genome; between 13 to 15 of the three main types. Previous work has described their organization in the reference genome FA1090 and has inferred the associated methylated motifs. Here, we studied the structure of RMS and target methylated motifs in 25 gonococcal strains sequenced with Single Molecule Real-Time (SMRT) technology, which provides data on DNA modification. The results showed a variable picture of active RMS in different strains, with phase variation switching the activity of Type III RMS, and both the activity and specificity of a Type I RMS. Interestingly, the Dam methylase was found in place of the NgoAXI endonuclease in two of the strains, despite being previously thought to be absent in the gonococcus. We also identified the real methylation target of NgoAXII as 5′-GCAGA-3′, different from that previously described. Results from this work give further insights into the diversity and dynamics of RMS and methylation patterns in N. gonorrhoeae.

scholarly journals Phase-variable restriction/modification systems are required for Helicobacter pylori colonization

Gut Pathogens ◽  
2014 ◽  
Vol 6 (1) ◽  
Author(s):  
Jonathan C Gauntlett ◽  
Hans-Olof Nilsson ◽  
Alma Fulurija ◽  
Barry J Marshall ◽  
Mohammed Benghezal
Keyword(s):  
Helicobacter Pylori ◽  
Phase Variable ◽  
Restriction Modification ◽  
Restriction Modification Systems
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