Specific serum antibodies against membranous proteins of a human immortal chondrocytic cell line (HCS-2/8) in rheumatoid arthritis and their relationship to the natural history of this disease

1996 ◽  
Vol 14 (3) ◽  
pp. 146-152 ◽  
Author(s):  
Akira Sakawa ◽  
Yasutaka Yutani ◽  
Kentaro Inui ◽  
Akira Shimazu ◽  
Yoshiki Yamano ◽  
...  
1997 ◽  
Vol 10 (4) ◽  
pp. 275???281 ◽  
Author(s):  
Keiju Fujiwara ◽  
Kazuo Yonenobu ◽  
Takahiro Ochi

Blood ◽  
1977 ◽  
Vol 49 (3) ◽  
pp. 367-370 ◽  
Author(s):  
DW Golde ◽  
C Burgaleta ◽  
RS Sparkes ◽  
MJ Cline

Three patients with chronic myelocytic leukemia in different phases of the natural history of the disease were studied. Their bone marrow cells were cultured under conditions favoring macrophage proliferation, and parallel cytogenetic and cytochemical studies were performed. All cell metaphases examined contained the Ph1 chromosome at a time when more than 80% of these metaphases were in identifiable macrophages. We conclude that the mononuclear phagocyte cell line contains the abnormal chromosome in Ph1-positive chronic myelocytic leukemia.


2013 ◽  
Vol 7 (1) ◽  
pp. 22-28
Author(s):  
Arianna Giannetti ◽  
Giampaolo Ricci ◽  
Arianna Dondi ◽  
Valentina Piccinno ◽  
Federica Bellini ◽  
...  

Background: The natural history and the prognostic factors for food tolerance in childhood atopic dermatitis(AD) are poorly understood. Objective: We aimed at investigating the natural course of egg and milk allergy in children affected by AD and food allergy and identifying if the persistence of allergy is associated with high specific serum IgE(sIgE). Methods: The retrospective study included 58 patients affected by AD, aged 9-16 months, with a first clinical examination between 1993 and 2002. Results: Patients with AD and allergy to hen’s egg(N=58) or cow’s milk(N=44) were studied. In most patients milk and egg tolerance was reached before school age, but it was achieved later in children with severe AD and high egg sIgE. Conclusions: The food tolerance is normally reached before school age and, at the time of diagnosis, levels of sIgE>5kU/L for hen’s egg are risk factors for a later tolerance achievement.


2019 ◽  
Vol 41 (7) ◽  
pp. 1256-1269 ◽  
Author(s):  
Kevin D. Deane ◽  
V. Michael Holers

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