Purification and properties of carnitine acetyltransferase from citric acid producingAspergillus niger

1996 ◽  
Vol 60 (2) ◽  
pp. 151-158 ◽  
Author(s):  
K. Jernejc ◽  
M. Legiša
1983 ◽  
Vol 93 (2) ◽  
pp. 439-451 ◽  
Author(s):  
Shoko MIYAZAWA ◽  
Hisashi OZASA ◽  
Shuichi FURUTA ◽  
Takashi OSUMI ◽  
Takashi HASHIMOTO

1990 ◽  
Vol 189 (3) ◽  
pp. 539-546 ◽  
Author(s):  
Wilma BLOISI ◽  
Irma COLOMBO ◽  
Barbara GARAVAGLIA ◽  
Roberto GIARDINI ◽  
Gaetano FINOCCHIARO ◽  
...  

1991 ◽  
Vol 81 (3) ◽  
pp. 327-334 ◽  
Author(s):  
Cesar V. Mujer ◽  
Dale W. Kretchman ◽  
A. Raymond Miller

1995 ◽  
Vol 94 (4) ◽  
pp. 629-634 ◽  
Author(s):  
Mohamed Benichou ◽  
Gracia Martinez-Reina ◽  
Felix Romojaro ◽  
Jean-Claude Pech ◽  
Alain Latche

2020 ◽  
Vol 140 ◽  
pp. 25-29
Author(s):  
K Akiyama ◽  
N Hirazawa ◽  
A Hatanaka

Oxytetracycline (OTC) has been commonly used as an effective antibiotic against various fish bacterial diseases, including vibriosis. In this study, the absorption-enhancing effect of citric acid on oral OTC pharmacokinetics and treatment of artificial Vibrio anguillarum infection was evaluated in juvenile yellowtail Seriola quinqueradiata followed by serum OTC concentration analysis. When 25 mg kg-1 body weight (BW) OTC was administered in combination with 1250 mg kg-1 BW citric acid, the serum OTC concentration reached almost the same concentration as that of the group treated with 50 mg kg-1 BW OTC. This coadministration successfully suppressed mortality due to vibriosis similar to the group treated with 50 mg kg-1 BW OTC. Conversely, poor efficacy was observed when only 25 mg kg-1 BW OTC was administered. These results suggest that coadministration of citric acid can be beneficial in reducing the dose of OTC needed for effective treatment, and thus contributes to the goal of reduced use of this antibiotic in aquaculture.


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