Diagnostic value of enhanced computed tomography in the detection of the widely spreading intraductal component of breast cancer: Case reports

Introduction: Carcinomatous meningitis in breast cancer occurs as a complication in up to 5% of all cases. It is a very devastating diagnosis, with a median patient survival of about 3 months. Treatment is very controversial, and different modalities of treatment have been used but none of them show significant benefit for overall survival. Case Reports: We report 2 cases of carcinomatous meningitis in breast cancer patients. They received a similar treatment of a combination of intrathecal (IT) methotrexate followed by craniospinal radiotherapy. Both patients survived for many years after treatment and are in complete clinical and radiological remission. Conclusion: Meningeal metastasis from breast cancer can be very effectively treated with IT and/or systemic chemotherapy followed by craniospinal radiotherapy. Further studies are needed to determine the effectiveness of this sequential combination of chemotherapy with radiotherapy.

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Changes in Findings of Mammography, Ultrasonography and Contrast-enhanced Computed Tomography of Three Histological Complete Responders with Primary Breast Cancer Before and After Neoadjuvant Chemotherapy: Case Reports

Japanese Journal of Clinical Oncology ◽

10.1093/jjco/hyd119 ◽

2000 ◽

Vol 30 (10) ◽

pp. 453-457 ◽

Cited By ~ 9

Author(s):

T. Nakamura

Keyword(s):

Breast Cancer ◽

Computed Tomography ◽

Neoadjuvant Chemotherapy ◽

Primary Breast Cancer ◽

Case Reports ◽

Contrast Enhanced ◽

Before And After ◽

Enhanced Computed Tomography ◽

Contrast Enhanced Computed Tomography

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Interdisciplinary Management of Transgender Individuals at Risk for Breast Cancer: Case Reports and Review of the Literature

Clinical Breast Cancer ◽

10.1016/j.clbc.2018.11.007 ◽

2019 ◽

Vol 19 (1) ◽

pp. e12-e19 ◽

Cited By ~ 12

Author(s):

Julia Eismann ◽

Yujing J. Heng ◽

Kristin Fleischmann-Rose ◽

Adam M. Tobias ◽

Jordana Phillips ◽

...

Keyword(s):

Breast Cancer ◽

At Risk ◽

Case Reports ◽

Breast Cancer Case ◽

Cancer Case ◽

Interdisciplinary Management ◽

Review Of The Literature

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Contrast-enhanced computed tomography for diagnosing the intraductal component and small invasive foci of Breast Cancer

Breast Cancer ◽

10.1007/bf02967473 ◽

2001 ◽

Vol 8 (1) ◽

pp. 10-15 ◽

Cited By ~ 21

Author(s):

Sadako Akashi-Tanaka ◽

Takashi Fukutomi ◽

Kunihisa Miyakawa ◽

Takeshi Nanasawa ◽

Kaneyuki Matsuo ◽

...

Keyword(s):

Breast Cancer ◽

Computed Tomography ◽

Contrast Enhanced ◽

Intraductal Component ◽

Enhanced Computed Tomography ◽

Contrast Enhanced Computed Tomography

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Successful Use of Biweekly Gemcitabine Plus Nab-Paclitaxel in Two Male Patients With Stage IV Breast Cancer: Case Reports and Review of the Literature

American Journal of Therapeutics ◽

10.1097/mjt.0b013e3181c219e2 ◽

2011 ◽

Vol 18 (1) ◽

pp. e12-e18 ◽

Cited By ~ 1

Author(s):

Alberto J Montero ◽

Tony N Talebi ◽

Ying Zhu ◽

Kevin D Branch ◽

Grant T Goldsberry ◽

...

Keyword(s):

Breast Cancer ◽

Case Reports ◽

Stage Iv ◽

Breast Cancer Case ◽

Cancer Case ◽

Review Of The Literature ◽

Stage Iv Breast Cancer ◽

Male Patients

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Intermittent Letrozole Therapy for Metastatic Breast Cancer: Case Reports and Literature Review

Clinical Breast Cancer ◽

10.1016/j.clbc.2013.10.009 ◽

2014 ◽

Vol 14 (2) ◽

pp. e41-e45 ◽

Cited By ~ 2

Author(s):

Lei Fan ◽

Pedro E.R. Liedke ◽

Steven J. Isakoff ◽

Jessica St Louis ◽

Paula D. Ryan ◽

...

Keyword(s):

Breast Cancer ◽

Metastatic Breast Cancer ◽

Literature Review ◽

Case Reports ◽

Metastatic Breast ◽

Breast Cancer Case ◽

Cancer Case

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Lynch Syndrome and Breast Cancer: Case Reports and Literature Review

Surgical Case Reports ◽

10.31487/j.scr.2020.09.15 ◽

2020 ◽

pp. 1-3

Author(s):

Spyridon Marinopoulos ◽

Eleni Papamattheou ◽

Sofia-Dionysia Touriki ◽

Aris Giannos ◽

...

Keyword(s):

Breast Cancer ◽

Lynch Syndrome ◽

Hereditary Cancer ◽

Cancer Genomics ◽

Case Reports ◽

Breast Cancer Case ◽

Cancer Case ◽

Inherited Disease ◽

Cancer Mutations ◽

History Of

In the era of advanced cancer genomics, our knowledge of hereditary cancer mutations continues to expand. Lynch syndrome is one of the hereditary cancer predisposition syndromes associated with an increased lifelong risk of several types of cancer development, such as colorectal, endometrial, ovarian and other. This unique syndrome is an autosomal dominant inherited disease caused by mutations on EPCAM gene or on mismatch repair genes, which lead to microsatellite instability. In this article we will present three such cases visiting our clinic. They had breast cancer and a familial or personal history of malignancy. This article summarizes what we consider important about Lynch syndrome and breast cancer.

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