Substituted amides and hydrazides of 1,4-dicarboxylic acids. part 8. Synthesis and hypoglycemic activity of substituted succinic acid amides and hydrazides

1999 ◽  
Vol 33 (12) ◽  
pp. 635-637 ◽  
Author(s):  
N. V. Kolotova ◽  
A. V. Dolzhenko ◽  
V. O. Koz’minykh ◽  
V. P. Kotegov ◽  
A. T. Godina



ChemInform ◽  
2003 ◽  
Vol 34 (35) ◽  
Author(s):  
A. V. Dolzhenko ◽  
N. V. Kolotova ◽  
V. O. Koz'minykh ◽  
B. Ya. Syropyatov ◽  
V. P. Kotegov ◽  
...  


RSC Advances ◽  
2014 ◽  
Vol 4 (93) ◽  
pp. 51486-51495 ◽  
Author(s):  
Swapan Dey ◽  
Dibyendu Sain ◽  
Ashish Kumar ◽  
Chanda Kumari

Three ditopic-abiotic receptors (R1, R2 and R3) have been designed and synthesised. The receptors have been applied for the recognition of dicarboxylic acids viz. malonic, succinic, glutaric and adipic acids. Among them, succinic acid shows the highest binding efficiency to all receptors. Recognition of succinic acid is very important due to its various adverse effects on human health upon prolonged exposure.



Author(s):  
Dan Cascaval ◽  
Radu Tudose ◽  
Comeliu Oniscu

In this paper the reactive extraction of some dicarboxylic acids (oxalic acid, malonic acid, succinic acid, glutaric acid, and adipic acid) have been studied. These acids have been extracted by Amberlite LA-2 in butyl acetate using a modified extraction cell of the Lewis type. Mechanism, limiting steps, and kinetic of the mass transfer process have been settled.



2014 ◽  
Vol 32 (3) ◽  
pp. 419-422
Author(s):  
Chuanyu Sun ◽  
Yu Wang

AbstractIn this article nanoscaled polyanilines (PANI) were prepared based on template-free method in the presence of dicarboxylic acid dopants (e.g. D-tartaric acid, succinic acid, maleic acid and fumaric acid). The trans-cis isomerization of butenedioic acid played an important role in the formation of nanostructures from the plane-like to nanofibers, and the PANI doped with maleic acid (MA) had larger diameter, higher crystallinity and conductivity than PANI doped with fumaric acid (FA).





2011 ◽  
Vol 239-242 ◽  
pp. 219-222 ◽  
Author(s):  
Shao Jin Jia ◽  
Zhen Liu ◽  
Ping Kai Jiang ◽  
Jian Zhou

With an average diameter of 148-285 nm and a conductivity of 2.38E-2- 5.88 E-2S/cm, Nanoscaled polyaniline (PANI) were synthesized based on template-free method in the presence of dicarboxylic acids dopants (e.g., D-tartaric acid, Succinic acid, maleic acid and fumaric acid). Furthermore, the trans-cis isomerization of butenedioic acid plays an important role in the formation of nanostructures from plane-like to nanofibers, and PANI-MA has larger diameter, higher crystallinity and conductivity than PANI-FA.



2017 ◽  
Author(s):  
Wanyu Zhao ◽  
Kimitaka Kawamura ◽  
Siyao Yue ◽  
Lianfang Wei ◽  
Hong Ren ◽  
...  

Abstract. This study investigates the seasonal variation, molecular distribution and stable carbon isotopic composition of diacids, oxocarboxylic acids and α-dicarbonyls to better understand the sources and formation processes of fine aerosols (PM2.5) in Beijing. The concentrations of total dicarboxylic acids varied from 110 to 2580 ng m−3, whereas oxoacids (9.50–353 ng m−3) and dicarbonyls (1.50–85.9 ng m−3) were less abundant. Oxalic acid was found to be the most abundant individual species, followed by succinic acid or occasionally by terephthalic acid (tPh), a plastic burning tracer. Ambient concentrations of phthalic acid (37.9±27.3 ng m−3) and tPh (48.7±51.1 ng m−3) are larger in winter than in other seasons, illustrating that fossil fuel combustion and plastic waste incineration contribute more significantly to wintertime aerosols. The year-round mass concentration ratios of malonic acid to succinic acid (C3/C4) are relatively by comparison with those in other urban aerosols and remote marine aerosols, most of which are less than or equal to unity in Beijing; thus, the degree of photochemical formation of diacids in Beijing is insignificant. Moreover, positive correlations of some oxocarboxylic acids and α-dicarbonyls with nss-K+, a tracer for biomass burning, suggest biogenic combustion activities accounting for a large contribution of these organic acids and related precursors. The mean δ13C value of succinic acid is highest among all species with values of −17.1±3.9‰ (winter) and −17.1±2.0‰ (spring), while malonic acid is less enriched in 13C than others in autumn (−17.6±4.6‰) and summer (−18.7±4.0‰). The δ13C values of major species in the Beijing aerosols are generally lower with a wider range than those in downwind regions in the western North Pacific, which indicates that Beijing has diverse emission sources with weak photooxidation. Thus, our study demonstrates that in addition to photochemical oxidation, high abundances of diacids, oxocarboxylic acids and α-dicarbonyls in Beijing are largely associated with anthropogenic primary emissions, such as biomass burning, fossil fuel combustion, and plastic burning.



Atmosphere ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1703
Author(s):  
Kei Sato ◽  
Fumikazu Ikemori ◽  
Sathiyamurthi Ramasamy ◽  
Akihiro Fushimi ◽  
Kimiyo Kumagai ◽  
...  

To better understand precursors of dicarboxylic acids in ambient secondary organic aerosol (SOA), we studied C4–C9 dicarboxylic acids present in SOA formed from the oxidation of toluene, naphthalene, α-pinene, and isoprene. C4–C9 dicarboxylic acids present in SOA were analyzed by offline derivatization gas chromatography–mass spectrometry. We revealed that C4 dicarboxylic acids including succinic acid, maleic acid, fumaric acid, malic acid, DL-tartaric acid, and meso-tartaric acid are produced by the photooxidation of toluene. Since meso-tartaric acid barely occurs in nature, it is a potential aerosol tracer of photochemical reaction products. In SOA particles from toluene, we also detected a compound and its isomer with similar mass spectra to methyltartaric acid standard; the compound and the isomer are tentatively identified as 2,3-dihydroxypentanedioic acid isomers. The ratio of detected C4–C5 dicarboxylic acids to total toluene SOA mass had no significant dependence on the initial VOC/NOx condition. Trace levels of maleic acid and fumaric acid were detected during the photooxidation of naphthalene. Malic acid was produced from the oxidation of α-pinene and isoprene. A trace amount of succinic acid was detected in the SOA produced from the oxidation of isoprene.



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