Inhibition of free radical induced oxidative hemolysis of red blood cells by green tea polyphenols

2000 ◽  
Vol 45 (22) ◽  
pp. 2052-2056 ◽  
Author(s):  
Lanping Ma ◽  
Zaiqun Liu ◽  
Bo Zhou ◽  
Li Yang ◽  
Zhongli Liu
Keyword(s):  
Free Radical ◽  
Red Blood Cells ◽  
Green Tea ◽  
Blood Cells ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Oxidative Hemolysis

scholarly journals Synthesis and Antioxidant of Some New Pyrazolo[1,5-a]pyrimidine, Pyrazolo[5,1-b]quinazoline and Imidazo[1,2-b]pyrazole Derivatives Incorporating Phenylsulfonyl Moiety

2021 ◽  
Vol 10 (3) ◽  
pp. 2414-2428
Keyword(s):  
Antioxidant Activity ◽  
Free Radical ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Protective Effects ◽  
Oxidative Hemolysis ◽  
Elemental Analyses ◽  
Phenolic Group ◽  
High Antioxidant Activity ◽  
New Compounds

The synthesis and antioxidant of some new pyrazole analogs were described. It is achieved by the reaction of phenyl-4-(phenylsulfonyl)-1H-pyrazole-3,5-diamine (3) with different bifunctional reagents. The free radical-induced damage and the protective effects of the newly synthesized pyrazoles were studied. These new compounds inhibit the free radical-induced oxidative hemolysis of red blood cells effectively. It was found that these compounds effectively inhibit the free radical-induced oxidative hemolysis of red blood cells. Compound 5, which contain phenolic group, and 17, which bear sulfur, nitrogen atoms, and benzothiazole ring, respectively displayed high antioxidant activity. Analogs 15, 11, 10, and 9 were proved to exhibit antioxidative activity. Structures of new pyrazoles were confirmed by spectroscopic and elemental analyses and have been screened for their antioxidant activity.

Protective Effects of Resveratrol and its Analogues against Free Radical-Induced Oxidative Hemolysis of Red Blood Cells†

2010 ◽  
Vol 20 (11) ◽  
pp. 1313-1318 ◽  
Author(s):  
Jian-Guo Fang ◽  
Man Lu ◽  
Lan-Ping Ma ◽  
Li Yang ◽  
Long-Min Wu ◽  
...  
Keyword(s):  
Free Radical ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Protective Effects ◽  
Oxidative Hemolysis

Protective effects of flavonols and their glycosides against free radical-induced oxidative hemolysis of red blood cells

Life Sciences ◽  
2006 ◽  
Vol 78 (21) ◽  
pp. 2488-2493 ◽  
Author(s):  
Fang Dai ◽  
Qing Miao ◽  
Bo Zhou ◽  
Li Yang ◽  
Zhong-Li Liu
Keyword(s):  
Free Radical ◽  
Red Blood Cells ◽  
Blood Cells ◽  
Protective Effects ◽  
Oxidative Hemolysis

Antioxidant effects of green tea polyphenols on free radical initiated peroxidation of rat liver microsomes

2002 ◽  
Vol 120 (1-2) ◽  
pp. 109-117 ◽  
Author(s):  
Yu-Jun Cai ◽  
Lan-Ping Ma ◽  
Li-Fen Hou ◽  
Bo Zhou ◽  
Li Yang ◽  
...  
Keyword(s):  
Free Radical ◽  
Green Tea ◽  
Rat Liver ◽  
Liver Microsomes ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Rat Liver Microsomes ◽  
Antioxidant Effects

Significant effects of two pesticides on the bacteriostatic activity and antioxidant ability of green tea polyphenols

2020 ◽  
Author(s):  
Jin Zhang ◽  
Meng-ting Tao ◽  
Zi-yan Huang ◽  
Gui-yun Hong ◽  
Shu-guang Zhu
Keyword(s):  
Free Radical ◽  
Antioxidant Capacity ◽  
Green Tea ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Bacteriostatic Activity ◽  
Antioxidant Ability ◽  
Radical Scavenging Ability

Abstract Background: Green tea polyphenols (GTPs) have good bacteriostatic activity and antioxidant capacity, yet pesticide pollutants in tea may affect their functionality. This study aims to explore the effects of pesticide pollutants on the bacteriostasis and antioxidant ability of GTPs.Results: The bacteriostatic activity of GTPs and two pesticides (acetamiprid (ACE), diquat dibromide (DIQ)) shows some certain time characteristics. Two pesticides can affect the bacteriostatic activity of GTPs. The bacteriostatic activity of GTPs is enhanced or weakened by the two pesticides with time lengthening, i.e. time-dependent synergism or antagonism. The bacteriostatic mechanisms of the three substances and their mixtures is produced by affecting cell morphology or destroying cell structure, and the long-term antagonism of the three substances is may due to the competition of action site. In addition, the two pesticides can greatly reduce the antioxidant capacity of GTPs. ACE reduces the free radical scavenging ability of GTPs by 14%~24% and DIQ reduces the free radical scavenging ability of GTPs by 39%~63% at the experimental concentration ratios.Conclusions: Two pesticides has significant effects on the bacteriostatic activity and antioxidant ability of GTPs.

Inhibitory effects of jasmine green tea epicatechin isomers on free radical-induced lysis of red blood cells

Life Sciences ◽  
1997 ◽  
Vol 61 (4) ◽  
pp. 383-394 ◽  
Author(s):  
Anqi Zhang ◽  
Qin Yan Zhu ◽  
Yan Shun Luk ◽  
Ka Yan Ho ◽  
Kwok Pui Fung ◽  
...  
Keyword(s):  
Free Radical ◽  
Red Blood Cells ◽  
Green Tea ◽  
Blood Cells ◽  
Inhibitory Effects
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