Antioxidant effect of astragalin isolated from the leaves of Morus alba L. against free radical-induced oxidative hemolysis of human red blood cells

2013 ◽  
Vol 36 (7) ◽  
pp. 912-917 ◽  
Author(s):  
Jiwon Choi ◽  
Hyun Ju Kang ◽  
Sung Zoo Kim ◽  
Tae Oh Kwon ◽  
Seung-Il Jeong ◽  
...  
2021 ◽  
Vol 10 (3) ◽  
pp. 2414-2428

The synthesis and antioxidant of some new pyrazole analogs were described. It is achieved by the reaction of phenyl-4-(phenylsulfonyl)-1H-pyrazole-3,5-diamine (3) with different bifunctional reagents. The free radical-induced damage and the protective effects of the newly synthesized pyrazoles were studied. These new compounds inhibit the free radical-induced oxidative hemolysis of red blood cells effectively. It was found that these compounds effectively inhibit the free radical-induced oxidative hemolysis of red blood cells. Compound 5, which contain phenolic group, and 17, which bear sulfur, nitrogen atoms, and benzothiazole ring, respectively displayed high antioxidant activity. Analogs 15, 11, 10, and 9 were proved to exhibit antioxidative activity. Structures of new pyrazoles were confirmed by spectroscopic and elemental analyses and have been screened for their antioxidant activity.


2010 ◽  
Vol 20 (11) ◽  
pp. 1313-1318 ◽  
Author(s):  
Jian-Guo Fang ◽  
Man Lu ◽  
Lan-Ping Ma ◽  
Li Yang ◽  
Long-Min Wu ◽  
...  

Life Sciences ◽  
2006 ◽  
Vol 78 (21) ◽  
pp. 2488-2493 ◽  
Author(s):  
Fang Dai ◽  
Qing Miao ◽  
Bo Zhou ◽  
Li Yang ◽  
Zhong-Li Liu

2007 ◽  
Vol 45 (6) ◽  
pp. 945-952 ◽  
Author(s):  
M.F. Casado ◽  
A.L. Cecchini ◽  
A.N.C. Simão ◽  
R.D. Oliveira ◽  
R. Cecchini

2003 ◽  
Vol 17 (2) ◽  
pp. 147-151 ◽  
Author(s):  
Nobuyasu Sekiya ◽  
Naotoshi Shibahara ◽  
Iwao Sakakibara ◽  
Naoko Hattori ◽  
Hirozo Goto ◽  
...  

2015 ◽  
Vol 60 (4) ◽  
pp. 375-388 ◽  
Author(s):  
S. Mazzulla ◽  
A. Schella ◽  
D. Gabriele ◽  
N. Baldino ◽  
S. Sesti ◽  
...  

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