ACE Inhibitors and Renal Function in Hypertensive Patients

InPharma ◽  
1986 ◽  
Vol 553 (1) ◽  
pp. 15-15
Keyword(s):  
Renal Function ◽  
Ace Inhibitors ◽  
Hypertensive Patients

Deterioration of renal function in hypertensive patients with scleroderma despite blood pressure normalization with captopril

1984 ◽  
Vol 62 (15) ◽  
pp. 728-730 ◽  
Author(s):  
B. Waeber ◽  
M. -D. Schaller ◽  
J. -P. Wauters ◽  
H. R. Brunner
Keyword(s):  
Blood Pressure ◽  
Renal Function ◽  
Hypertensive Patients

Association Between ACE Inhibitors Use and Headache Caused by Nitrates Among Hypertensive Patients: Results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA)

Cephalalgia ◽  
2003 ◽  
Vol 23 (9) ◽  
pp. 901-906 ◽  
Author(s):  
G Onder ◽  
M Pahor ◽  
G Gambassi ◽  
A Federici ◽  
A Savo ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Ace Inhibitors ◽  
Ace Inhibitor ◽  
Causal Relation ◽  
Antihypertensive Agents ◽  
The Elderly ◽  
Hypertensive Patients ◽  
Academic Medical ◽  
Naranjo Algorithm ◽  
Reduced Risk

Treatment with ACE inhibitors has shown to be effective in the prophylaxis of migraine attacks. The aim of this study was to explore whether among hospitalized hypertensive patients use of ACE inhibitors may reduce the risk of headache caused by nitrates. To this end, we used the GIFA database, that includes patients admitted to academic medical centres throughout Italy. We studied 1537 patients (mean age 75 ± 10 years) receiving treatment with nitrates during a hospital stay and diagnosed with hypertension. Headaches that had a probable or definite causal relation with nitrates use based on the Naranjo algorithm were considered for this analysis. Of the total enrolled sample, 762 patients (50%) used ACE inhibitors during hospital stay. Headache caused by nitrates was recorded in 12/762 (1.6%) ACE inhibitor users and in 24/775 (3.2%) other participants ( P = 0.049). After adjusting for potential confounders, ACE inhibitors use was associated with a significantly lower risk of headache (OR 0.43; 95% Confidence Intervals: 0.20-0.90). This result was confirmed if ACE inhibitors use was compared with use of other antihypertensive agents (OR 0.44; 95% CI 0.20-0.95). In conclusion, this study suggests that among hypertensive subjects use of ACE inhibitors is associated with a reduced risk of headache caused by nitrates.

TSP-1 plasma levels in hypertensive patients with endothelial dysfunction after one year of treatment with ACE inhibitors

2017 ◽  
Vol 263 ◽  
pp. e139-e140
Author(s):  
Valentina Oana Buda ◽  
Minodora Andor ◽  
Carmen Cristescu ◽  
Mirela Voicu ◽  
Liana Suciu ◽  
...  
Keyword(s):  
Endothelial Dysfunction ◽  
Ace Inhibitors ◽  
Plasma Levels ◽  
Hypertensive Patients ◽  
One Year

BMI is associated with the development of chronic kidney diseases in hypertensive patients with normal renal function

2018 ◽  
Vol 36 (10) ◽  
pp. 2085-2091 ◽  
Author(s):  
Liling Xie ◽  
Binyan Wang ◽  
Chongfei Jiang ◽  
Xianglin Zhang ◽  
Yun Song ◽  
...  
Keyword(s):  
Renal Function ◽  
Normal Renal Function ◽  
Kidney Diseases ◽  
Chronic Kidney Diseases ◽  
Hypertensive Patients

scholarly journals Blood pressure profile, structural and functional cardiac parameters, renal function and metabolic status in hypertensive patients with chronic secondary pyelonephritis

2010 ◽  
Vol 16 (3) ◽  
pp. 256-260 ◽  
Author(s):  
M. E. Statsenko ◽  
M. V. Derevjanchenko
Keyword(s):  
Blood Pressure ◽  
Renal Function ◽  
Arterial Hypertension ◽  
Blood Pressure Monitoring ◽  
Close Relation ◽  
Pressure Profile ◽  
Upper Urinary Tract ◽  
Chronic Pyelonephritis ◽  
Metabolic Status ◽  
Hypertensive Patients

Objective. To study the blood pressure variability, morphofunctional parameters of the heart, kidney and metabolic status in hypertensive patients with secondary chronic pyelonephritis. Design and methods. The study included 110 patients: 55 patients with arterial hypertension and secondary chronic pyelonephritis, who underwent surgery for upper urinary tract, and 55 patients with essential arterial hypertension. All patients underwent 24-hour blood pressure monitoring, echocardiography; relative urine density in the morning urine portion, microalbuminuria, blood creatinine were assessed, glomerular fi ltration rate was calculated using MDRD formula. Results. Patients with arterial hypertension and chronic pyelonephritis have signifi cant changes of the blood pressure profi le, and hypertrophy and diastolic left ventricle dysfunction are more frequently observed in this group. A close relation between renal function and the state of the cardiovascular system is established. We also found higher numbers of total cholesterol, the most atherogenic fractions of cholesterol and triglycerides in this group compared to patients with essential hypertension.

scholarly journals Evalution of the effect of obesity-associated inflammation on the response to complex therapy in hypertensive elderly patients with coronary artery disease

2021 ◽  
Vol 11 (6) ◽  
pp. 143-154
Author(s):  
N. Tofan ◽  
S. Tykhonova ◽  
V. Iablonska ◽  
O. Khyzhnyak
Keyword(s):  
Coronary Artery Disease ◽  
Renal Function ◽  
Coronary Artery ◽  
Antihypertensive Therapy ◽  
Low Grade ◽  
Obese Patients ◽  
Hypertensive Patients ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients ◽  
Artery Disease

Object: to identify factors that limit the effectiveness of pharmacotherapy of hypertension (HT) with comorbid coronary artery disease (CAD) in elderly obese patients by determining laboratory and spectroscopy features related to inflammation. Material and methods: 60 patients (68.2 ± 5.9 y.o.) were observed and treated in Internal Medicine Department of University Clinic of Odessa National Medical University. Patients were divided into 2 groups. The 1st group included patients (n = 30) with body mass index (BMI) ≤25 kg/m2, HT and co-morbid CAD; the 2nd group (n = 30) - patients with BMI≥30 kg/m2, HT and with co-morbid CAD. For each patient’s group antihypertensive combination of Lisinopril and Bisoprolol was prescribed. The Laser correlation spectroscopy (LCS) was a special method for investigation. Results: before pharmacotherapy (PT) in both groups according to LCS 11-150 nm particles are prevailing. But in obese patients 75th percentile of 31-70 nm particles exceeds that one in non-obese group (56.7% vs 30.5%). During PT systolic blood pressure (SBP) value normalized in the patients of 1st group (without obesity), while in the obese patients (2nd group) SBP remained above target level. Creatinine level increased in patients of  1st group (without obesity) by 16.5 μmol / L (p <0.05) with a decrease in GFR by 17.1 ml/min/1.73 m2 (P <0.05). LCS data during PT show increase of 11-30 nm and decrease of 75-150 nm particles in non-obese patients, while in obese patients 71-150 nm particles are prevailing and 150 nm particles have appeared (p<0.05). Conclusions: 1. In elderly hypertensive patients with concomitant CAD, obesity is a factor limiting the effectiveness of complex antihypertensive therapy. 2. An increase of proportion of allergic-directed and appearance of autoimmune-directed homeostatic shifts in serum according to LCS are associated with a decrease of antihypertensive therapy efficacy in elderly hypertensive patients with CAD and obesity.  3. In hypertensive non-obese patients with CAD under the influence of complex antihypertensive therapy deteriorating of renal function is observed while in obesity renal function is not changed. 4. Homeostatic changes revealed in the second group by LCS values probably reflect manifestation of  low grade inflammatory process caused by excessive activity of adipose tissue.

Are ACE inhibitors contraindicated in hypertensive patients with a creatinine clearance below a certain level?

2019 ◽  
Vol 22 (3) ◽  
pp. 1-2
Author(s):  
Ehab Molokhia ◽  
Brandi Davis ◽  
Quy Tran ◽  
Kristina Campbell ◽  
Preston Warren
Keyword(s):  
Creatinine Clearance ◽  
Ace Inhibitors ◽  
Hypertensive Patients

scholarly journals Hypertension Management in Brazil: Usual Practice in Primary Care—A Meta-Analysis

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Rafael V. Picon ◽  
Juvenal S. Dias-da-Costa ◽  
Flavio D. Fuchs ◽  
Maria Teresa A. Olinto ◽  
Niteesh K. Choudhry ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ace Inhibitors ◽  
Meta Analysis ◽  
Random Effect ◽  
Population Based ◽  
Diabetic Patients ◽  
Economic Policies ◽  
Usual Practice ◽  
Hypertensive Patients ◽  
Medical Visits

Knowing the usual clinical practice is relevant for evaluations in health care and economic policies of management of hypertension. This study aimed to describe the usual management of hypertension in the Brazilian primary healthcare system through a systematic review and meta-analysis. The search of population-based studies conducted in Brazil was undertaken using PubMed, EMBASE, and Brazilian databases. Eligible studies were those conducted in adults with hypertension (blood pressure (BP) ≥ 140/90 mmHg or using BP lowering drugs). Three datasets’ data were analyzed: SESI study (in Brazilian workers); HIPERDIA (Brazilian Registration and Monitoring of Hypertensive and Diabetic Patients Program); and a population-based study. Meta-analysis has been performed using the fixed and random effect models. A total of 11 studies or data sets were included in the systematic review. Hypertensive individuals had, on average, 2.6 medical visits annually and 18.2% were on diuretics (n=811 hypertensive patients) and 16.2% on ACE inhibitors (n=1768 hypertensive patients). BP control rate ranged from 43.7 to 67.5%; 35.5% had measured total cholesterol and 36.5% determined fasting plasma glucose in the previous 12 months. Thiazide diuretics and ACE inhibitors were the most used BP lowering medications as single drugs, but the control rate of hypertension is insufficient.

Sign in / Sign up

Export Citation Format

Share Document