A structure–activity relationship study of phenyl sesquiterpenoids on efflux inhibition against Staphylococcus aureus

2019 ◽  
Vol 28 (8) ◽  
pp. 1308-1318
Author(s):  
Zhong-Lin Sun ◽  
Tao Liu ◽  
Simon Gibbons ◽  
Qing Mu
Keyword(s):  
Staphylococcus Aureus ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Efflux Inhibition ◽  
Relationship Study

scholarly journals Antibacterial structure–activity relationship studies of several tricyclic sulfur-containing flavonoids

2016 ◽  
Vol 12 ◽  
pp. 1065-1071 ◽  
Author(s):  
Lucian G Bahrin ◽  
Henning Hopf ◽  
Peter G Jones ◽  
Laura G Sarbu ◽  
Cornelia Babii ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Properties ◽  
Antimicrobial Properties ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Acidic Conditions ◽  
Relationship Study ◽  
Sulfur Containing

A structure–activity relationship study concerning the antibacterial properties of several halogen-substituted tricyclic sulfur-containing flavonoids has been performed. The compounds have been synthesized by cyclocondensation of the corresponding 3-dithiocarbamic flavanones under acidic conditions. The influence of different halogen substituents on the antibacterial properties has been tested against Staphylococcus aureus and Escherichia coli. Amongst the N,N-dialkylamino-substituted flavonoids, those having an N,N-diethylamino moiety exhibited good to excellent antimicrobial properties against both pathogens. Fluorine-substituted flavonoids were found to be less active than those bearing other halogen atoms.

Strategic structure-activity relationship study on a follistatin-derived myostatin inhibitory peptide

2021 ◽  
pp. 128163
Author(s):  
Mariko Saitoh ◽  
Kentaro Takayama ◽  
Yoshimi Roppongi ◽  
Takahiro Shimada ◽  
Akihiro Taguchi ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Inhibitory Peptide ◽  
Structure Activity ◽  
Relationship Study

Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain

2017 ◽  
Vol 134 ◽  
pp. 86-96 ◽  
Author(s):  
Anna Y. Belorusova ◽  
Andrea Martínez ◽  
Zoila Gándara ◽  
Generosa Gómez ◽  
Yagamare Fall ◽  
...  
Keyword(s):  
Vitamin D ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Side Chain ◽  
Vitamin D Analogs ◽  
Structure Activity ◽  
Relationship Study
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