Tubular Remodeling of Massive Cancellous Bone Graft in the Treatment of Long Bone Defects

2007 ◽  
Vol 33 (6) ◽  
pp. 654-658 ◽  
Author(s):  
Jaleel Al-Muaid ◽  
Mario Franciolli ◽  
Kaj Klaue
2010 ◽  
Vol 23 (01) ◽  
pp. 66-70 ◽  
Author(s):  
J. Shani ◽  
U. Segal

SummaryIn this case report, we describe the use of a cylindrical titanium mesh cage combined with cancellous bone graft to surgically manage large segmental bone defects in a dog. A seven-year-old, neutered male cross-breed dog, with highly comminuted fractures of the right femur and the left radius and ulna, was referred for treatment. Previous open reduction and internal fixation of these fractures had failed. Following implant removal and debridement of each bone, a 71 mm segmental femoral defect and a 27 mm segmental radial defect were present. A commercially available cylindrical titanium mesh cage was filled with ß-tricalcium phosphate crystals mixed with an equal volume of autogenous cancellous bone graft. The mesh cage was aligned with the proximal and distal parts of each bone using an intramedullary pin passing through the cage, and a locking plate was applied to the proximal and distal fracture fragments to produce compression against the titanium cage. The dog had a successful long-term clinical outcome, and radiographic examination at 22 and 63 weeks after surgery showed the formation of remodelling bridging callus that was continuous across the titanium cage in each of the fractures. Due to the relative simplicity of the technique and the favourable outcome in this case, it should be considered an option when managing comminuted fractures with large bone defects.


2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Yunhong Ma ◽  
Sanjun Gu ◽  
Qudong Yin ◽  
Haifeng Li ◽  
Yongwei Wu ◽  
...  

2010 ◽  
Vol 79 (4) ◽  
pp. 607-612 ◽  
Author(s):  
Alois Nečas ◽  
Pavel Proks ◽  
Lucie Urbanová ◽  
Robert Srnec ◽  
Ladislav Stehlík ◽  
...  

At present, attention is focused on research into possibilities of healing large bone defects by the method of mini-invasive osteosynthesis, using implantation of biomaterials and mesenchymal stem cells (MSCs). This study evaluates the healing of segmental femoral defects in miniature pigs based on the radiological determination of the callus: cortex ratio at 16 weeks after ostectomy. The size of the formed callus was significantly larger (p < 0.05) in animals after transplantation of an autogenous cancellous bone graft (group A, callus : cortex ratio of 1.77 ± 0.33) compared to animals after transplantation of cylindrical scaffold from hydroxyapatite and 0.5% collagen (group S, callus : cortex ratio of 1.08 ± 0.13), or in animals after transplantation of this scaffold seeded with MSCs (group S + MSCs, callus: cortex ratio of 1.15 ± 0.18). No significant difference was found in the size of callus between animals of group S and animals of group S + MSCs. Unlike a scaffold in the shape of the original bone column, a freely placed autogenous cancellous bone graft may allow the newly formed tissue to spread more to the periphery of the ostectomy defect. Implanted cylindrical scaffolds (with and without MSCs) support callus formation directly in the center of original bone column in segmental femoral ostectomy, and can be successfully used in the treatment of large bone defects.


1992 ◽  
Vol 05 (01) ◽  
pp. 22-25 ◽  
Author(s):  
Joanne Cockshutt ◽  
A. B. Kuzma ◽  
R. M. McLaughlin

Comminuted long bone fractures in four cats were repaired using stacked 2.0/2.7 mm cuttable plates. The plates were used as “lengthening plates", spanning cortical defects to maintain limb length. The defects were filled with autogenous cancellous bone graft. The plates did not fracture through unfilled screw holes and good to excellent limb function returned in all four cats.


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