scholarly journals Study on use of Nonvascularized Autologous Fibular Strut Graft with Autologous Cancellous Bone Graft for Treating Segmental Bone Defects of Upper Limb

2019 ◽  
Vol 7 (3) ◽  
Author(s):  
Dr Kosuri Krishna Karthik ◽  
Keyword(s):  
Bone Graft ◽  
Cancellous Bone ◽  
Upper Limb ◽  
Bone Defects ◽  
Cancellous Bone Graft ◽  
Strut Graft ◽  
Segmental Bone ◽  
Fibular Strut ◽  
Autologous Cancellous Bone Graft ◽  
Segmental Bone Defects

scholarly journals Application of multiple wrapped cancellous bone graft methods for treatment of segmental bone defects

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Yunhong Ma ◽  
Sanjun Gu ◽  
Qudong Yin ◽  
Haifeng Li ◽  
Yongwei Wu ◽  
...  
Keyword(s):  
Bone Graft ◽  
Cancellous Bone ◽  
Bone Defects ◽  
Cancellous Bone Graft ◽  
Segmental Bone ◽  
Segmental Bone Defects

Surgical management of large segmental femoral and radial bone defects in a dog

2010 ◽  
Vol 23 (01) ◽  
pp. 66-70 ◽  
Author(s):  
J. Shani ◽  
U. Segal
Keyword(s):  
Bone Graft ◽  
Cancellous Bone ◽  
Bone Defects ◽  
Radiographic Examination ◽  
Cancellous Bone Graft ◽  
Titanium Mesh ◽  
Titanium Mesh Cage ◽  
Titanium Cage ◽  
Mesh Cage ◽  
Comminuted Fractures

SummaryIn this case report, we describe the use of a cylindrical titanium mesh cage combined with cancellous bone graft to surgically manage large segmental bone defects in a dog. A seven-year-old, neutered male cross-breed dog, with highly comminuted fractures of the right femur and the left radius and ulna, was referred for treatment. Previous open reduction and internal fixation of these fractures had failed. Following implant removal and debridement of each bone, a 71 mm segmental femoral defect and a 27 mm segmental radial defect were present. A commercially available cylindrical titanium mesh cage was filled with ß-tricalcium phosphate crystals mixed with an equal volume of autogenous cancellous bone graft. The mesh cage was aligned with the proximal and distal parts of each bone using an intramedullary pin passing through the cage, and a locking plate was applied to the proximal and distal fracture fragments to produce compression against the titanium cage. The dog had a successful long-term clinical outcome, and radiographic examination at 22 and 63 weeks after surgery showed the formation of remodelling bridging callus that was continuous across the titanium cage in each of the fractures. Due to the relative simplicity of the technique and the favourable outcome in this case, it should be considered an option when managing comminuted fractures with large bone defects.

Treatment of Large Segmental Bone Defects with Reamer-Irrigator-Aspirator Bone Graft: Technique and Case Series

2010 ◽  
Vol 41 (1) ◽  
pp. 63-73 ◽  
Author(s):  
Todd A. McCall ◽  
David S. Brokaw ◽  
Bradley A. Jelen ◽  
D. Kevin Scheid ◽  
Angela V. Scharfenberger ◽  
...  
Keyword(s):  
Bone Graft ◽  
Case Series ◽  
Bone Defects ◽  
Segmental Bone ◽  
Segmental Bone Defects

scholarly journals Allogeneic Platelet Gel with Autologous Cancellous Bone Graft for the Treatment of a Large Bone Defect

2007 ◽  
Vol 39 (3) ◽  
pp. 170-174 ◽  
Author(s):  
Dragica Smrke ◽  
Borut Gubina ◽  
Dragoslav Domanoviç ◽  
Primož Rožman
Keyword(s):  
Bone Graft ◽  
Bone Defect ◽  
Cancellous Bone ◽  
Cancellous Bone Graft ◽  
Large Bone Defect ◽  
Platelet Gel ◽  
Large Bone ◽  
Autologous Cancellous Bone Graft

scholarly journals Healing of Large Segmental Bone Defect after Implantation of Autogenous Cancellous Bone Graft in Comparison to Hydroxyapatite and 0.5% Collagen Scaffold Combined with Mesenchymal Stem Cells

2010 ◽  
Vol 79 (4) ◽  
pp. 607-612 ◽  
Author(s):  
Alois Nečas ◽  
Pavel Proks ◽  
Lucie Urbanová ◽  
Robert Srnec ◽  
Ladislav Stehlík ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Bone Graft ◽  
Cancellous Bone ◽  
Bone Defects ◽  
Cancellous Bone Graft ◽  
Collagen Group ◽  
Significant Difference ◽  
Large Bone ◽  
Large Bone Defects

At present, attention is focused on research into possibilities of healing large bone defects by the method of mini-invasive osteosynthesis, using implantation of biomaterials and mesenchymal stem cells (MSCs). This study evaluates the healing of segmental femoral defects in miniature pigs based on the radiological determination of the callus: cortex ratio at 16 weeks after ostectomy. The size of the formed callus was significantly larger (p < 0.05) in animals after transplantation of an autogenous cancellous bone graft (group A, callus : cortex ratio of 1.77 ± 0.33) compared to animals after transplantation of cylindrical scaffold from hydroxyapatite and 0.5% collagen (group S, callus : cortex ratio of 1.08 ± 0.13), or in animals after transplantation of this scaffold seeded with MSCs (group S + MSCs, callus: cortex ratio of 1.15 ± 0.18). No significant difference was found in the size of callus between animals of group S and animals of group S + MSCs. Unlike a scaffold in the shape of the original bone column, a freely placed autogenous cancellous bone graft may allow the newly formed tissue to spread more to the periphery of the ostectomy defect. Implanted cylindrical scaffolds (with and without MSCs) support callus formation directly in the center of original bone column in segmental femoral ostectomy, and can be successfully used in the treatment of large bone defects.

scholarly journals Artificial Membrane Induced by Novel Biodegradable Nanofibers in the Masquelet Procedure for Treatment of Segmental Bone Defects

2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Yi-Hsun Yu ◽  
Ren-Chin Wu ◽  
Demei Lee ◽  
Che-Kang Chen ◽  
Shih-Jung Liu
Keyword(s):  
Bone Graft ◽  
Bone Defects ◽  
Artificial Membrane ◽  
Union Rate ◽  
Segmental Bone Defect ◽  
Additional Surgery ◽  
Membrane Technique ◽  
Induced Membrane Technique ◽  
Segmental Bone ◽  
Segmental Bone Defects

The Masquelet induced-membrane technique for the treatment of segmental bone defects includes a two-stage surgical procedure, and polymethylmethacrylate (PMMA) plays a major role in the treatment. However, the PMMA spacer must be surgically removed. Here, we investigated the potential of poly(lactic-co-glycolic acid) (PLGA) nanofibers, a biodegradable material to replace the PMMA spacer, allowing the bioactive membrane to be induced and the spacer to degrade without the additional surgery on a rabbit femoral segmental bone defect model. PLGA nanofibers were shown to degrade completely six weeks after implantation in the investigated animals, and a thick membrane was found to circumferentially fold around the segmental bone defects. Results from image studies demonstrated that, in the group without the bone graft, all studied femurs exhibited either nonunion or considerable malunion. In contrast, the femurs in the bone graft group had a high union rate without considerable deformities. Histological examinations suggested that the membranous tissue in this group was rich in small blood vessels and the expression of BMP2 and VEGF increased. Our results demonstrate that the biodegradable PLGA nanofibers may be useful for replacing the PMMA spacer as the bioactive-membrane inducer, facilitating the process of healing and removing the need for repeated surgeries.

Sign in / Sign up

Export Citation Format

Share Document