scholarly journals Research of the effects of autologous cancellous bone graft and hyaluronic acidon the healing of bone defects experimentally induced in rabbits

2016 ◽  
Vol 40 ◽  
pp. 374-381 ◽  
Author(s):  
Aydın SAĞLIYAN ◽  
Mehmet Cengiz HAN ◽  
Enis KARABULUT ◽  
Mustafa ÖZKARACA
Keyword(s):  
Bone Graft ◽  
Cancellous Bone ◽  
Bone Defects ◽  
Cancellous Bone Graft ◽  
Autologous Cancellous Bone Graft ◽  
Experimentally Induced

Surgical management of large segmental femoral and radial bone defects in a dog

2010 ◽  
Vol 23 (01) ◽  
pp. 66-70 ◽  
Author(s):  
J. Shani ◽  
U. Segal
Keyword(s):  
Bone Graft ◽  
Cancellous Bone ◽  
Bone Defects ◽  
Radiographic Examination ◽  
Cancellous Bone Graft ◽  
Titanium Mesh ◽  
Titanium Mesh Cage ◽  
Titanium Cage ◽  
Mesh Cage ◽  
Comminuted Fractures

SummaryIn this case report, we describe the use of a cylindrical titanium mesh cage combined with cancellous bone graft to surgically manage large segmental bone defects in a dog. A seven-year-old, neutered male cross-breed dog, with highly comminuted fractures of the right femur and the left radius and ulna, was referred for treatment. Previous open reduction and internal fixation of these fractures had failed. Following implant removal and debridement of each bone, a 71 mm segmental femoral defect and a 27 mm segmental radial defect were present. A commercially available cylindrical titanium mesh cage was filled with ß-tricalcium phosphate crystals mixed with an equal volume of autogenous cancellous bone graft. The mesh cage was aligned with the proximal and distal parts of each bone using an intramedullary pin passing through the cage, and a locking plate was applied to the proximal and distal fracture fragments to produce compression against the titanium cage. The dog had a successful long-term clinical outcome, and radiographic examination at 22 and 63 weeks after surgery showed the formation of remodelling bridging callus that was continuous across the titanium cage in each of the fractures. Due to the relative simplicity of the technique and the favourable outcome in this case, it should be considered an option when managing comminuted fractures with large bone defects.

scholarly journals Allogeneic Platelet Gel with Autologous Cancellous Bone Graft for the Treatment of a Large Bone Defect

2007 ◽  
Vol 39 (3) ◽  
pp. 170-174 ◽  
Author(s):  
Dragica Smrke ◽  
Borut Gubina ◽  
Dragoslav Domanoviç ◽  
Primož Rožman
Keyword(s):  
Bone Graft ◽  
Bone Defect ◽  
Cancellous Bone ◽  
Cancellous Bone Graft ◽  
Large Bone Defect ◽  
Platelet Gel ◽  
Large Bone ◽  
Autologous Cancellous Bone Graft

scholarly journals Application of multiple wrapped cancellous bone graft methods for treatment of segmental bone defects

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Yunhong Ma ◽  
Sanjun Gu ◽  
Qudong Yin ◽  
Haifeng Li ◽  
Yongwei Wu ◽  
...  
Keyword(s):  
Bone Graft ◽  
Cancellous Bone ◽  
Bone Defects ◽  
Cancellous Bone Graft ◽  
Segmental Bone ◽  
Segmental Bone Defects

scholarly journals Healing of Large Segmental Bone Defect after Implantation of Autogenous Cancellous Bone Graft in Comparison to Hydroxyapatite and 0.5% Collagen Scaffold Combined with Mesenchymal Stem Cells

2010 ◽  
Vol 79 (4) ◽  
pp. 607-612 ◽  
Author(s):  
Alois Nečas ◽  
Pavel Proks ◽  
Lucie Urbanová ◽  
Robert Srnec ◽  
Ladislav Stehlík ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Bone Graft ◽  
Cancellous Bone ◽  
Bone Defects ◽  
Cancellous Bone Graft ◽  
Collagen Group ◽  
Significant Difference ◽  
Large Bone ◽  
Large Bone Defects

At present, attention is focused on research into possibilities of healing large bone defects by the method of mini-invasive osteosynthesis, using implantation of biomaterials and mesenchymal stem cells (MSCs). This study evaluates the healing of segmental femoral defects in miniature pigs based on the radiological determination of the callus: cortex ratio at 16 weeks after ostectomy. The size of the formed callus was significantly larger (p < 0.05) in animals after transplantation of an autogenous cancellous bone graft (group A, callus : cortex ratio of 1.77 ± 0.33) compared to animals after transplantation of cylindrical scaffold from hydroxyapatite and 0.5% collagen (group S, callus : cortex ratio of 1.08 ± 0.13), or in animals after transplantation of this scaffold seeded with MSCs (group S + MSCs, callus: cortex ratio of 1.15 ± 0.18). No significant difference was found in the size of callus between animals of group S and animals of group S + MSCs. Unlike a scaffold in the shape of the original bone column, a freely placed autogenous cancellous bone graft may allow the newly formed tissue to spread more to the periphery of the ostectomy defect. Implanted cylindrical scaffolds (with and without MSCs) support callus formation directly in the center of original bone column in segmental femoral ostectomy, and can be successfully used in the treatment of large bone defects.

Beta-tricalcium phosphate as a synthetic cancellous bone graft in veterinary orthopaedics

2006 ◽  
Vol 19 (04) ◽  
pp. 196-204 ◽  
Author(s):  
C. Díaz-Bertrana ◽  
P. Lafuente ◽  
P. Fontecha ◽  
I. Durall ◽  
J. Franch
Keyword(s):  
Bone Graft ◽  
Cancellous Bone ◽  
Tricalcium Phosphate ◽  
Bone Fractures ◽  
Bone Defects ◽  
Cancellous Bone Graft ◽  
Non Union ◽  
Defect Healing ◽  
Metacarpal Bones ◽  
Clinical Cases

SummaryThe clinical use of β-tricalcium phosphate (β-TCP) as a synthetic cancellous bone graft in veterinary orthopaedics is herein reported. The retrospective study was based on 13 clinical cases belonging to 11 dogs and one cat. The weights of the dogs ranged from 3.4 to 48 kg. One female cat weighing 3.5 kg completed the study. The clinical cases were six arthrodeses (four carpal, two tarsal), one hypertrophic non-union (femur), one atrophic non-union (metacarpal bones) and five long-bone fractures (two femurs, one tibia, two radii) possessing subcritical-sized bone defects. The β-TCP used in this study was presented as irregular interconnected-porous granules and was placed in the bone defects after mixing it with fresh blood. Bone healing was achieved at between eight and 12 weeks in all clinical cases except for the case of the chronic atrophic nonunion in which only one of the four metacarpal bones healed. In the 12 successful cases, the bone defect grafted with β-TCP showed a radiological bone ingrowth of 100% (10 cases), 90% (one case) and 75% (one case). The complete lack of tissue adverse effects in our series, and the good defect healing, allows us to hypothesise that β-TCP can be successfully used as a synthetic bone graft in bone defects with good local biological conditions and where osteoconduction is especially needed for assuring a structural scaffold for newbone ingrowth. When, in addition to osteoconduction, osteoinduction and osteogenesis are necessary for defect healing, the fresh cancellous bone graft remains the gold standard in veterinary orthopaedics.

Arthrodesis of the Distal Two Tarsal Joints in the Horse Using Perforated Stainless Steel Cylinders and Cancellous Bone Graft

1991 ◽  
Vol 4 (01) ◽  
pp. 21-27 ◽  
Author(s):  
R. M. Archer ◽  
R. K. Schneider
Keyword(s):  
Stainless Steel ◽  
Bone Graft ◽  
Cancellous Bone ◽  
Cancellous Bone Graft ◽  
The Third ◽  
Partial Fusion

SummaryTwo perforated stainless steel cylinders and autogenous cancellous bone were implanted into each of the distal intertarsal and tarsometatarsal joints of seven horses. In two control horses holes were drilled into each joint and autogenous cancellous bone was implanted without stainless steel cylinders. Horses which had cylinders implanted in the distal tarsal joints exhibited less lameness and were more comfortable following surgery than were the control horses. Fracture of the third tarsal, central tarsal, or third metatarsal occurred in five of the seven horses implanted with stainless steel cylinders within 45 days of surgery. Two implanted horses and two control horses were observed for five months after surgery. Partial fusion of the distal tarsal joints occurred in all four horses. Control horses were more lame than the implanted horses and developed a large bony exostosis over the medial distal tarsus.

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