scholarly journals Glucose-responsive beta cells in islets isolated from a patient with long-standing type 1 diabetes mellitus

Diabetologia ◽  
2010 ◽  
Vol 54 (1) ◽  
pp. 200-202 ◽  
Author(s):  
J. N. Walker ◽  
P. R. V. Johnson ◽  
M. Shigeto ◽  
S. J. Hughes ◽  
A. Clark ◽  
...  
2017 ◽  
Vol 174 (13) ◽  
pp. 2074-2084 ◽  
Author(s):  
Raghu Ganugula ◽  
Meenakshi Arora ◽  
Patcharawalai Jaisamut ◽  
Ruedeekorn Wiwattanapatapee ◽  
Heather G Jørgensen ◽  
...  

2010 ◽  
Vol 13 (1) ◽  
pp. 45-49
Author(s):  
Elena Vladimirovna Pekareva ◽  
Tatiana Vasil'evna Nikonova ◽  
Olga Mikhailovna Smirnova

Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes inpatients with DM1.


2010 ◽  
Vol 13 (1) ◽  
pp. 126-128
Author(s):  
Elena Alexandrovna Kharlashina ◽  
Olga Sergeevna Shapoval'yants ◽  
Elena Vladimirovna Pekareva ◽  
Tatiana Vasil'evna Nikonova

Diabetes mellitus (DM) is a polygenous multifactor disease that may be triggered by a viral infection that causes death of beta-cells by at least two mechanisms,virus-mediated autoimmunity and direct cell injury. A case of DM1 following infectious mononucleosis is described to illustrate the necessityof a combined approach to the examination of patients and prescription of treatment.


2013 ◽  
Author(s):  
Blake M. Lancaster ◽  
Ashley M. Lugo ◽  
Lynne Clure ◽  
Kate S. Holman ◽  
Ryan T. Thorson

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