scholarly journals Bedside assessment of the effects of positive end-expiratory pressure on lung inflation and recruitment by the helium dilution technique and electrical impedance tomography

2016 ◽  
Vol 42 (10) ◽  
pp. 1576-1587 ◽  
Author(s):  
Tommaso Mauri ◽  
Nilde Eronia ◽  
Cecilia Turrini ◽  
Marta Battistini ◽  
Giacomo Grasselli ◽  
...  
1998 ◽  
Vol 84 (2) ◽  
pp. 726-732 ◽  
Author(s):  
Andy Adler ◽  
Norihiro Shinozuka ◽  
Yves Berthiaume ◽  
Robert Guardo ◽  
Jason H. T. Bates

Adler, Andy, Norihiro Shinozuka, Yves Berthiaume, Robert Guardo, and Jason H. T. Bates. Electrical impedance tomography can monitor dynamic hyperinflation in dogs. J. Appl. Physiol. 84(2): 726–732, 1998.—We assessed in eight dogs the accuracy with which electrical impedance tomography (EIT) can monitor changes in lung volume by comparing the changes in mean lung conductivity obtained with EIT to changes in esophageal pressure (Pes) and to airway opening pressure (Pao) measured after airway occlusion. The average volume measurement errors were determined: 26 ml for EIT; 35 ml for Pao; and 54 ml for Pes. Subsequently, lung inflation due to applied positive end-expiratory pressure was measured by EIT (ΔVEIT) and Pao (ΔVPao) under both inflation and deflation conditions. Whereas ΔVPaowas equal under both conditions, ΔVEITwas 28 ml greater during deflation than inflation, indicating that EIT is sensitive to lung volume history. The average inflation ΔVEITwas 67.7 ± 78 ml greater than ΔVPao, for an average volume increase of 418 ml. Lung inflation due to external expiratory resistance was measured during ventilation by EIT (ΔVEIT,vent) and Pes (ΔVPes,vent) and at occlusion by EIT (ΔVEIT,occl), Pes, and Pao. The average differences between EIT estimates and ΔVEIT,occlwere 5.8 ± 44 ml for ΔVEIT,ventand 49.5 ± 34 ml for ΔVEIT,occl. The average volume increase for all dogs was 442.2 ml. These results show that EIT can provide usefully accurate estimates of changes in lung volume over an extended time period and that the technique has promise as a means of conveniently and noninvasively monitoring lung hyperinflation.


2019 ◽  
Vol 8 (8) ◽  
pp. 1161 ◽  
Author(s):  
Thomas Muders ◽  
Benjamin Hentze ◽  
Philipp Simon ◽  
Felix Girrbach ◽  
Michael R.G. Doebler ◽  
...  

Avoiding tidal recruitment and collapse during mechanical ventilation should reduce the risk of lung injury. Electrical impedance tomography (EIT) enables detection of tidal recruitment by measuring regional ventilation delay inhomogeneity (RVDI) during a slow inflation breath with a tidal volume (VT) of 12 mL/kg body weight (BW). Clinical applicability might be limited by such high VTs resulting in high end-inspiratory pressures (PEI) during positive end-expiratory pressure (PEEP) titration. We hypothesized that RVDI can be obtained with acceptable accuracy from reduced slow inflation VTs. In seven ventilated pigs with experimental lung injury, tidal recruitment was quantified by computed tomography at PEEP levels changed stepwise between 0 and 25 cmH2O. RVDI was measured by EIT during slow inflation VTs of 12, 9, 7.5, and 6 mL/kg BW. Linear correlation of tidal recruitment and RVDI was excellent for VTs of 12 (R2 = 0.83, p < 0.001) and 9 mL/kg BW (R2 = 0.83, p < 0.001) but decreased for VTs of 7.5 (R2 = 0.76, p < 0.001) and 6 mL/kg BW (R2 = 0.71, p < 0.001). With any reduction in slow inflation VT, PEI decreased at all PEEP levels. Receiver-Operator-Characteristic curve analyses revealed that RVDI-thresholds to predict distinct amounts of tidal recruitment differ when obtained from different slow inflation VTs. In conclusion, tidal recruitment can sufficiently be monitored by EIT-based RVDI-calculation with a slow inflation of 9 mL/kg BW.


2020 ◽  
Vol 60 ◽  
pp. 38-44 ◽  
Author(s):  
Floriane Puel ◽  
Laure Crognier ◽  
Christelle Soulé ◽  
Fanny Vardon-Bounes ◽  
Stéphanie Ruiz ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Sébastien Gibot ◽  
Marie Conrad ◽  
Guilhem Courte ◽  
Aurélie Cravoisy

Introduction: The best way to titrate the positive end-expiratory pressure (PEEP) in patients suffering from acute respiratory distress syndrome is still matter of debate. Electrical impedance tomography (EIT) is a non-invasive technique that could guide PEEP setting based on an optimized ventilation homogeneity.Methods: For this study, we enrolled the patients with 2019 coronavirus disease (COVID-19)-related acute respiratory distress syndrome (ARDS), who required mechanical ventilation and were admitted to the ICU in March 2021. Patients were monitored by an esophageal catheter and a 32-electrode EIT device. Within 48 h after the start of mechanical ventilation, different levels of PEEP were applied based upon PEEP/FiO2 tables, positive end-expiratory transpulmonary (PL)/ FiO2 table, and EIT. Respiratory mechanics variables were recorded.Results: Seventeen patients were enrolled. PEEP values derived from EIT (PEEPEIT) were different from those based upon other techniques and has poor in-between agreement. The PEEPEIT was associated with lower plateau pressure, mechanical power, transpulmonary pressures, and with a higher static compliance (Crs) and homogeneity of ventilation.Conclusion: Personalized PEEP setting derived from EIT may help to achieve a more homogenous distribution of ventilation. Whether this approach may translate in outcome improvement remains to be investigated.


Sign in / Sign up

Export Citation Format

Share Document