Preoperative clinical, demographic, and urodynamic measures associated with failure to demonstrate urodynamic stress incontinence in women enrolled in two randomized clinical trials of surgery for stress urinary incontinence

AbstractThe study aims to identify predictors for de novo stress urinary incontinence (SUI) following Elevate mesh surgery. A total of 164 women who underwent Elevate mesh surgeries between November 2011 and February 2014 in a single center were included. Seventy-three women were excluded due to preoperative incontinence or concomitant mid-urethral sling surgery. Fourteen others were excluded due to incomplete medical records. Fisher’s exact test and χ2 test were applied. The univariate logistic regression was used for odds ratios. Of the 77 continent women, 24 (31.2%) experienced de novo SUI after the operation. Significantly more women with de novo SUI were over the age of 64 years (75.0% vs. 47.2%, p = 0.023, OR 3.36, 95% CI 1.15–9.79). Preoperative occult urodynamic stress incontinence (29.2% vs. 3.8%, p = 0.003, OR 10.0, 95% CI 2.0–50.0) and previous SUI history (41.7% vs. 7.6%, p = 0.001, OR 9.1, 95% CI 2.38–33.3) were 2 other predictors of de novo SUI postoperatively. In conclusion, age over 64 years old, occult urodynamic stress incontinence, and previous history of SUI are 3 significant predictors for de novo SUI following the single-incision mesh surgeries.

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The “1-3-5 cough test”: comparing the severity of urodynamic stress incontinence with severity measures of subjective perception of stress urinary incontinence

International Urogynecology Journal ◽

10.1007/s00192-015-2808-4 ◽

2015 ◽

Vol 27 (3) ◽

pp. 419-425 ◽

Cited By ~ 4

Author(s):

Themos Grigoriadis ◽

George Giannoulis ◽

Dimitris Zacharakis ◽

Athanasios Protopapas ◽

Linda Cardozo ◽

...

Keyword(s):

Urinary Incontinence ◽

Stress Urinary Incontinence ◽

Stress Incontinence ◽

Urodynamic Stress Incontinence ◽

Subjective Perception ◽

Cough Test

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The effectiveness of biofeedback in treatment of women with stress urinary incontinence: a systematic review

Revista Brasileira de Saúde Materno Infantil ◽

10.1590/s1519-38292011000300002 ◽

2011 ◽

Vol 11 (3) ◽

pp. 217-225 ◽

Cited By ~ 1

Author(s):

Leila Maria Alvares Barbosa ◽

Deniele Bezerra Lós ◽

Ivson Bezerra da Silva ◽

Caroline W. S. Ferreira Anselmo

Keyword(s):

Clinical Trials ◽

Urinary Incontinence ◽

Stress Urinary Incontinence ◽

Pelvic Floor ◽

Randomized Clinical Trials ◽

Pelvic Floor Muscle Training ◽

Physical Therapist ◽

Pelvic Floor Muscle ◽

Muscle Training ◽

Significant Difference

OBJECTIVES: to assess whether pelvic-floor muscle training associated with biofeedback is more effective in the treatment of women with stress urinary incontinence, when compared to exercise alone. METHODS: a research of articles published in the last 20 years in Lilacs, PubMed and SCIRUS databases, using the descriptors "urinary incontinence, stress" and "biofeedback" was conducted. Randomized clinical trials comparing pelvic-floor muscle training with and without biofeedback were included. RESULTS: the study involved three randomized clinical trials involving 169 patients. A physical therapist was responsible for conducting the treatment using electromyographic or pressure biofeedback, and exercises were performed in the clinic or at home. The assessment methods, treatment times and protocols used were heterogeneous. Statistical analysis and rates of cure/improvement were similar between the groups of articles analyzed. Two studies had a score 8, and the third had 6 points according to PEDro's Scale. CONCLUSIONS: examination of the studies found suggests that adding biofeedback to pelvic-floor muscle training appears not to bring about a significant difference in terms of the success of treatment, when compared to perineal exercises performed in isolation.

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Minimally Invasive Therapies for Female Stress Urinary Incontinence: the Current Status of Bioinjectables/New Devices (Adjustable Continence Therapy, Urethral Submucosal Collagen Denaturation by Radiofrequency)

The Scientific World JOURNAL ◽

10.1100/tsw.2009.53 ◽

2009 ◽

Vol 9 ◽

pp. 466-478 ◽

Cited By ~ 10

Author(s):

Simone Crivellaro ◽

John J. Smith

Keyword(s):

Clinical Trials ◽

Urinary Incontinence ◽

Clinical Practice ◽

Stress Urinary Incontinence ◽

Minimally Invasive ◽

Emerging Technologies ◽

Current Status ◽

Female Stress Urinary Incontinence ◽

Salvage Procedure ◽

Collagen Denaturation

The aim of this review is to provide an update on the current status of evolving minimally invasive therapies for stress urinary incontinence. Bioinjectables have been available for some time and their current status is reviewed. The adjustable continence device has been used as a salvage procedure for females for a number of years in clinical trials, yet many are unfamiliar with it. Lastly, radiofrequency via a transurethral route has also been utilized in small numbers and will be updated. These later two emerging technologies need further exposure to better define their role in our clinical practice.

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Can reducing the number of stitches compromise the outcome of laparoscopic Burch surgery in the treatment of stress urinary incontinence? Systematic review and meta-analysis

Revista do Colégio Brasileiro de Cirurgiões ◽

10.1590/0100-69912017006011 ◽

2017 ◽

Vol 44 (6) ◽

pp. 649-654 ◽

Cited By ~ 2

Author(s):

RICARDO JOSÉ SOUZA ◽

JOSÉ ANACLETO DUTRA RESENDE JÚNIOR ◽

CLARICE GUIMARÃES MIGLIO ◽

LEILA CRISTINA SOARES BROLLO ◽

MARCO AURÉLIO PINHO OLIVEIRA ◽

...

Keyword(s):

Systematic Review ◽

Urinary Incontinence ◽

Stress Urinary Incontinence ◽

Randomized Clinical Trials ◽

Meta Analysis ◽

P Value ◽

Open Technique ◽

Control Series ◽

One Year ◽

Cure Rates

ABSTRACT The retropubic colposuspension in the treatment of stress urinary incontinence has been rescued with the laparoscopic route. Some authors have reduced the number of stitches, from two to one, due to the difficulty of suturing by this route. To what extent can this modification compromise outcome? To answer this question, we performed a systematic review and meta-analysis on the MEDLINE/PubMed and LILACS/SciELO databases between 1990 and 2015. We included randomized clinical trials, cohort studies and case-control series comparing laparoscopic versus open Burch, and two versus one stitch in laparoscopic Burch, with a minimum follow-up of one year. Fourteen studies compared laparoscopic versus open Burch, in which we found no differences between the two techniques using one stitch (Relative Risk - RR - of 0.94, 95% CI 0.79-1.11) and two stitches (RR of 1.03, 95% CI 0.97-1.10). Only one study compared one stitch versus two stitches in laparoscopic Burch, with cure rates of 68% versus 87%, respectively (p-value= 0.02). We did not identify differences when compared open technique with two stitches versus laparoscopic with one stitch and open technique with two stitches versus laparoscopic with two. The study comparing one versus two laparoscopic stitches demonstrated superior results with the latter. Although there is no robust evidence, when Burch surgery is performed laparoscopically, the use of two stitches seems to be the best option.

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Stem cell applications in regenerative medicine for stress urinary incontinence: A review of effectiveness based on clinical trials

Arab Journal of Urology ◽

10.1080/2090598x.2020.1750864 ◽

2020 ◽

Vol 18 (3) ◽

pp. 194-205

Author(s):

Bara Barakat ◽

Knut Franke ◽

Samer Schakaki ◽

Sameh Hijazi ◽

Viktoria Hasselhof ◽

...

Keyword(s):

Clinical Trials ◽

Urinary Incontinence ◽

Stem Cell ◽

Stress Urinary Incontinence ◽

Regenerative Medicine

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What causes stress incontinence: Fallacies, fascias and facts

Canadian Urological Association Journal ◽

10.5489/cuaj.1458 ◽

2012 ◽

Vol 6 (5-S2) ◽

pp. 114 ◽

Cited By ~ 5

Author(s):

John DeLancey

Keyword(s):

Urinary Incontinence ◽

Stress Urinary Incontinence ◽

Stress Incontinence ◽

Traditional View ◽

Causative Role ◽

Novel Therapies ◽

Urethral Support ◽

Urethral Function

The traditional view of the pathophysiology of stress urinary incontinence (SUI) was that a loss of urethral support was the primary abnormality present. Recent research has challenged this hypothesis, demonstrating that impaired urethral function plays the key causative role. Improving our understanding of the underlying pathologic mechanisms is important to identifying the cause of treatment failures and for developing novel therapies to treat SUI.

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