Processing and Analysis of In Vivo High-Resolution MR Images of Trabecular Bone for Longitudinal Studies: Reproducibility of Structural Measures and Micro-Finite Element Analysis Derived Mechanical Properties

2002 ◽  
Vol 13 (4) ◽  
pp. 278-287 ◽  
Author(s):  
D. C. Newitt ◽  
B. van Rietbergen ◽  
S. Majumdar
2002 ◽  
Vol 13 (1) ◽  
pp. 6-17 ◽  
Author(s):  
B. van Rietbergen ◽  
G. von Ingersleben ◽  
C. Chesnut ◽  
B. MacDonald ◽  
H. K. Genant ◽  
...  

1997 ◽  
Vol 272 (1) ◽  
pp. H425-H437 ◽  
Author(s):  
M. J. Vonesh ◽  
C. H. Cho ◽  
J. V. Pinto ◽  
B. J. Kane ◽  
D. S. Lee ◽  
...  

A method employing intravascular ultrasound (IVUS) and simultaneous hemodynamic measurements, with resultant finite element analysis (FEA) of accurate three-dimensional IVUS reconstructions (3-DR), was developed to estimate the regional distribution of arterial elasticity. Human peripheral arterial specimens (iliac and femoral, n = 7) were collected postmortem and perfused at three static transmural pressures: 80, 120, and 160 mmHg. At each pressure, IVUS data were collected at 2.0-mm increments through a 20.0-mm segment and used to create an accurate 3-DR. Mechanical properties were determined over normotensive and hypertensive ranges. An FEA and optimization procedure was implemented in which the elemental elastic modulus was scaled to minimize the displacement error between the computer-predicted and actual deformations. The “optimized” elastic modulus (Eopt) represents an estimate of the component element material stiffness. A dimensionless variable (beta), quantifying structural stiffness, was computed. Eopt of nodiseased tissue regions (n = 80) was greater than atherosclerotic regions (n = 88) for both normotensive (Norm) and hypertensive (Hyp) pressurization: Norm, 9.3 +/- 0.98 vs. 3.5 +/- 0.30; Hyp, 11.3 +/- 0.72 vs. 8.5 +/- 0.47, respectively (mean +/- SE x 10(6) dyn/cm2; P < 0.01 vs. nondiseased). No differences in beta between nondiseased and atherosclerotic tissue were noted at Norm pressurization. With Hyp pressurization, beta of atherosclerotic regions were greater than nondiseased regions: 21.5 +/- 2.21 vs. 14.0 +/- 2.11, respectively (P < 0.03). This method provides a means to identify regional in vivo variations in mechanical properties of arterial tissue.


2013 ◽  
Vol 40 (5) ◽  
pp. 052303 ◽  
Author(s):  
Ning Zhang ◽  
Jeremy F. Magland ◽  
Chamith S. Rajapakse ◽  
Yusuf A. Bhagat ◽  
Felix W. Wehrli

2001 ◽  
Vol 57 (11) ◽  
pp. 1372-1379
Author(s):  
JUN KOHNO ◽  
MASAKO ITO ◽  
MIKA KOHNO ◽  
TOMOKO NAKATA ◽  
KIYOTAKA FURUYAMA ◽  
...  

2009 ◽  
Vol 27 (10) ◽  
pp. 1263-1271 ◽  
Author(s):  
Chamith S. Rajapakse ◽  
Jeremy Magland ◽  
X. Henry Zhang ◽  
X. Sherry Liu ◽  
Suzanne L. Wehrli ◽  
...  

Materials ◽  
2020 ◽  
Vol 13 (14) ◽  
pp. 3063 ◽  
Author(s):  
Magdalena Lisiak-Myszke ◽  
Dawid Marciniak ◽  
Marek Bieliński ◽  
Hanna Sobczak ◽  
Łukasz Garbacewicz ◽  
...  

In recent years in the field of biomechanics, the intensive development of various experimental methods has been observed. The implementation of virtual studies that for a long time have been successfully used in technical sciences also represents a new trend in dental engineering. Among these methods, finite element analysis (FEA) deserves special attention. FEA is a method used to analyze stresses and strains in complex mechanical systems. It enables the mathematical conversion and analysis of mechanical properties of a geometric object. Since the mechanical properties of the human skeleton cannot be examined in vivo, a discipline in which FEA has found particular application is oral and maxillofacial surgery. In this review we summarize the application of FEA in particular oral and maxillofacial fields such as traumatology, orthognathic surgery, reconstructive surgery and implantology presented in the current literature. Based on the available literature, we discuss the methodology and results of research where FEA has been used to understand the pathomechanism of fractures, identify optimal osteosynthesis methods, plan reconstructive operations and design intraosseous implants or osteosynthesis elements. As well as indicating the benefits of FEA in mechanical parameter analysis, we also point out the assumptions and simplifications that are commonly used. The understanding of FEA’s opportunities and advantages as well as its limitations and main flaws is crucial to fully exploit its potential.


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