Psychedelics for the treatment of depression, anxiety, and existential distress in patients with a terminal illness: a systematic review

Author(s):  
Nina Schimmel ◽  
Joost J. Breeksema ◽  
Sanne Y. Smith-Apeldoorn ◽  
Jolien Veraart ◽  
Wim van den Brink ◽  
...  
Author(s):  
Amado Rivero-Santana ◽  
Lilisbeth Perestelo-Perez ◽  
Yolanda Alvarez-Perez ◽  
Vanesa Ramos-Garcia ◽  
Andrea Duarte-Díaz ◽  
...  

Author(s):  
Esteve Gudayol-Ferré ◽  
Maribel Peró-Cebollero ◽  
Andrés A. González-Garrido ◽  
Joan Guàrdia-Olmos

2021 ◽  
Author(s):  
Zixuan Zhang ◽  
Shaoyuan Li ◽  
Hong Meng ◽  
Yifei Wang ◽  
Yue Zhang ◽  
...  

Author(s):  
William S. Breitbart

Spirituality is important in the lives of patients with serious illnesses. Terminally patients may experience a number of spiritual issues, including lack of meaning, guilt, shame, hopelessness, loss of dignity, loneliness, anger toward God, abandonment by God, feeling out of control, grief, and spiritual suffering. Assessment of a patient’s spiritual beliefs, assessing the importance of spirituality in his or her life, exploring whether he or she belongs to a spiritual community, and offering chaplaincy referral or connection with the patient’s religious or spiritual leaders comprise essential components of a spiritual assessment. Psycho-oncologists should seek both specialized training, as well as referrals to appropriate sources, in order to help patients deal more effectively with the often complicated and painful spiritual issues that arise as a consequence of serious illness. Existential concerns are intrinsic to the human experience of facing mortality in palliative care settings. Patients diagnosed with terminal cancer often confront universal existential issues such as death anxiety, isolation, and meaninglessness. Psycho-oncologists must therefore be familiar with these existential concerns, their manifestations, and approaches to deal with existential issues. Psycho-oncologists have the unique ability to use a variety of psychotherapeutic interventions to alleviate existential distress in palliative care settings including cognitive therapies to help patients and families modify their appraisal of their lives with terminal illness, known as cognitive restructuring, life review techniques to facilitate a constructive reappraisal of life events, dignity-conserving therapies, and meaning-centered therapies have been shown to effectively reduce existential distress in this patient population.


Author(s):  
Sohrab Amiri ◽  
Sepideh Behnezhad

Background and objective Depression is a common mental disorder that leads to undesirable consequences. The study of the role of depression in disability pension can provide valuable insights. This study was conducted with the goal of systematic review and meta-analysis of the relationship between depression and disability pension. Methods PubMed, Scopus, PsycInfo, and Google Scholar databases were systematically searched until March 2018. Fifteen prospective cohort studies were selected and included in the meta-analysis. The random-effects method was used to combine the studies. Subgroup analysis was performed, and publication bias was also examined. Results Depression was a risk factor for disability pension (pooled risk ratio =1.68 and 95% confidence interval = 1.50–1.88). In men, pooled risk ratio was 1.82 for the effect of depression on the risk of disability pension (95% confidence interval = 1.45–2.28). In women, pooled risk ratio was 1.62 (95% confidence interval = 1.31–2.02). The results showed that there is publication bias. Conclusions Depression is a factor for retirement due to disability. Therefore, the prevention and treatment of depression can reduce socioeconomic and psychological consequences imposed on society.


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