Personalising drug safety—results from the multi-centre prospective observational study on Adverse Drug Reactions in Emergency Departments (ADRED)

2019 ◽  
Vol 76 (3) ◽  
pp. 439-448 ◽  
Author(s):  
Katja S. Just ◽  
Harald Dormann ◽  
Miriam Böhme ◽  
Marlen Schurig ◽  
Katharina L. Schneider ◽  
...  
Keyword(s):  
Observational Study ◽  
Adverse Drug Reactions ◽  
Drug Safety ◽  
Emergency Departments ◽  
Prospective Observational Study ◽  
Drug Reactions

scholarly journals Incidence of adverse drug reactions in a paediatric ward of a Malaysian hospital: A prospective observational study

2018 ◽  
Vol 17 (7) ◽  
pp. 1423
Author(s):  
Muslimah Ithnin ◽  
Mohd Dzulkhairi Mohd Rani ◽  
Zuraidah Abd Latif ◽  
Paveethra a/p Kani ◽  
Asmalita Syaiful ◽  
...  
Keyword(s):  
Observational Study ◽  
Adverse Drug Reactions ◽  
Prospective Observational Study ◽  
Drug Reactions ◽  
Paediatric Ward

scholarly journals Adverse drug reactions due to cancer chemotherapy in a tertiary care hospital in south Karnataka: a prospective observational study

2019 ◽  
Vol 8 (12) ◽  
pp. 2635
Author(s):  
Sowmya M. S. ◽  
Basavanna P. L. ◽  
L. Raghavendra Gupta
Keyword(s):  
Observational Study ◽  
Adverse Drug Reactions ◽  
Cancer Chemotherapy ◽  
Prospective Observational Study ◽  
Adverse Reactions ◽  
Tertiary Care ◽  
Care Hospital ◽  
Chemotherapeutic Drugs ◽  
Drug Reactions ◽  
Active Monitoring

Background: Cancer is a multi-cellular disease which can arise from any cell type and organs. Adverse drug reactions (ADR) are undesirable consequence of cancer chemotherapeutic drugs. A great importance has to be given for their assessment, detection, monitoring, reporting and preventing these ADR for the beneficial effects of the patients. So the present study was undertaken for the purpose of detecting and quantifying those adverse reactions which is of some importance in therapeutic setting.Methods: A prospective observational study conducted in chemotherapy ward, male and female patients of any age receiving cancer chemotherapy and presenting with ADR’s in duration of 3 months.Results: 160 patients were observed. Out of 160 patients 123 presented with ADR’s. Most common ADR’s were loss of appetite (67.6), diarrhea (61.8%), vomiting (21.5%), nausea (17.7%), anemia (24.7%). Cisplatin, paclitaxel, oxaliplatin, doxorubicin, gefitinib are common drugs causing ADR’s.Conclusions: Cancer chemotherapeutic drugs are associated with various adverse reactions. This study shows the importance of active monitoring of these reactions and measures to prevent their effects early in the treatment of cancer.

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