Transcutaneous oximetry and laser Doppler flowmetry values in patients with chronic skin ulcers treated with platelet rich plasma and stromal vascular fraction cells: a pilot study

2018 ◽  
Vol 41 (5) ◽  
pp. 577-582 ◽  
Author(s):  
Edoardo Raposio ◽  
Nicolò Bertozzi ◽  
Marco Trevisan ◽  
Michele Pio Grieco
Medicina ◽  
2021 ◽  
Vol 57 (10) ◽  
pp. 1081
Author(s):  
Martha Alicia Laredo-Naranjo ◽  
Nuria Patiño-Marín ◽  
Gabriel Alejandro Martínez-Castañón ◽  
Carlo Eduardo Medina-Solís ◽  
Carolina Velázquez-Hernández ◽  
...  

Background and Objectives: Orthodontic tooth movement is associated with inflammatory responses. The aim of this study was to identify gingival microcirculation using laser Doppler flowmetry in patients with orthodontic treatment. Materials and Methods: A longitudinal pilot study was performed. The participants were selected using a non-probability consecutive sampling. Of the twenty-five subjects, a total of six (four women and two men) complied with the criteria. Before and during the treatment, the oral hygiene index, gingival index, probing depth, level of epithelial attachment, and gingival microcirculation were evaluated with laser Doppler flowmetry (integrated parameters: 1. integrated primary basal flow (IPBF), 2. integrated total secondary real flow (ITSRF), and 3. difference between integration (DBI)) in all of the participants). Results: (a) An increase in gingival blood flow was identified at all time intervals with different arches during orthodontic treatment. (b) The IPBF and ITSRF (with treatment) identified after 20 min (treatment initial stage) were compared with the different time intervals, and we observed an increase in gingival perfusion at the 24th, 48th, and 72nd hours in some arches. (b) In the DBI, we found statistically significant differences (p < 0.005) in the Nitinol group of 0.016 inches among all the time intervals (24 h, 48 h, and 72 h) within the 30-day interval, observing a flow increase three times greater than the basal flow after 30 days. Conclusions: Healthcare professionals must identify the inflammatory processes in treatment to observe and discontinue use of harmful methods in clinical practice.


2001 ◽  
Vol 16 (3) ◽  
pp. 184-191 ◽  
Author(s):  
A. Sandner-Kiesling ◽  
G. Litscher ◽  
H. Voit-Augustin ◽  
R.L. James ◽  
G. Schwarz

2020 ◽  
Vol 9 (5) ◽  
pp. 392-399
Author(s):  
Emanoele Paixão da Silva Silva ◽  
◽  
Raquel D’Aquino Garcia Caminha ◽  
Marcelo Junior Zanda ◽  
Paulo Sérgio da Silva Santos ◽  
...  

Background: Oral mucositis (OM) is an inflammation of the oral mucosa due to cancer therapy that compromises the patient’s quality of life. Laser Doppler flowmetry (LDF) is a non-invasive method to monitor microvascular blood flow (BF) in real-time. Purpose: Develop a method to evaluate BF in the genian region cheek in patients undergoing chemotherapy by LDF and compare the degrees of OM and pain with evaluation of BF. Material and methods: Evaluation of OM was performed using the World Health Organization (WHO) and Oral Mucositis Assessment Scale (OMAS) scales and the visual analog scale for pain evaluation. For flowmetry analysis, a laser Doppler flowmeter (moorVMSTM™, 780 nm wavelength and VP3 probe), fixed by an acrylic resin support was used; VP3 probe was positioned on the genian region and the patient’s head was stabilized with a neck pillow for an accurate measurement. The Wilcoxon test was used to compare the flowmetry results at the studied times. The Pearson correlation coefficient was used to evaluate relationships between BF and the WHO, OMAS and visual analog scales. Results: Eleven patients of both sexes, aged between 30 and 78 years, with OM were included. An increase in cutaneous BF was observed at the initial times of OM, with progressive reduction during the chemotherapy cycle. There was a statistical difference (p<0.05) between time point T0 (first consultation) and time point T6 (last consultation). Conclusion: The method developed in this pilot study is effective, reliable, and reproducible, and allows the evaluation of BF dynamics in the genian region using LDF of patients undergoing chemotherapy at risk of developing OM.


2010 ◽  
Vol 79 (1) ◽  
pp. 29-33 ◽  
Author(s):  
J. Svalestad ◽  
S. Hellem ◽  
G. Vaagbø ◽  
Å. Irgens ◽  
E. Thorsen

1988 ◽  
Vol 3 (4) ◽  
pp. 247-250
Author(s):  
Michele Lucarotti ◽  
John Lancaster ◽  
Helen Hewitt ◽  
David Leaper

Transcutaneous oximetry (Tc Po2), laser Doppler flowmetry (LDV) and arterial Doppler index (DI) have been used to predict healing in 20 patients with chronic leg ulcers. This study showed that patients with improving or healed ulcers had significantly higher Tc Po2 levels adjacent to the ulcer ( P < 0.02) and lower LDV ( P < 0.05) and a tendency to higher DI than worsening or static ones.


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