Magnetic resonance imaging in the diagnosis and management of choroid plexus carcinoma in children

2001 ◽  
Vol 31 (9) ◽  
pp. 624-630 ◽  
Author(s):  
M. B. Taylor ◽  
Ralph W. Jackson ◽  
D. G. Hughes ◽  
Neville B. Wright
2021 ◽  
Vol 15 (1) ◽  
Author(s):  
In Young Jo ◽  
Seung-Gu Yeo ◽  
Hyuk-Jin Oh ◽  
Jae-Sang Oh

Abstract Background Choroid plexus carcinoma is an intraventricular neoplasm originating from the choroid plexus epithelium and is of rare occurrence in adults. However, owing to the low prevalence of choroid plexus carcinoma, there is very limited information about the disease entity and treatment. Here we report a rare case of choroid plexus carcinoma in an adult patient. Case presentation A 46-year-old South Korean (East Asian) male presented with low back pain, headache, and diplopia. Magnetic resonance imaging demonstrated enhancing mass lesion in the left trigone, cerebellar with leptomeningeal spread. Surgery was performed via left parietal craniotomy, and the lesion was histologically confirmed to be choroid plexus carcinoma. The patient received adjuvant craniospinal irradiation for remnant mass and leptomeningeal spread. Magnetic resonance imaging performed immediately after completion of the treatment revealed a partial decrease in the size of the tumor. However, the patient expired died as a result of acute respiratory distress syndrome before follow-up of long-term outcome. Conclusion Choroid plexus carcinoma with leptomeningeal spread in adults is very important for rapid diagnosis and treatment. In the case of the presence of leptomeningeal spread, craniospinal irradiation can be considered as a treatment method, but may have serious complications. Hence, the technique should be applied with care.


1993 ◽  
Vol 55 (5) ◽  
pp. 875-876 ◽  
Author(s):  
Fumihito OHASHI ◽  
Takao KOTANI ◽  
Takafumi ONISHI ◽  
Hiromu KATAMOTO ◽  
Erika NAKATA ◽  
...  

Neurosurgery ◽  
2009 ◽  
Vol 65 (4) ◽  
pp. E816-E817 ◽  
Author(s):  
Alan P. Lozier ◽  
Yamil M. Arbaje ◽  
Bernd W. Scheithauer

Abstract OBJECTIVE Choroid plexus carcinoma (CPCa) is an uncommon tumor rarely occurring in patients older than 2 years of age. The case reported herein represents the first documented example of a primary supratentorial, extraventricular CPCa in an adult. The scant literature regarding this topic is reviewed. CLINICAL PRESENTATION A 68-year-old woman presented with transient expressive aphasia. Magnetic resonance imaging demonstrated an avidly enhancing, left temporal, extra-axial mass with associated parenchymal cysts. INTERVENTION The tumor was gross-totally removed via a frontotemporal craniotomy. A diagnosis of CPCa was made on histological, immunohistochemical, and ultrastructural grounds. Postoperatively, the patient was treated by local radiotherapy and temozolomide. A magnetic resonance imaging scan 44 months after surgery showed no evidence of residual or recurrent tumor. CONCLUSION CPCa infrequently affects adults. Only rarely does it present as a supratentorial, extraventricular mass. Resection is the mainstay of therapy. Adjuvant radiation and chemotherapy are rational treatment options.


2017 ◽  
Vol 53 (5) ◽  
pp. 265-269 ◽  
Author(s):  
Carmen L. Yeamans ◽  
Rodrigo Gutierrez-Quintana ◽  
Allison Haley ◽  
Catherine G. Lamm

ABSTRACT A 5 yr old castrated male whippet presented with a unique presentation of ambulatory paraparesis and subsequent diagnosis of primary intracranial choroid plexus carcinoma, with metastases to the cervical, thoracic, lumbar, and sacral spinal cord segments. Magnetic resonance imaging was performed initially of the thoracolumbar vertebral column and was followed by MRI sequences of the brain for confirmation of the presence of a primary intracranial tumor. The dog was euthanized immediately following diagnostic imaging due to the severity of clinical signs and poor prognosis. Postmortem examination confirmed the presence of a primary choroid plexus carcinoma, with diffuse metastatic lesions to the spinal cord. To the authors’ knowledge, this is the first description of MRI findings of spinal cord metastasis of a choroid plexus carcinoma in a dog. Additionally, this case demonstrates primary clinical signs arising from metastatic lesions. This confirms the importance of extensive neuroimaging investigations when suspecting choroid plexus tumors and evaluating response to treatment regimens.


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