Inhibition of Vibrio biofilm formation by a marine actinomycete strain A66

2007 ◽  
Vol 76 (5) ◽  
pp. 1137-1144 ◽  
Author(s):  
JianLan You ◽  
XiaoLi Xue ◽  
LiXiang Cao ◽  
Xin Lu ◽  
Jian Wang ◽  
...  
Keyword(s):  
Biofilm Formation ◽  
Marine Actinomycete ◽  
Actinomycete Strain ◽  
Vibrio Biofilm

scholarly journals Antimicrobial Chlorinated 3-Phenylpropanoic Acid Derivatives from the Red Sea Marine Actinomycete Streptomyces coelicolor LY001

Marine Drugs ◽  
2020 ◽  
Vol 18 (9) ◽  
pp. 450 ◽  
Author(s):  
Lamiaa A. Shaala ◽  
Diaa T. A. Youssef ◽  
Torki A. Alzughaibi ◽  
Sameh S. Elhady
Keyword(s):  
Streptomyces Coelicolor ◽  
Acid Methyl Ester ◽  
Propanoic Acid ◽  
Ionization Mass ◽  
Acid Methyl ◽  
Marine Actinomycete ◽  
Actinomycete Strain ◽  
Derivatives Of ◽  
And Staphylococcus Aureus ◽  
Insight Into

The actinomycete strain Streptomyces coelicolor LY001 was purified from the sponge Callyspongia siphonella. Fractionation of the antimicrobial extract of the culture of the actinomycete afforded three new natural chlorinated derivatives of 3-phenylpropanoic acid, 3-(3,5-dichloro-4-hydroxyphenyl)propanoic acid (1), 3-(3,5-dichloro-4-hydroxyphenyl)propanoic acid methyl ester (2), and 3-(3-chloro-4-hydroxyphenyl)propanoic acid (3), together with 3-phenylpropanoic acid (4), E-cinnamic acid (5), and the diketopiperazine alkaloids cyclo(l-Phe-trans-4-OH-l-Pro) (6) and cyclo(l-Phe-cis-4-OH-d-Pro) (7) were isolated. Interpretation of nuclear magnetic resonance (NMR) and high-resolution electrospray ionization mass spectrometry (HRESIMS) data of 1–7 supported their assignments. Compounds 1–3 are first candidates of the natural chlorinated phenylpropanoic acid derivatives. The production of the chlorinated derivatives of 3-phenylpropionic acid (1–3) by S. coelicolor provides insight into the biosynthetic capabilities of the marine-derived actinomycetes. Compounds 1–3 demonstrated significant and selective activities towards Escherichia. coli and Staphylococcus aureus, while Candida albicans displayed more sensitivity towards compounds 6 and 7, suggesting a selectivity effect of these compounds against C. albicans.

Seawater requirement for the production of lipoxazolidinones by marine actinomycete strain NPS8920

2008 ◽  
Vol 35 (7) ◽  
pp. 761-765 ◽  
Author(s):  
Michelle J. Sunga ◽  
Sy Teisan ◽  
Ginger Tsueng ◽  
Venkat R. Macherla ◽  
Kin S. Lam
Keyword(s):  
Marine Actinomycete ◽  
Actinomycete Strain

Ginger and its component shogaol inhibit Vibrio biofilm formation in vitro and orally protect shrimp against acute hepatopancreatic necrosis disease (AHPND)

Aquaculture ◽  
2019 ◽  
Vol 504 ◽  
pp. 139-147 ◽  
Author(s):  
Chumporn Soowannayan ◽  
Sasithorn Boonmee ◽  
Sukanya Puckcharoen ◽  
Thitima Anatamsombat ◽  
Pattanan Yatip ◽  
...  
Keyword(s):  
Biofilm Formation ◽  
Acute Hepatopancreatic Necrosis Disease ◽  
Vibrio Biofilm

scholarly journals Abyssomicins—A 20-Year Retrospective View

Marine Drugs ◽  
2021 ◽  
Vol 19 (6) ◽  
pp. 299
Author(s):  
Hans-Peter Fiedler
Keyword(s):  
Selective Inhibition ◽  
The Sea Of Japan ◽  
Gram Positive Bacteria ◽  
New Family ◽  
Retrospective View ◽  
Marine Actinomycete ◽  
Actinomycete Strain ◽  
Resistant Strains ◽  
Vancomycin Resistant ◽  
Acid Pathway

Abyssomicins represent a new family of polycyclic macrolactones. The first described compounds of the abyssomicin family were abyssomicin B, C, atrop-C, and D, produced by the marine actinomycete strain Verrucosispora maris AB-18-032, which was isolated from a sediment collected in the Sea of Japan. Among the described abyssomicins, only abyssomicin C and atrop-abyssomicin C show a high antibiotic activity against Gram-positive bacteria, including multi-resistant and vancomycin-resistant strains. The inhibitory activity is caused by a selective inhibition of the enzyme 4-amino-4-deoxychorismate synthase, which catalyzes the transformation of chorismate to para-aminobenzoic acid, an intermediate in the folic acid pathway.

scholarly journals Isolation and characterisation of rifamycin W and phenylethylamides from a Fijian marine actinomycete Salinispora arenicola

2014 ◽  
Vol 32 (2) ◽  
pp. 43 ◽  
Author(s):  
Kavita Ragini ◽  
William Aalbersberg
Keyword(s):  
Antibacterial Activity ◽  
High Resolution ◽  
Fermentation Broth ◽  
Marine Actinomycete ◽  
Actinomycete Strain ◽  
Detailed Interpretation

An ansamycin, rifamycin W, and three phenylethylamides, N-(2'-phenylethyl)isobutyramide, 2-methyl-N-(2'-phenylethyl)butyramide, and N-(2'-phenylethyl)isovaleramide were isolated from the fermentation broth of amarine actinomycete strain identified as Salinispora arenicola. The structures of these compounds were confirmed by detailed interpretation of NMR spectroscopic and high resolution ESILC-MS data. Moderate antibacterial activity was observed for rifamycin W only.

scholarly journals Williamsia maris sp. nov., a novel actinomycete isolated from the Sea of Japan

2004 ◽  
Vol 54 (1) ◽  
pp. 191-194 ◽  
Author(s):  
James E. M. Stach ◽  
Luis A. Maldonado ◽  
Alan C. Ward ◽  
Alan T. Bull ◽  
Michael Goodfellow
Keyword(s):  
New Species ◽  
Type Strain ◽  
Gene Tree ◽  
The Sea Of Japan ◽  
Rrna Gene ◽  
Phenotypic Properties ◽  
Phenotypic Data ◽  
Marine Actinomycete ◽  
Actinomycete Strain ◽  
Taxonomic Approach

The taxonomic position of a marine actinomycete, strain SJS0289/JS1T, was determined using a polyphasic taxonomic approach. The organism, which had phenotypic properties consistent with its classification in the genus Williamsia, formed a distinct clade in the 16S rRNA gene tree together with the type strain of Williamsia muralis, but was readily distinguished from this species using DNA–DNA relatedness and phenotypic data. The genotypic and phenotypic data show that the organism merits recognition as a new species of Williamsia. The name proposed for the new species is Williamsia maris; the type strain is SJS0289/JS1T (=DSM 44693T=JCM 12070T=KCTC 9945T=NCIMB 13945T).

scholarly journals Maipomycin A, a Novel Natural Compound With Promising Anti-biofilm Activity Against Gram-Negative Pathogenic Bacteria

2021 ◽  
Vol 11 ◽  
Author(s):  
Junliang Zhang ◽  
Xiaoyan Liang ◽  
Shiling Zhang ◽  
Zhiman Song ◽  
Changyun Wang ◽  
...  
Keyword(s):  
Biofilm Formation ◽  
Pathogenic Bacteria ◽  
Complex Structure ◽  
Iron Chelator ◽  
Gram Negative Bacteria ◽  
Inhibition Activity ◽  
Biofilm Inhibition ◽  
Gram Negative ◽  
X Ray Crystallography ◽  
Actinomycete Strain

Pathogenic bacterial biofilms play an important role in recurrent nosocomial and medical device-related infections. Once occurred, the complex structure of the biofilm promotes the development of antibiotic resistance and becomes extremely difficult to eradicate. Here we describe a novel and effective anti-biofilm compound maipomycin A (MaiA), which was isolated from the metabolites of a rare actinomycete strain Kibdelosporangium phytohabitans XY-R10. Its structure was deduced from analyses of spectral data and confirmed by single-crystal X-ray crystallography. This natural product demonstrated a broad spectrum of anti-biofilm activities against Gram-negative bacteria. Interestingly, the addition of Fe(II) or Fe(III) ions could block the biofilm inhibition activity of MaiA because it is an iron chelator. However, not all iron chelators showed biofilm inhibition activity, suggesting that MaiA prevents biofilm formation through a specific yet currently undefined pathway. Furthermore, MaiA acts as a synergist to enhance colistin efficacy against Acinetobacter baumannii. Our results indicate that MaiA may potentially serve as an effective antibiofilm agent to prevent Gram-negative biofilm formation in future clinical applications.

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