Impact of rigid and nonrigid registration on the determination of 18F-FDG PET-based tumour volume and standardized uptake value in patients with lung cancer

2011 ◽  
Vol 38 (5) ◽  
pp. 856-864 ◽  
Author(s):  
Aleksandar Grgic ◽  
Elena Ballek ◽  
Jochen Fleckenstein ◽  
Norbert Moca ◽  
Stephanie Kremp ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Fdg Pet ◽  
Standardized Uptake Value ◽  
Tumour Volume ◽  
Nonrigid Registration ◽  
18F Fdg

Standardized uptake value differences between primary and metastatic lesions in 18F-FDG PET/CT of patients with lung cancer

2014 ◽  
Vol 56 (11) ◽  
pp. 1329-1335 ◽  
Author(s):  
Nobuyuki Kosaka ◽  
Tatsuro Tsuchida ◽  
Kazunobu Tsuji ◽  
Kazuhiro Shimizu ◽  
Hirohiko Kimura
Keyword(s):  
Lung Cancer ◽  
Fdg Pet ◽  
Standardized Uptake Value ◽  
Value Differences ◽  
Metastatic Lesions ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Role of 18F-PET-CT to predict pathological response after neoadjuvant treatment of rectal cancer

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Riccardo Caruso ◽  
Emilio Vicente ◽  
Yolanda Quijano ◽  
Hipolito Duran ◽  
Isabel Fabra ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Fdg Pet ◽  
Locally Advanced ◽  
Neoadjuvant Treatment ◽  
Standardized Uptake Value ◽  
Tumour Regression Grade ◽  
Pet Ct ◽  
Significant Difference ◽  
18F Fdg ◽  
Fdg Pet Ct

Abstract Objectives Neoadjuvant chemoradiation (nCRT) is universally considered to be a valid treatment to achieve downstaging, to improve local disease control and to obtain better resectability in locally advanced rectal cancer (LARC). The aim of this study is to correlate the change in the tumour 18F-FDG PET-CT standardized uptake value (SUV) before and after nCRT, in order to obtain an early prediction of the pathologic response (pR) achieved in patients with LARC. Data description We performed a retrospective analysis of patients with LARC diagnosis who underwent curative resection. All patients underwent a baseline 18F-FDG PET-CT scan within the week prior to the initiation of the treatment (PET-CT SUV1) and a second scan (PET-CT SUV2) within 6 weeks of the completion of nCRT. We evaluated the prognostic value of 18F-FDG PET-CT in terms of disease-free survival (DFS) and overall survival (OS) in patients with LARC.A total of 133 patients with LARC were included in the study. Patients were divided in two groups according to the TRG (tumour regression grade): 107 (80%) as the responders group (TRG0-TRG1) and 26 (25%) as the no-responders group (TRG2-TRG3). We obtained a significant difference in Δ%SUV between the two different groups; responders versus no-responders (p < 0.012). The results of this analysis show that 18F-FDG PET-CT may be an indicator to evaluate the pR to nCRT in patients with LARC. The decrease in 18F-FDG PET-CT uptake in the primary tumour may offer important information in order for an early identification of those patients more likely to obtain a pCR to nCRT and to predict those who are unlikely to significantly regress.

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