Induction of intratumoral tumor necrosis factor by a synthetic lipid A analog, ONO-4007, with less tolerance in repeated administration and its implication in potent antitumor effects with low toxicity

2002 ◽  
Vol 50 (12) ◽  
pp. 653-662 ◽  
Author(s):  
Motonobu Satoh, Kazusa Tsurumaki, Hideaki Ka
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Lipid A ◽  
Repeated Administration ◽  
Antitumor Effects ◽  
Low Toxicity ◽  
Necrosis Factor

Intratumoral Production of Tumor Necrosis Factor Augmented by Endogenous Interferons Results in Potent Antitumor Effects of DT-5461, a Synthetic Lipid A Analog

1995 ◽  
Vol 17 (2) ◽  
pp. 141-150 ◽  
Author(s):  
Eiji Kumazawa ◽  
Toshihiko Akimoto ◽  
Yasuo Kita ◽  
Takeshi Jimbo ◽  
Noriko Joto ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Lipid A ◽  
Antitumor Effects ◽  
Necrosis Factor

The Roles of Protein Phosphorylation/Dephosphorylation in Tumor Necrosis Factor Antitumor Effects

1996 ◽  
Vol 16 (12) ◽  
pp. 1021-1025 ◽  
Author(s):  
XIN-YUAN WANG ◽  
MICHAEL KAFKA ◽  
ALEXANDER DVILANSKY ◽  
ILANA NATHAN
Keyword(s):  
Tumor Necrosis Factor ◽  
Protein Phosphorylation ◽  
Tumor Necrosis ◽  
Antitumor Effects ◽  
Necrosis Factor

MONOPHOSPHORYL LIPID A PROTECTS AGAINST GRAM-POSITIVE SEPSIS AND TUMOR NECROSIS FACTOR

Shock ◽  
1994 ◽  
Vol 2 (4) ◽  
pp. 271-274 ◽  
Author(s):  
Mark E. Astiz ◽  
Angel Galera ◽  
Dhanonjoy C. Saha ◽  
Charles Carpati ◽  
Eric C. Rackow
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Lipid A ◽  
Gram Positive ◽  
Monophosphoryl Lipid A ◽  
Monophosphoryl Lipid ◽  
Necrosis Factor
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