Use of the Liver Tissue Oxygenation Index as a Noninvasive Parameter of Intestinal Ischemia in Rabbits

Study objectivesNear-infrared spectroscopy is a modality that can monitor tissue oxygenation index (TOI) and has potential to evaluate return of spontaneous circulation (ROSC) during cardiopulmonary resuscitation (CPR). This study’s objectives were to evaluate whether TOI could be associated with ROSC and used to help guide the decision to either terminate CPR or proceed to extracorporeal CPR (ECPR).MethodsIn this observational study, we assessed the patients with out-of-hospital cardiac arrest with non-traumatic cause receiving CPR on arrival at our ED between 2013 and 2016. TOI monitoring was discontinued either on CPR termination after ROSC was reached or on patient death. Patients were classified into two groups: ROSC and non-ROSC group.ResultsOut of 141 patients, 24 were excluded and the remaining 117 were classified as follows: ROSC group (n=44) and non-ROSC group (n=73). ROSC group was significantly younger and more likely to have their event witnessed and bystander CPR. ROSC group showed a higher initial TOI than non-ROSC group (60.5%±17.0% vs 37.9%±13.7%: p<0.01). Area under the curve analysis was more accurate with the initial TOI than without it for predicting ROSC (0.88, 95% CI 0.82 to 0.95 vs 0.79, 95% CI 0.70 to 0.87: p<0.01). TOI cut-off value ≥59% appeared to favour survival to hospital discharge whereas TOI ≤24% was associated with non-ROSC.ConclusionsThis study demonstrated an association between higher initial TOI and ROSC. Initial TOI could increase the accuracy of ROSC prognosis and may be a clinical factor in the decision to terminate CPR and select patients who are to proceed to ECPR.

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Wearing of Cloth or Disposable Surgical Face Masks has no Effect on Vigorous Exercise Performance in Healthy Individuals

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17218110 ◽

2020 ◽

Vol 17 (21) ◽

pp. 8110

Author(s):

Keely Shaw ◽

Scotty Butcher ◽

Jongbum Ko ◽

Gordon A. Zello ◽

Philip D. Chilibeck

Keyword(s):

Oxygen Saturation ◽

Exercise Performance ◽

Tissue Oxygenation ◽

Arterial Oxygen Saturation ◽

Oxygenation Index ◽

Arterial Oxygen ◽

Time To Exhaustion ◽

Vigorous Exercise ◽

Exercise Tests ◽

Tissue Oxygenation Index

Wearing face masks is recommended for the prevention of contracting or exposing others to cardiorespiratory infections, such as COVID-19. Controversy exists on whether wearing face masks during vigorous exercise affects performance. We used a randomized, counterbalanced cross-over design to evaluate the effects of wearing a surgical mask, a cloth mask, or no mask in 14 participants (7 men and 7 women; 28.2 ± 8.7 y) during a cycle ergometry test to exhaustion. Arterial oxygen saturation (pulse oximetry) and tissue oxygenation index (indicator of hemoglobin saturation/desaturation) at vastus lateralis (near-infrared spectroscopy) were assessed throughout the exercise tests. Wearing face masks had no effect on performance (time to exhaustion (mean ± SD): no mask 622 ± 141 s, surgical mask 657 ± 158 s, cloth mask 637 ± 153 s (p = 0.20); peak power: no mask 234 ± 56 W, surgical mask 241 ± 57 W, cloth mask 241 ± 51 W (p = 0.49)). When expressed relative to peak exercise performance, no differences were evident between wearing or not wearing a mask for arterial oxygen saturation, tissue oxygenation index, rating of perceived exertion, or heart rate at any time during the exercise tests. Wearing a face mask during vigorous exercise had no discernable detrimental effect on blood or muscle oxygenation, and exercise performance in young, healthy participants (ClinicalTrials.gov, NCT04557605).

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Use of Tissue Oxygenation Index and Fractional Tissue Oxygen Extraction as Non-Invasive Parameters for Cerebral Oxygenation

Neonatology ◽

10.1159/000101063 ◽

2007 ◽

Vol 92 (2) ◽

pp. 120-126 ◽

Cited By ~ 129

Author(s):

Gunnar Naulaers ◽

Bart Meyns ◽

Marc Miserez ◽

Veerle Leunens ◽

Sabine Van Huffel ◽

...

Keyword(s):

Tissue Oxygenation ◽

Cerebral Oxygenation ◽

Oxygenation Index ◽

Oxygen Extraction ◽

Tissue Oxygen ◽

Non Invasive ◽

Tissue Oxygenation Index

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Cerebral tissue oxygenation index and superior vena cava blood flow in the very low birth weight infant

Acta Paediatrica ◽

10.1111/j.1651-2227.2008.01006.x ◽

2009 ◽

Vol 98 (1) ◽

pp. 43-46 ◽

Cited By ~ 36

Author(s):

M Moran ◽

J Miletin ◽

K Pichova ◽

EM Dempsey

Keyword(s):

Blood Flow ◽

Tissue Oxygenation ◽

Very Low Birth Weight ◽

Superior Vena ◽

Vena Cava ◽

Oxygenation Index ◽

Cerebral Tissue ◽

Low Birth Weight Infant ◽

Tissue Oxygenation Index ◽

Cerebral Tissue Oxygenation

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Non-invasive assessment of tissue oxygenation parameters in diabetic patients foot sole using near infrared spectroscopy

Biomedical Spectroscopy and Imaging ◽

10.3233/bsi-210211 ◽

2021 ◽

pp. 1-10

Author(s):

M. Brindha ◽

N.P. Guhan Seshadri ◽

R. Periyasamy

Keyword(s):

Infrared Spectroscopy ◽

Near Infrared Spectroscopy ◽

Near Infrared ◽

Tissue Oxygenation ◽

Oxygenation Index ◽

Diabetic Group ◽

Diabetic Patients ◽

Significant Difference ◽

Tissue Hardness ◽

Tissue Oxygenation Index

Background and Objective: Diabetic problems are more common in the lower extremity and linked with high mortality rate which affects public health system. The present study focused on monitoring the changes in tissue oxygenation concentrations using Near infrared spectroscopy system along with temperature and hardness of the foot tissues. Methods: Control subjects (without diabetes) and diabetic patients without neuropathy were selected for this study and three standard foot risk areas were considered. Standard induced ischemic stimulus was given to assess the response of the designed system and to analyze the changes in oxyhemoglobin and deoxyhemoglobin levels during venous occlusion. Results: Results showed significant differences in the tissue oxygenation index value in all three standard areas where oxygenation value at the foot areas were significantly low ( p < 0.05) in diabetic group as compared to control group. Also, significant difference were found in tissue hardness value when comparing between groups, where the diabetic group had significantly high ( p < 0.05) tissue hardness at area 5 and area 8 as compared to control groups. Conclusion: Therefore, the present study concludes that high tissue hardness had significant effect on tissue oxygenation index that affects vascular circulation and this condition could be assessable using NIRS technique in order to find risky areas at the foot sole.

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