Upregulation of TRIB2 by Wnt/β-catenin activation in BRAFV600E papillary thyroid carcinoma cells confers resistance to BRAF inhibitor vemurafenib

2021 ◽  
Author(s):  
Nianxue Wang ◽  
Jing Wen ◽  
Wei Ren ◽  
Yuting Wu ◽  
Chaonan Deng
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Braf Inhibitor ◽  
Carcinoma Cells ◽  
Papillary Thyroid

scholarly journals MicroRNA‐524‐5p suppresses the progression of papillary thyroid carcinoma cells via targeting on FOXE1 and ITGA3 in cell autophagy and cycling pathways

2019 ◽  
Vol 234 (10) ◽  
pp. 18382-18391 ◽  
Author(s):  
Hui Liu ◽  
Xi Chen ◽  
Ting Lin ◽  
Xingsheng Chen ◽  
Jiqi Yan ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Carcinoma Cells ◽  
Papillary Thyroid

TBX3 promotes proliferation of papillary thyroid carcinoma cells through facilitating PRC2-mediated p57KIP2 repression

Oncogene ◽  
2018 ◽  
Vol 37 (21) ◽  
pp. 2773-2792 ◽  
Author(s):  
Xiaomeng Li ◽  
Xianhui Ruan ◽  
Peitao Zhang ◽  
Yang Yu ◽  
Ming Gao ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Carcinoma Cells ◽  
Papillary Thyroid

scholarly journals Prognosis of Patients with Papillary Thyroid Carcinoma Located in One Lobe Showing Lateral Node Metastasis in the Contralateral but Not Ipsilateral Compartment

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Yasuhiro Ito ◽  
Takuya Higashiyama ◽  
Yuuki Takamura ◽  
Kaoru Kobayashi ◽  
Akihiro Miya ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Lateral Compartment ◽  
Carcinoma Cells ◽  
Papillary Thyroid ◽  
Lateral Node ◽  
Node Metastasis ◽  
Central Node ◽  
Central Node Metastasis ◽  
Central Node Dissection

Papillary thyroid carcinoma (PTC) frequently metastasizes to the lymph node in lateral compartment, which can often be detected on preoperative ultrasonography (N1b). However, PTC located in one lobe showing contralateral but not ipsilateral N1b is not common. We analyzed the clinicopathological features and prognosis of 13 patients with PTC limited in one lobe showing contralateral but not ipsilateral N1b. Sizes of the primary lesions ranged from 0.8 cm to 3.0 cm and only 2 tumors showed extrathyroid extension. Metastatic lateral node measured from 0.6 to 3.1 cm. Ten patients showed pathological central node metastasis and 5 had minute PTC lesions in the contralateral lobe. However, 3 patients did not show either of these. None of the patients have developed carcinoma recurrence or died of carcinoma to date. Taken together, PTC located in one lobe with contralateral but not ipsilateral N1b is rare and generally shows an indolent behavior. Although most patients had central node metastasis and/or minute PTC lesions in the contralateral lobe, it is also possible for carcinoma cells to metastasize directly from primary lesions to the contralateral lateral node. Total thyroidectomy with central node dissection and therapeutic MND of the contralateral compartment may be an acceptable surgical design and bilateral MND might not be mandatory.

Abstract 520: Inhibition of uPAR and uPA reduces invasion and degradative potential in papillary thyroid carcinoma cells

2010 ◽  
Author(s):  
Theodore S. Nowicki ◽  
Nicolas T. Kummer ◽  
Codrin Iacob ◽  
Nina Suslina ◽  
Augustine Moscatello ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Carcinoma Cells ◽  
Papillary Thyroid
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